CASP12 (caspase 12 (gene/pseudogene))

2014-08-01  

Identity

HGNC
LOCATION
11q22.3
LOCUSID
ALIAS
CASP-12,CASP12P1
FUSION GENES

Other Information

Locus ID:

NCBI: 100506742
MIM: 608633
HGNC: 19004
Ensembl: ENSG00000204403

Variants:

dbSNP: 100506742
ClinVar: 100506742
TCGA: ENSG00000204403
COSMIC: CASP12

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000204403ENST00000417998Q6UXS9
ENSG00000204403ENST00000422698A0A384DVP2
ENSG00000204403ENST00000458137Q6UXS9

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9

Pathways

PathwaySourceExternal ID
ApoptosisKEGGko04210
Alzheimer's diseaseKEGGko05010
Amyotrophic lateral sclerosis (ALS)KEGGko05014
ApoptosisKEGGhsa04210
Alzheimer's diseaseKEGGhsa05010
Amyotrophic lateral sclerosis (ALS)KEGGhsa05014
Prion diseasesKEGGko05020
Prion diseasesKEGGhsa05020
NOD-like receptor signaling pathwayKEGGko04621
NOD-like receptor signaling pathwayKEGGhsa04621
Protein processing in endoplasmic reticulumKEGGko04141
Protein processing in endoplasmic reticulumKEGGhsa04141
Hepatitis BKEGGhsa05161

References

Pubmed IDYearTitleCitations
202993682010Examination of association with candidate genes for diabetic nephropathy in a Mexican American population.13
205770922010Genetic variation of innate immune genes in HIV-infected african patients with or without oropharyngeal candidiasis.13
262615842015ER stress related factor ATF6 and caspase-12 trigger apoptosis in neonatal hypoxic-ischemic encephalopathy.11
197217132009Caspase-12 and the inflammatory response to Yersinia pestis.10
200411822009The calpain, caspase 12, caspase 3 cascade leading to apoptosis is altered in F508del-CFTR expressing cells.10
175742102007Apoptosis induced by BIK was decreased with RNA interference of caspase-12.3
315578822019Common Nevus and Skin Cutaneous Melanoma: Prognostic Genes Identified by Gene Co-Expression Network Analysis.3
150337642003Na/Ca exchanger overexpression induces endoplasmic reticulum stress, caspase-12 release, and apoptosis.2
255033802014Caspase-12 silencing attenuates inhibitory effects of cigarette smoke extract on NOD1 signaling and hBDs expression in human oral mucosal epithelial cells.2
271303682016Calpain and Caspase-12 Expression in Lens Epithelial Cells of Diabetic Cataracts.2

Citation

Dessen P

CASP12 (caspase 12 (gene/pseudogene))

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54191/casp12