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CAPN7 (calpain 7)

Identity

Alias_symbol (synonym)PalBH
Other aliasCALPAIN7
PALBH
HGNC (Hugo) CAPN7
LocusID (NCBI) 23473
Atlas_Id 61410
Location 3p25.1  [Link to chromosome band 3p25]
Location_base_pair Starts at 15206226 and ends at 15252916 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CAPN7 (3p25.1) / ACTR2 (2p14)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CAPN7   1484
Cards
Entrez_Gene (NCBI)CAPN7  23473  calpain 7
AliasesCALPAIN7; PALBH
GeneCards (Weizmann)CAPN7
Ensembl hg19 (Hinxton)ENSG00000131375 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000131375 [Gene_View]  chr3:15206226-15252916 [Contig_View]  CAPN7 [Vega]
ICGC DataPortalENSG00000131375
TCGA cBioPortalCAPN7
AceView (NCBI)CAPN7
Genatlas (Paris)CAPN7
WikiGenes23473
SOURCE (Princeton)CAPN7
Genetics Home Reference (NIH)CAPN7
Genomic and cartography
GoldenPath hg38 (UCSC)CAPN7  -     chr3:15206226-15252916 +  3p25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CAPN7  -     3p25.1   [Description]    (hg19-Feb_2009)
EnsemblCAPN7 - 3p25.1 [CytoView hg19]  CAPN7 - 3p25.1 [CytoView hg38]
Mapping of homologs : NCBICAPN7 [Mapview hg19]  CAPN7 [Mapview hg38]
OMIM606400   
Gene and transcription
Genbank (Entrez)AB028639 AK093742 AK314253 BC056202 BI464220
RefSeq transcript (Entrez)NM_014296
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CAPN7
Cluster EST : UnigeneHs.595234 [ NCBI ]
CGAP (NCI)Hs.595234
Alternative Splicing GalleryENSG00000131375
Gene ExpressionCAPN7 [ NCBI-GEO ]   CAPN7 [ EBI - ARRAY_EXPRESS ]   CAPN7 [ SEEK ]   CAPN7 [ MEM ]
Gene Expression Viewer (FireBrowse)CAPN7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23473
GTEX Portal (Tissue expression)CAPN7
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y6W3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y6W3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y6W3
Splice isoforms : SwissVarQ9Y6W3
Catalytic activity : Enzyme3.4.22.- [ Enzyme-Expasy ]   3.4.22.-3.4.22.- [ IntEnz-EBI ]   3.4.22.- [ BRENDA ]   3.4.22.- [ KEGG ]   
PhosPhoSitePlusQ9Y6W3
Domaine pattern : Prosite (Expaxy)CALPAIN_CAT (PS50203)   
Domains : Interpro (EBI)C2_III    Calpain_cysteine_protease    Calpain_domain_III    Calpain_III    MIT    Peptidase_C2_calpain_cat   
Domain families : Pfam (Sanger)Calpain_III (PF01067)    MIT (PF04212)    Peptidase_C2 (PF00648)   
Domain families : Pfam (NCBI)pfam01067    pfam04212    pfam00648   
Domain families : Smart (EMBL)calpain_III (SM00720)  CysPc (SM00230)  MIT (SM00745)  
Conserved Domain (NCBI)CAPN7
DMDM Disease mutations23473
Blocks (Seattle)CAPN7
PDB (SRS)2QFE   
PDB (PDBSum)2QFE   
PDB (IMB)2QFE   
PDB (RSDB)2QFE   
Structural Biology KnowledgeBase2QFE   
SCOP (Structural Classification of Proteins)2QFE   
CATH (Classification of proteins structures)2QFE   
SuperfamilyQ9Y6W3
Human Protein AtlasENSG00000131375
Peptide AtlasQ9Y6W3
HPRD05908
IPIIPI00003765   IPI00927915   IPI00925105   IPI00927473   IPI00926320   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y6W3
IntAct (EBI)Q9Y6W3
FunCoupENSG00000131375
BioGRIDCAPN7
STRING (EMBL)CAPN7
ZODIACCAPN7
Ontologies - Pathways
QuickGOQ9Y6W3
Ontology : AmiGOendopeptidase activity  calcium-dependent cysteine-type endopeptidase activity  protein binding  nucleoplasm  cytoplasm  cytosol  positive regulation of epithelial cell migration  nuclear body  extracellular exosome  MIT domain binding  self proteolysis  
Ontology : EGO-EBIendopeptidase activity  calcium-dependent cysteine-type endopeptidase activity  protein binding  nucleoplasm  cytoplasm  cytosol  positive regulation of epithelial cell migration  nuclear body  extracellular exosome  MIT domain binding  self proteolysis  
NDEx NetworkCAPN7
Atlas of Cancer Signalling NetworkCAPN7
Wikipedia pathwaysCAPN7
Orthology - Evolution
OrthoDB23473
GeneTree (enSembl)ENSG00000131375
Phylogenetic Trees/Animal Genes : TreeFamCAPN7
HOVERGENQ9Y6W3
HOGENOMQ9Y6W3
Homologs : HomoloGeneCAPN7
Homology/Alignments : Family Browser (UCSC)CAPN7
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCAPN7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CAPN7
dbVarCAPN7
ClinVarCAPN7
1000_GenomesCAPN7 
Exome Variant ServerCAPN7
ExAC (Exome Aggregation Consortium)CAPN7 (select the gene name)
Genetic variants : HAPMAP23473
Genomic Variants (DGV)CAPN7 [DGVbeta]
DECIPHERCAPN7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCAPN7 
Mutations
ICGC Data PortalCAPN7 
TCGA Data PortalCAPN7 
Broad Tumor PortalCAPN7
OASIS PortalCAPN7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCAPN7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCAPN7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CAPN7
DgiDB (Drug Gene Interaction Database)CAPN7
DoCM (Curated mutations)CAPN7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CAPN7 (select a term)
intoGenCAPN7
Cancer3DCAPN7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606400   
Orphanet
MedgenCAPN7
Genetic Testing Registry CAPN7
NextProtQ9Y6W3 [Medical]
TSGene23473
GENETestsCAPN7
Target ValidationCAPN7
Huge Navigator CAPN7 [HugePedia]
snp3D : Map Gene to Disease23473
BioCentury BCIQCAPN7
ClinGenCAPN7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23473
Chemical/Pharm GKB GenePA26064
Clinical trialCAPN7
Miscellaneous
canSAR (ICR)CAPN7 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCAPN7
EVEXCAPN7
GoPubMedCAPN7
iHOPCAPN7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:03:51 CEST 2017

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