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CASK (calcium/calmodulin dependent serine protein kinase)

Identity

Alias (NCBI)CAGH39
CAMGUK
CMG
FGS4
LIN2
MICPCH
MRXSNA
TNRC8
hCASK
HGNC (Hugo) CASK
HGNC Alias symbLIN2
CAGH39
FGS4
HGNC Previous nameTNRC8
HGNC Previous nametrinucleotide repeat containing 8
 calcium/calmodulin-dependent serine protein kinase (MAGUK family)
LocusID (NCBI) 8573
Atlas_Id 43194
Location Xp11.4  [Link to chromosome band Xp11]
Location_base_pair Starts at 41514936 and ends at 41923034 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CASK (Xp11.4) / CASK (Xp11.4)CASK (Xp11.4) / COL24A1 (1p22.3)CASK (Xp11.4) / COX7A2 (6q14.1)
CASK (Xp11.4) / EYA2 (20q13.12)CASK (Xp11.4) / GLIPR1L1 (12q21.2)CASK (Xp11.4) / NPR2 (9p13.3)
EML4 (2p21) / CASK (Xp11.4)GRIP1 (12q14.3) / CASK (Xp11.4)LOC100507412 (-) / CASK (Xp11.4)
MESDC2 (15q25.1) / CASK (Xp11.4)TBL1X (Xp22.31) / CASK (Xp11.4)CASK Xp11.4 / EYA2 20q13.12
CASK Xp11.4 / GLIPR1L1 12q21.2EML4 2p21 / CASK Xp11.4TBL1X Xp22.31 / CASK Xp11.4

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Leukemias implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(X;15)(p11;q25) MESD/CASK
t(X;14)(p11.4;q32.33) IGH/GPR34

External links

Nomenclature
HGNC (Hugo)CASK   1497
Cards
Entrez_Gene (NCBI)CASK    calcium/calmodulin dependent serine protein kinase
AliasesCAGH39; CAMGUK; CMG; FGS4; 
LIN2; MICPCH; MRXSNA; TNRC8; hCASK
GeneCards (Weizmann)CASK
Ensembl hg19 (Hinxton)ENSG00000147044 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000147044 [Gene_View]  ENSG00000147044 [Sequence]  chrX:41514936-41923034 [Contig_View]  CASK [Vega]
ICGC DataPortalENSG00000147044
TCGA cBioPortalCASK
AceView (NCBI)CASK
Genatlas (Paris)CASK
SOURCE (Princeton)CASK
Genetics Home Reference (NIH)CASK
Genomic and cartography
GoldenPath hg38 (UCSC)CASK  -     chrX:41514936-41923034 -  Xp11.4   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CASK  -     Xp11.4   [Description]    (hg19-Feb_2009)
GoldenPathCASK - Xp11.4 [CytoView hg19]  CASK - Xp11.4 [CytoView hg38]
ImmunoBaseENSG00000147044
genome Data Viewer NCBICASK [Mapview hg19]  
OMIM300172   300422   300749   300908   
Gene and transcription
Genbank (Entrez)AB039327 AB208859 AF032119 AF035582 AF262404
RefSeq transcript (Entrez)NM_001126054 NM_001126055 NM_001367721 NM_003688
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CASK
Alternative Splicing GalleryENSG00000147044
Gene ExpressionCASK [ NCBI-GEO ]   CASK [ EBI - ARRAY_EXPRESS ]   CASK [ SEEK ]   CASK [ MEM ]
Gene Expression Viewer (FireBrowse)CASK [ Firebrowse - Broad ]
GenevisibleExpression of CASK in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8573
GTEX Portal (Tissue expression)CASK
Human Protein AtlasENSG00000147044-CASK [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)CASK
Blocks (Seattle)CASK
Human Protein Atlas [tissue]ENSG00000147044-CASK [tissue]
HPRD02164
IPIIPI00514301   IPI00555605   IPI00877929   IPI00937304   IPI00646452   IPI00641315   IPI00644270   IPI00877806   IPI01015842   
Protein Interaction databases
BioGRIDCASK
STRING (EMBL)CASK
ZODIACCASK
Ontologies - Pathways
Litterature
PubMed131 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCASK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 25 19:13:55 CET 2021
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