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CARD9 (caspase recruitment domain family member 9)

Identity

Alias_namescaspase recruitment domain family
Other aliasCANDF2
hCARD9
HGNC (Hugo) CARD9
LocusID (NCBI) 64170
Atlas_Id 43193
Location 9q34.3  [Link to chromosome band 9q34]
Location_base_pair Starts at 136363956 and ends at 136373681 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CARD9   16391
LRG (Locus Reference Genomic)LRG_178
Cards
Entrez_Gene (NCBI)CARD9  64170  caspase recruitment domain family member 9
AliasesCANDF2; hCARD9
GeneCards (Weizmann)CARD9
Ensembl hg19 (Hinxton)ENSG00000187796 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000187796 [Gene_View]  chr9:136363956-136373681 [Contig_View]  CARD9 [Vega]
ICGC DataPortalENSG00000187796
TCGA cBioPortalCARD9
AceView (NCBI)CARD9
Genatlas (Paris)CARD9
WikiGenes64170
SOURCE (Princeton)CARD9
Genetics Home Reference (NIH)CARD9
Genomic and cartography
GoldenPath hg38 (UCSC)CARD9  -     chr9:136363956-136373681 -  9q34.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CARD9  -     9q34.3   [Description]    (hg19-Feb_2009)
EnsemblCARD9 - 9q34.3 [CytoView hg19]  CARD9 - 9q34.3 [CytoView hg38]
Mapping of homologs : NCBICARD9 [Mapview hg19]  CARD9 [Mapview hg38]
OMIM212050   607212   
Gene and transcription
Genbank (Entrez)AF311287 AK024001 AK127481 AK292081 AK295647
RefSeq transcript (Entrez)NM_052813 NM_052814
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CARD9
Cluster EST : UnigeneHs.694071 [ NCBI ]
CGAP (NCI)Hs.694071
Alternative Splicing GalleryENSG00000187796
Gene ExpressionCARD9 [ NCBI-GEO ]   CARD9 [ EBI - ARRAY_EXPRESS ]   CARD9 [ SEEK ]   CARD9 [ MEM ]
Gene Expression Viewer (FireBrowse)CARD9 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64170
GTEX Portal (Tissue expression)CARD9
Human Protein AtlasENSG00000187796-CARD9 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H257   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H257  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H257
Splice isoforms : SwissVarQ9H257
PhosPhoSitePlusQ9H257
Domaine pattern : Prosite (Expaxy)CARD (PS50209)   
Domains : Interpro (EBI)CARD    DEATH-like_dom   
Domain families : Pfam (Sanger)CARD (PF00619)   
Domain families : Pfam (NCBI)pfam00619   
Conserved Domain (NCBI)CARD9
DMDM Disease mutations64170
Blocks (Seattle)CARD9
SuperfamilyQ9H257
Human Protein Atlas [tissue]ENSG00000187796-CARD9 [tissue]
Peptide AtlasQ9H257
HPRD06236
IPIIPI00641496   IPI00745573   IPI00827529   
Protein Interaction databases
DIP (DOE-UCLA)Q9H257
IntAct (EBI)Q9H257
FunCoupENSG00000187796
BioGRIDCARD9
STRING (EMBL)CARD9
ZODIACCARD9
Ontologies - Pathways
QuickGOQ9H257
Ontology : AmiGOstimulatory C-type lectin receptor signaling pathway  protein binding  cytoplasm  cytosol  plasma membrane  I-kappaB kinase/NF-kappaB signaling  response to fungus  response to peptidoglycan  response to muramyl dipeptide  positive regulation of interleukin-6 production  positive regulation of tumor necrosis factor production  positive regulation of stress-activated MAPK cascade  response to drug  regulation of tumor necrosis factor biosynthetic process  protein homodimerization activity  regulation of apoptotic process  positive regulation of I-kappaB kinase/NF-kappaB signaling  response to exogenous dsRNA  regulation of interleukin-2 biosynthetic process  innate immune response  regulation of interleukin-6 biosynthetic process  positive regulation of JNK cascade  CARD domain binding  defense response to Gram-positive bacterium  defense response to virus  
Ontology : EGO-EBIstimulatory C-type lectin receptor signaling pathway  protein binding  cytoplasm  cytosol  plasma membrane  I-kappaB kinase/NF-kappaB signaling  response to fungus  response to peptidoglycan  response to muramyl dipeptide  positive regulation of interleukin-6 production  positive regulation of tumor necrosis factor production  positive regulation of stress-activated MAPK cascade  response to drug  regulation of tumor necrosis factor biosynthetic process  protein homodimerization activity  regulation of apoptotic process  positive regulation of I-kappaB kinase/NF-kappaB signaling  response to exogenous dsRNA  regulation of interleukin-2 biosynthetic process  innate immune response  regulation of interleukin-6 biosynthetic process  positive regulation of JNK cascade  CARD domain binding  defense response to Gram-positive bacterium  defense response to virus  
Pathways : KEGGNOD-like receptor signaling pathway    Tuberculosis   
NDEx NetworkCARD9
Atlas of Cancer Signalling NetworkCARD9
Wikipedia pathwaysCARD9
Orthology - Evolution
OrthoDB64170
GeneTree (enSembl)ENSG00000187796
Phylogenetic Trees/Animal Genes : TreeFamCARD9
HOVERGENQ9H257
HOGENOMQ9H257
Homologs : HomoloGeneCARD9
Homology/Alignments : Family Browser (UCSC)CARD9
Gene fusions - Rearrangements
Tumor Fusion PortalCARD9
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCARD9 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CARD9
dbVarCARD9
ClinVarCARD9
1000_GenomesCARD9 
Exome Variant ServerCARD9
ExAC (Exome Aggregation Consortium)ENSG00000187796
GNOMAD BrowserENSG00000187796
Genetic variants : HAPMAP64170
Genomic Variants (DGV)CARD9 [DGVbeta]
DECIPHERCARD9 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCARD9 
Mutations
ICGC Data PortalCARD9 
TCGA Data PortalCARD9 
Broad Tumor PortalCARD9
OASIS PortalCARD9 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCARD9  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCARD9
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)**PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database
BioMutasearch CARD9
DgiDB (Drug Gene Interaction Database)CARD9
DoCM (Curated mutations)CARD9 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CARD9 (select a term)
intoGenCARD9
Cancer3DCARD9(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM212050    607212   
Orphanet23698   
DisGeNETCARD9
MedgenCARD9
Genetic Testing Registry CARD9
NextProtQ9H257 [Medical]
TSGene64170
GENETestsCARD9
Target ValidationCARD9
Huge Navigator CARD9 [HugePedia]
snp3D : Map Gene to Disease64170
BioCentury BCIQCARD9
ClinGenCARD9
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64170
Chemical/Pharm GKB GenePA26077
Clinical trialCARD9
Miscellaneous
canSAR (ICR)CARD9 (select the gene name)
Probes
Litterature
PubMed60 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCARD9
EVEXCARD9
GoPubMedCARD9
iHOPCARD9
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:05:58 CET 2017

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