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CASC4 (cancer susceptibility 4)

Identity

Alias_symbol (synonym)H63
DKFZp459F1927
Other alias
HGNC (Hugo) CASC4
LocusID (NCBI) 113201
Atlas_Id 40785
Location 15q15.3  [Link to chromosome band 15q15]
Location_base_pair Starts at 44288711 and ends at 44415761 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
BARD1 (2q35) / CASC4 (15q15.3)CASC4 (15q15.3) / CASC4 (15q15.3)CASC4 (15q15.3) / LINGO1 (15q24.3)
CASC4 (15q15.3) / SORD (15q21.1)CASC4 (15q15.3) / TGM5 (15q15.2)CASC4 15q15.3 / TGM5 15q15.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CASC4   24892
Cards
Entrez_Gene (NCBI)CASC4  113201  cancer susceptibility 4
AliasesH63
GeneCards (Weizmann)CASC4
Ensembl hg19 (Hinxton)ENSG00000166734 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000166734 [Gene_View]  chr15:44288711-44415761 [Contig_View]  CASC4 [Vega]
ICGC DataPortalENSG00000166734
TCGA cBioPortalCASC4
AceView (NCBI)CASC4
Genatlas (Paris)CASC4
WikiGenes113201
SOURCE (Princeton)CASC4
Genetics Home Reference (NIH)CASC4
Genomic and cartography
GoldenPath hg38 (UCSC)CASC4  -     chr15:44288711-44415761 +  15q15.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CASC4  -     15q15.3   [Description]    (hg19-Feb_2009)
EnsemblCASC4 - 15q15.3 [CytoView hg19]  CASC4 - 15q15.3 [CytoView hg38]
Mapping of homologs : NCBICASC4 [Mapview hg19]  CASC4 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF103804 AK022565 AK095068 AK098265 AK291026
RefSeq transcript (Entrez)NM_138423 NM_177974
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CASC4
Cluster EST : UnigeneHs.512867 [ NCBI ]
CGAP (NCI)Hs.512867
Alternative Splicing GalleryENSG00000166734
Gene ExpressionCASC4 [ NCBI-GEO ]   CASC4 [ EBI - ARRAY_EXPRESS ]   CASC4 [ SEEK ]   CASC4 [ MEM ]
Gene Expression Viewer (FireBrowse)CASC4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)113201
GTEX Portal (Tissue expression)CASC4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6P4E1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6P4E1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6P4E1
Splice isoforms : SwissVarQ6P4E1
PhosPhoSitePlusQ6P4E1
Domains : Interpro (EBI)CASC4    GOLM1/CASC4   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)CASC4
DMDM Disease mutations113201
Blocks (Seattle)CASC4
SuperfamilyQ6P4E1
Human Protein AtlasENSG00000166734
Peptide AtlasQ6P4E1
HPRD11018
IPIIPI00383014   IPI00304892   IPI00940961   IPI00167232   IPI00374590   
Protein Interaction databases
DIP (DOE-UCLA)Q6P4E1
IntAct (EBI)Q6P4E1
FunCoupENSG00000166734
BioGRIDCASC4
STRING (EMBL)CASC4
ZODIACCASC4
Ontologies - Pathways
QuickGOQ6P4E1
Ontology : AmiGOGolgi apparatus  integral component of membrane  
Ontology : EGO-EBIGolgi apparatus  integral component of membrane  
NDEx NetworkCASC4
Atlas of Cancer Signalling NetworkCASC4
Wikipedia pathwaysCASC4
Orthology - Evolution
OrthoDB113201
GeneTree (enSembl)ENSG00000166734
Phylogenetic Trees/Animal Genes : TreeFamCASC4
HOVERGENQ6P4E1
HOGENOMQ6P4E1
Homologs : HomoloGeneCASC4
Homology/Alignments : Family Browser (UCSC)CASC4
Gene fusions - Rearrangements
Fusion : MitelmanCASC4/TGM5 [15q15.3/15q15.2]  
Fusion: TCGACASC4 15q15.3 TGM5 15q15.2 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCASC4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CASC4
dbVarCASC4
ClinVarCASC4
1000_GenomesCASC4 
Exome Variant ServerCASC4
ExAC (Exome Aggregation Consortium)CASC4 (select the gene name)
Genetic variants : HAPMAP113201
Genomic Variants (DGV)CASC4 [DGVbeta]
DECIPHERCASC4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCASC4 
Mutations
ICGC Data PortalCASC4 
TCGA Data PortalCASC4 
Broad Tumor PortalCASC4
OASIS PortalCASC4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCASC4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCASC4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CASC4
DgiDB (Drug Gene Interaction Database)CASC4
DoCM (Curated mutations)CASC4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CASC4 (select a term)
intoGenCASC4
Cancer3DCASC4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenCASC4
Genetic Testing Registry CASC4
NextProtQ6P4E1 [Medical]
TSGene113201
GENETestsCASC4
Huge Navigator CASC4 [HugePedia]
snp3D : Map Gene to Disease113201
BioCentury BCIQCASC4
ClinGenCASC4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD113201
Chemical/Pharm GKB GenePA142672200
Clinical trialCASC4
Miscellaneous
canSAR (ICR)CASC4 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCASC4
EVEXCASC4
GoPubMedCASC4
iHOPCASC4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Fri May 19 12:08:55 CEST 2017

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