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CANT1 (calcium activated nucleotidase 1)

Identity

Alias (NCBI)DBQD
DBQD1
EDM7
SCAN-1
SCAN1
SHAPY
HGNC (Hugo) CANT1
HGNC Alias symbSHAPY
SCAN-1
HGNC Alias nameSoluble Ca-Activated Nucleotidase, isozyme 1
 apyrase 1 homolog (C. lectularius)
LocusID (NCBI) 124583
Atlas_Id 52312
Location 17q25.3  [Link to chromosome band 17q25]
Location_base_pair Starts at 78991716 and ends at 79009764 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CANT1 (17q25.3) / CANT1 (17q25.3)CANT1 (17q25.3) / ETV1 (7p21.2)CANT1 (17q25.3) / ETV4 (17q21.31)
CANT1 (17q25.3) / FBXL20 (17q12)CANT1 (17q25.3) / PPP3CA (4q24)CANT1 (17q25.3) / PSMD3 (17q21.1)
ETV4 (17q21.31) / CANT1 (17q25.3)HNRNPA2B1 (7p15.2) / CANT1 (17q25.3)CANT1 17q25.3 / ETV4 17q21.31
CANT1 17q25.3 / FBXL20 17q12CANT1 17q25.3 / PPP3CA 4q24CANT1 17q25.3 / PSMD3 17q21.1
HNRNPA2B1 7p15.2 / CANT1 17q25.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)CANT1   19721
Cards
Entrez_Gene (NCBI)CANT1    calcium activated nucleotidase 1
AliasesDBQD; DBQD1; EDM7; SCAN-1; 
SCAN1; SHAPY
GeneCards (Weizmann)CANT1
Ensembl hg19 (Hinxton)ENSG00000171302 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171302 [Gene_View]  ENSG00000171302 [Sequence]  chr17:78991716-79009764 [Contig_View]  CANT1 [Vega]
ICGC DataPortalENSG00000171302
TCGA cBioPortalCANT1
AceView (NCBI)CANT1
Genatlas (Paris)CANT1
SOURCE (Princeton)CANT1
Genetics Home Reference (NIH)CANT1
Genomic and cartography
GoldenPath hg38 (UCSC)CANT1  -     chr17:78991716-79009764 -  17q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CANT1  -     17q25.3   [Description]    (hg19-Feb_2009)
GoldenPathCANT1 - 17q25.3 [CytoView hg19]  CANT1 - 17q25.3 [CytoView hg38]
ImmunoBaseENSG00000171302
Genome Data Viewer NCBICANT1 [Mapview hg19]  
OMIM251450   613165   617719   
Gene and transcription
Genbank (Entrez)AB097006 AB097033 AF328554 AJ312208 AK026161
RefSeq transcript (Entrez)NM_001159772 NM_001159773 NM_138793
Consensus coding sequences : CCDS (NCBI)CANT1
Gene ExpressionCANT1 [ NCBI-GEO ]   CANT1 [ EBI - ARRAY_EXPRESS ]   CANT1 [ SEEK ]   CANT1 [ MEM ]
Gene Expression Viewer (FireBrowse)CANT1 [ Firebrowse - Broad ]
GenevisibleExpression of CANT1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)124583
GTEX Portal (Tissue expression)CANT1
Human Protein AtlasENSG00000171302-CANT1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WVQ1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WVQ1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WVQ1
PhosPhoSitePlusQ8WVQ1
Domains : Interpro (EBI)Apyrase    Apyrase_sf   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)CANT1
PDB (RSDB)1S18    1S1D    2H2N    2H2U   
PDB Europe1S18    1S1D    2H2N    2H2U   
PDB (PDBSum)1S18    1S1D    2H2N    2H2U   
PDB (IMB)1S18    1S1D    2H2N    2H2U   
Structural Biology KnowledgeBase1S18    1S1D    2H2N    2H2U   
SCOP (Structural Classification of Proteins)1S18    1S1D    2H2N    2H2U   
CATH (Classification of proteins structures)1S18    1S1D    2H2N    2H2U   
SuperfamilyQ8WVQ1
AlphaFold pdb e-kbQ8WVQ1   
Human Protein Atlas [tissue]ENSG00000171302-CANT1 [tissue]
HPRD13003
Protein Interaction databases
DIP (DOE-UCLA)Q8WVQ1
IntAct (EBI)Q8WVQ1
BioGRIDCANT1
STRING (EMBL)CANT1
ZODIACCANT1
Ontologies - Pathways
QuickGOQ8WVQ1
Ontology : AmiGOguanosine-diphosphatase activity  guanosine-diphosphatase activity  calcium ion binding  protein binding  extracellular region  endoplasmic reticulum membrane  Golgi apparatus  plasma membrane  membrane  integral component of membrane  proteoglycan biosynthetic process  proteoglycan biosynthetic process  Golgi cisterna membrane  specific granule lumen  protein homodimerization activity  positive regulation of I-kappaB kinase/NF-kappaB signaling  adenosine-diphosphatase activity  neutrophil degranulation  uridine-diphosphatase activity  extracellular exosome  tertiary granule lumen  ficolin-1-rich granule lumen  
Ontology : EGO-EBIguanosine-diphosphatase activity  guanosine-diphosphatase activity  calcium ion binding  protein binding  extracellular region  endoplasmic reticulum membrane  Golgi apparatus  plasma membrane  membrane  integral component of membrane  proteoglycan biosynthetic process  proteoglycan biosynthetic process  Golgi cisterna membrane  specific granule lumen  protein homodimerization activity  positive regulation of I-kappaB kinase/NF-kappaB signaling  adenosine-diphosphatase activity  neutrophil degranulation  uridine-diphosphatase activity  extracellular exosome  tertiary granule lumen  ficolin-1-rich granule lumen  
Pathways : KEGGPurine metabolism    Pyrimidine metabolism   
NDEx NetworkCANT1
Atlas of Cancer Signalling NetworkCANT1
Wikipedia pathwaysCANT1
Orthology - Evolution
OrthoDB124583
GeneTree (enSembl)ENSG00000171302
Phylogenetic Trees/Animal Genes : TreeFamCANT1
Homologs : HomoloGeneCANT1
Homology/Alignments : Family Browser (UCSC)CANT1
Gene fusions - Rearrangements
Fusion : MitelmanCANT1/ETV4 [17q25.3/17q21.31]  
Fusion : MitelmanCANT1/FBXL20 [17q25.3/17q12]  
Fusion : MitelmanCANT1/PPP3CA [17q25.3/4q24]  
Fusion : MitelmanCANT1/PSMD3 [17q25.3/17q21.1]  
Fusion : MitelmanHNRNPA2B1/CANT1 [7p15.2/17q25.3]  
Fusion : QuiverCANT1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCANT1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CANT1
dbVarCANT1
ClinVarCANT1
MonarchCANT1
1000_GenomesCANT1 
Exome Variant ServerCANT1
GNOMAD BrowserENSG00000171302
Varsome BrowserCANT1
ACMGCANT1 variants
VarityQ8WVQ1
Genomic Variants (DGV)CANT1 [DGVbeta]
DECIPHERCANT1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCANT1 
Mutations
ICGC Data PortalCANT1 
TCGA Data PortalCANT1 
Broad Tumor PortalCANT1
OASIS PortalCANT1 [ Somatic mutations - Copy number]
Cancer Gene: CensusCANT1 
Somatic Mutations in Cancer : COSMICCANT1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCANT1
Mutations and Diseases : HGMDCANT1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaCANT1
DgiDB (Drug Gene Interaction Database)CANT1
DoCM (Curated mutations)CANT1
CIViC (Clinical Interpretations of Variants in Cancer)CANT1
Cancer3DCANT1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM251450    613165    617719   
Orphanet1631   
DisGeNETCANT1
MedgenCANT1
Genetic Testing Registry CANT1
NextProtQ8WVQ1 [Medical]
GENETestsCANT1
Target ValidationCANT1
Huge Navigator CANT1 [HugePedia]
ClinGenCANT1
Clinical trials, drugs, therapy
MyCancerGenomeCANT1
Protein Interactions : CTDCANT1
Pharm GKB GenePA134984439
PharosQ8WVQ1
Clinical trialCANT1
Miscellaneous
canSAR (ICR)CANT1
HarmonizomeCANT1
DataMed IndexCANT1
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCANT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:02:10 CEST 2021

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