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CAPN14 (calpain 14)

Identity

Other alias-
HGNC (Hugo) CAPN14
LocusID (NCBI) 440854
Atlas_Id 61408
Location 2p23.1  [Link to chromosome band 2p23]
Location_base_pair Starts at 31173056 and ends at 31217545 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CAPN14 (2p23.1) / HERC3 (4q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CAPN14   16664
Cards
Entrez_Gene (NCBI)CAPN14  440854  calpain 14
Aliases
GeneCards (Weizmann)CAPN14
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr2:31173056-31217545 [Contig_View]  CAPN14 [Vega]
TCGA cBioPortalCAPN14
AceView (NCBI)CAPN14
Genatlas (Paris)CAPN14
WikiGenes440854
SOURCE (Princeton)CAPN14
Genetics Home Reference (NIH)CAPN14
Genomic and cartography
GoldenPath hg38 (UCSC)CAPN14  -     chr2:31173056-31217545 -  2p23.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CAPN14  -     2p23.1   [Description]    (hg19-Feb_2009)
EnsemblCAPN14 - 2p23.1 [CytoView hg19]  CAPN14 - 2p23.1 [CytoView hg38]
Mapping of homologs : NCBICAPN14 [Mapview hg19]  CAPN14 [Mapview hg38]
OMIM610229   
Gene and transcription
Genbank (Entrez)AA743820 AK092257 AK296910 BX091474 DC347418
RefSeq transcript (Entrez)NM_001145122 NM_001321270
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CAPN14
Cluster EST : UnigeneHs.468059 [ NCBI ]
CGAP (NCI)Hs.468059
Gene ExpressionCAPN14 [ NCBI-GEO ]   CAPN14 [ EBI - ARRAY_EXPRESS ]   CAPN14 [ SEEK ]   CAPN14 [ MEM ]
Gene Expression Viewer (FireBrowse)CAPN14 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)440854
GTEX Portal (Tissue expression)CAPN14
Protein : pattern, domain, 3D structure
UniProt/SwissProtA8MX76   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA8MX76  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA8MX76
Splice isoforms : SwissVarA8MX76
Catalytic activity : Enzyme3.4.22.- [ Enzyme-Expasy ]   3.4.22.-3.4.22.- [ IntEnz-EBI ]   3.4.22.- [ BRENDA ]   3.4.22.- [ KEGG ]   
PhosPhoSitePlusA8MX76
Domaine pattern : Prosite (Expaxy)CALPAIN_CAT (PS50203)    EF_HAND_1 (PS00018)    EF_HAND_2 (PS50222)    THIOL_PROTEASE_CYS (PS00139)   
Domains : Interpro (EBI)C2_III    Calpain_cysteine_protease    Calpain_domain_III    Calpain_III    EF-hand-dom_pair    EF_Hand_1_Ca_BS    EF_hand_dom    Pept_cys_AS    Peptidase_C2_calpain_cat   
Domain families : Pfam (Sanger)Calpain_III (PF01067)    Peptidase_C2 (PF00648)   
Domain families : Pfam (NCBI)pfam01067    pfam00648   
Domain families : Smart (EMBL)calpain_III (SM00720)  CysPc (SM00230)  
Conserved Domain (NCBI)CAPN14
DMDM Disease mutations440854
Blocks (Seattle)CAPN14
SuperfamilyA8MX76
Peptide AtlasA8MX76
IPIIPI00455530   IPI00895873   
Protein Interaction databases
DIP (DOE-UCLA)A8MX76
IntAct (EBI)A8MX76
BioGRIDCAPN14
STRING (EMBL)CAPN14
ZODIACCAPN14
Ontologies - Pathways
QuickGOA8MX76
Ontology : AmiGOcalcium-dependent cysteine-type endopeptidase activity  calcium ion binding  cytoplasm  proteolysis  
Ontology : EGO-EBIcalcium-dependent cysteine-type endopeptidase activity  calcium ion binding  cytoplasm  proteolysis  
NDEx NetworkCAPN14
Atlas of Cancer Signalling NetworkCAPN14
Wikipedia pathwaysCAPN14
Orthology - Evolution
OrthoDB440854
Phylogenetic Trees/Animal Genes : TreeFamCAPN14
HOVERGENA8MX76
HOGENOMA8MX76
Homologs : HomoloGeneCAPN14
Homology/Alignments : Family Browser (UCSC)CAPN14
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCAPN14 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CAPN14
dbVarCAPN14
ClinVarCAPN14
1000_GenomesCAPN14 
Exome Variant ServerCAPN14
ExAC (Exome Aggregation Consortium)CAPN14 (select the gene name)
Genetic variants : HAPMAP440854
Genomic Variants (DGV)CAPN14 [DGVbeta]
DECIPHERCAPN14 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCAPN14 
Mutations
ICGC Data PortalCAPN14 
TCGA Data PortalCAPN14 
Broad Tumor PortalCAPN14
OASIS PortalCAPN14 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCAPN14  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCAPN14
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CAPN14
DgiDB (Drug Gene Interaction Database)CAPN14
DoCM (Curated mutations)CAPN14 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CAPN14 (select a term)
intoGenCAPN14
Cancer3DCAPN14(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610229   
Orphanet
MedgenCAPN14
Genetic Testing Registry CAPN14
NextProtA8MX76 [Medical]
TSGene440854
GENETestsCAPN14
Target ValidationCAPN14
Huge Navigator CAPN14 [HugePedia]
snp3D : Map Gene to Disease440854
BioCentury BCIQCAPN14
ClinGenCAPN14
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD440854
Chemical/Pharm GKB GenePA134888839
Clinical trialCAPN14
Miscellaneous
canSAR (ICR)CAPN14 (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCAPN14
EVEXCAPN14
GoPubMedCAPN14
iHOPCAPN14
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:42:03 CEST 2017

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