Atlas of Genetics and Cytogenetics in Oncology and Haematology

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CARD18 (caspase recruitment domain family member 18)

Identity

Alias (NCBI)ICEBERG
UNQ5804
pseudo-ICE
HGNC (Hugo) CARD18
HGNC Alias symbUNQ5804
ICEBERG
pseudo-ICE
HGNC Previous namecaspase recruitment domain family, member 18
LocusID (NCBI) 59082
Atlas_Id 43312
Location 11q22.3  [Link to chromosome band 11q22]
Location_base_pair Starts at 105137715 and ends at 105139769 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CARD18   28861
Cards
Entrez_Gene (NCBI)CARD18  59082  caspase recruitment domain family member 18
AliasesICEBERG; UNQ5804; pseudo-ICE
GeneCards (Weizmann)CARD18
Ensembl hg19 (Hinxton)ENSG00000255501 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000255501 [Gene_View]  ENSG00000255501 [Sequence]  chr11:105137715-105139769 [Contig_View]  CARD18 [Vega]
ICGC DataPortalENSG00000255501
TCGA cBioPortalCARD18
AceView (NCBI)CARD18
Genatlas (Paris)CARD18
WikiGenes59082
SOURCE (Princeton)CARD18
Genetics Home Reference (NIH)CARD18
Genomic and cartography
GoldenPath hg38 (UCSC)CARD18  -     chr11:105137715-105139769 -  11q22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CARD18  -     11q22.3   [Description]    (hg19-Feb_2009)
GoldenPathCARD18 - 11q22.3 [CytoView hg19]  CARD18 - 11q22.3 [CytoView hg38]
ImmunoBaseENSG00000255501
genome Data Viewer NCBICARD18 [Mapview hg19]  
OMIM605354   
Gene and transcription
Genbank (Entrez)AF208005 AI189838 AW295205 AY358231 BC131610
RefSeq transcript (Entrez)NM_021571
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CARD18
Alternative Splicing GalleryENSG00000255501
Gene ExpressionCARD18 [ NCBI-GEO ]   CARD18 [ EBI - ARRAY_EXPRESS ]   CARD18 [ SEEK ]   CARD18 [ MEM ]
Gene Expression Viewer (FireBrowse)CARD18 [ Firebrowse - Broad ]
GenevisibleExpression of CARD18 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)59082
GTEX Portal (Tissue expression)CARD18
Human Protein AtlasENSG00000255501-CARD18 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP57730   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP57730  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP57730
Splice isoforms : SwissVarP57730
PhosPhoSitePlusP57730
Domaine pattern : Prosite (Expaxy)CARD (PS50209)   
Domains : Interpro (EBI)CARD    DEATH-like_dom_sf   
Domain families : Pfam (Sanger)CARD (PF00619)   
Domain families : Pfam (NCBI)pfam00619   
Conserved Domain (NCBI)CARD18
DMDM Disease mutations59082
Blocks (Seattle)CARD18
PDB (RSDB)1DGN   
PDB Europe1DGN   
PDB (PDBSum)1DGN   
PDB (IMB)1DGN   
Structural Biology KnowledgeBase1DGN   
SCOP (Structural Classification of Proteins)1DGN   
CATH (Classification of proteins structures)1DGN   
SuperfamilyP57730
Human Protein Atlas [tissue]ENSG00000255501-CARD18 [tissue]
Peptide AtlasP57730
HPRD16099
IPIIPI00027987   IPI00977920   
Protein Interaction databases
DIP (DOE-UCLA)P57730
IntAct (EBI)P57730
FunCoupENSG00000255501
BioGRIDCARD18
STRING (EMBL)CARD18
ZODIACCARD18
Ontologies - Pathways
QuickGOP57730
Ontology : AmiGOcysteine-type endopeptidase inhibitor activity  protein binding  inflammatory response  negative regulation of protein binding  protein-containing complex  protein-containing complex  regulation of apoptotic process  CARD domain binding  negative regulation of interleukin-1 beta secretion  negative regulation of interleukin-1 beta secretion  caspase binding  caspase binding  inhibition of cysteine-type endopeptidase activity  
Ontology : EGO-EBIcysteine-type endopeptidase inhibitor activity  protein binding  inflammatory response  negative regulation of protein binding  protein-containing complex  protein-containing complex  regulation of apoptotic process  CARD domain binding  negative regulation of interleukin-1 beta secretion  negative regulation of interleukin-1 beta secretion  caspase binding  caspase binding  inhibition of cysteine-type endopeptidase activity  
Pathways : KEGGNOD-like receptor signaling pathway   
NDEx NetworkCARD18
Atlas of Cancer Signalling NetworkCARD18
Wikipedia pathwaysCARD18
Orthology - Evolution
OrthoDB59082
GeneTree (enSembl)ENSG00000255501
Phylogenetic Trees/Animal Genes : TreeFamCARD18
HOGENOMP57730
Homologs : HomoloGeneCARD18
Homology/Alignments : Family Browser (UCSC)CARD18
Gene fusions - Rearrangements
Fusion : QuiverCARD18
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCARD18 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CARD18
dbVarCARD18
ClinVarCARD18
MonarchCARD18
1000_GenomesCARD18 
Exome Variant ServerCARD18
GNOMAD BrowserENSG00000255501
Varsome BrowserCARD18
Genetic variants : HAPMAP59082
Genomic Variants (DGV)CARD18 [DGVbeta]
DECIPHERCARD18 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCARD18 
Mutations
ICGC Data PortalCARD18 
TCGA Data PortalCARD18 
Broad Tumor PortalCARD18
OASIS PortalCARD18 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCARD18  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCARD18
Mutations and Diseases : HGMDCARD18
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CARD18
DgiDB (Drug Gene Interaction Database)CARD18
DoCM (Curated mutations)CARD18 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CARD18 (select a term)
intoGenCARD18
Cancer3DCARD18(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605354   
Orphanet
DisGeNETCARD18
MedgenCARD18
Genetic Testing Registry CARD18
NextProtP57730 [Medical]
TSGene59082
GENETestsCARD18
Target ValidationCARD18
Huge Navigator CARD18 [HugePedia]
snp3D : Map Gene to Disease59082
BioCentury BCIQCARD18
ClinGenCARD18
Clinical trials, drugs, therapy
Protein Interactions : CTD59082
Pharm GKB GenePA164717642
Clinical trialCARD18
Miscellaneous
canSAR (ICR)CARD18 (select the gene name)
HarmonizomeCARD18
DataMed IndexCARD18
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCARD18
EVEXCARD18
GoPubMedCARD18
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 14 14:04:19 CEST 2020
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