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CASP2 (caspase 2)

Identity

Alias (NCBI)CASP-2
ICH1
NEDD-2
NEDD2
PPP1R57
HGNC (Hugo) CASP2
HGNC Alias symbICH1
PPP1R57
MGC2181
HGNC Alias nameprotein phosphatase 1, regulatory subunit 57
HGNC Previous nameNEDD2
HGNC Previous nameneural precursor cell expressed, developmentally down-regulated 2
 caspase 2, apoptosis-related cysteine peptidase
LocusID (NCBI) 835
Atlas_Id 919
Location 7q34  [Link to chromosome band 7q34]
Location_base_pair Starts at 143288351 and ends at 143307696 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CASP2 (7q34) / ADAR (1q21.3)CASP2 (7q34) / CASP2 (7q34)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  T-cell/histiocyte rich large B-cell lymphoma


External links

Nomenclature
HGNC (Hugo)CASP2   1503
Cards
Entrez_Gene (NCBI)CASP2    caspase 2
AliasesCASP-2; ICH1; NEDD-2; NEDD2; 
PPP1R57
GeneCards (Weizmann)CASP2
Ensembl hg19 (Hinxton)ENSG00000106144 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000106144 [Gene_View]  ENSG00000106144 [Sequence]  chr7:143288351-143307696 [Contig_View]  CASP2 [Vega]
ICGC DataPortalENSG00000106144
TCGA cBioPortalCASP2
AceView (NCBI)CASP2
Genatlas (Paris)CASP2
SOURCE (Princeton)CASP2
Genetics Home Reference (NIH)CASP2
Genomic and cartography
GoldenPath hg38 (UCSC)CASP2  -     chr7:143288351-143307696 +  7q34   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CASP2  -     7q34   [Description]    (hg19-Feb_2009)
GoldenPathCASP2 - 7q34 [CytoView hg19]  CASP2 - 7q34 [CytoView hg38]
ImmunoBaseENSG00000106144
genome Data Viewer NCBICASP2 [Mapview hg19]  
OMIM600639   
Gene and transcription
Genbank (Entrez)AB209640 AF314174 AF314175 AK096245 AK291274
RefSeq transcript (Entrez)NM_001224 NM_032982 NM_032983
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CASP2
Alternative Splicing GalleryENSG00000106144
Gene ExpressionCASP2 [ NCBI-GEO ]   CASP2 [ EBI - ARRAY_EXPRESS ]   CASP2 [ SEEK ]   CASP2 [ MEM ]
Gene Expression Viewer (FireBrowse)CASP2 [ Firebrowse - Broad ]
GenevisibleExpression of CASP2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)835
GTEX Portal (Tissue expression)CASP2
Human Protein AtlasENSG00000106144-CASP2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)CASP2
Blocks (Seattle)CASP2
Human Protein Atlas [tissue]ENSG00000106144-CASP2 [tissue]
HPRD02800
IPIIPI00291570   IPI00216410   IPI00953479   IPI00917270   IPI00018345   
Protein Interaction databases
BioGRIDCASP2
STRING (EMBL)CASP2
ZODIACCASP2
Ontologies - Pathways
Litterature
PubMed177 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCASP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 25 19:13:55 CET 2021

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