Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 839
MIM: 601532
HGNC: 1507
Ensembl: ENSG00000138794
Variants:
dbSNP: 839
ClinVar: 839
TCGA: ENSG00000138794
COSMIC: CASP6
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000138794 | ENST00000265164 | P55212 |
| ENSG00000138794 | ENST00000352981 | P55212 |
| ENSG00000138794 | ENST00000503684 | D6RHU3 |
| ENSG00000138794 | ENST00000505486 | D6RBM3 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38967580 | 2024 | NUAK1 promotes metabolic dysfunction-associated steatohepatitis progression by activating Caspase 6-driven pyroptosis and inflammation. | 0 |
| 38967580 | 2024 | NUAK1 promotes metabolic dysfunction-associated steatohepatitis progression by activating Caspase 6-driven pyroptosis and inflammation. | 0 |
| 36814103 | 2023 | Caspase-6 is a key regulator of cross-talk signal way in PANoptosis in cancer. | 8 |
| 36882663 | 2023 | Dissection of pyroptosis-related prognostic signature and CASP6-mediated regulation in pancreatic adenocarcinoma: new sights to clinical decision-making. | 1 |
| 37070911 | 2023 | Role of cited-1 and caspase-6 expression in HELLP syndrome. | 0 |
| 37828624 | 2023 | Caspase 6 promotes innate immune activation by functional crosstalk between RIPK1-IκBα axis in liver inflammation. | 1 |
| 36814103 | 2023 | Caspase-6 is a key regulator of cross-talk signal way in PANoptosis in cancer. | 8 |
| 36882663 | 2023 | Dissection of pyroptosis-related prognostic signature and CASP6-mediated regulation in pancreatic adenocarcinoma: new sights to clinical decision-making. | 1 |
| 37070911 | 2023 | Role of cited-1 and caspase-6 expression in HELLP syndrome. | 0 |
| 37828624 | 2023 | Caspase 6 promotes innate immune activation by functional crosstalk between RIPK1-IκBα axis in liver inflammation. | 1 |
| 33649324 | 2021 | Caspase-6-cleaved Tau fails to induce Tau hyperphosphorylation and aggregation, neurodegeneration, glial inflammation, and cognitive deficits. | 8 |
| 34135352 | 2021 | Rare CASP6N73T variant associated with hippocampal volume exhibits decreased proteolytic activity, synaptic transmission defect, and neurodegeneration. | 5 |
| 33649324 | 2021 | Caspase-6-cleaved Tau fails to induce Tau hyperphosphorylation and aggregation, neurodegeneration, glial inflammation, and cognitive deficits. | 8 |
| 34135352 | 2021 | Rare CASP6N73T variant associated with hippocampal volume exhibits decreased proteolytic activity, synaptic transmission defect, and neurodegeneration. | 5 |
| 30420425 | 2019 | Tri-arginine exosite patch of caspase-6 recruits substrates for hydrolysis. | 12 |
Citation
Dessen P
CASP6 (caspase 6)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/923/casp6
