Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CAT (catalase)

Identity

Other names-
HGNC (Hugo) CAT
LocusID (NCBI) 847
Location 11p13
Location_base_pair Starts at 34460472 and ends at 34493607 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CAT   1516
Cards
Entrez_Gene (NCBI)CAT  847  catalase
GeneCards (Weizmann)CAT
Ensembl (Hinxton)ENSG00000121691 [Gene_View]  chr11:34460472-34493607 [Contig_View]  CAT [Vega]
ICGC DataPortalENSG00000121691
cBioPortalCAT
AceView (NCBI)CAT
Genatlas (Paris)CAT
WikiGenes847
SOURCE (Princeton)NM_001752
Genomic and cartography
GoldenPath (UCSC)CAT  -  11p13   chr11:34460472-34493607 +  11p13   [Description]    (hg19-Feb_2009)
EnsemblCAT - 11p13 [CytoView]
Mapping of homologs : NCBICAT [Mapview]
OMIM115500   614097   
Gene and transcription
Genbank (Entrez)AK291585 AK301577 AK310184 AK315350 AW023382
RefSeq transcript (Entrez)NM_001752
RefSeq genomic (Entrez)AC_000143 NC_000011 NC_018922 NG_013339 NT_009237 NW_001838022 NW_004929378
Consensus coding sequences : CCDS (NCBI)CAT
Cluster EST : UnigeneHs.502302 [ NCBI ]
CGAP (NCI)Hs.502302
Alternative Splicing : Fast-db (Paris)GSHG0004749
Alternative Splicing GalleryENSG00000121691
Gene ExpressionCAT [ NCBI-GEO ]     CAT [ SEEK ]   CAT [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP04040 (Uniprot)
NextProtP04040  [Medical]
With graphics : InterProP04040
Splice isoforms : SwissVarP04040 (Swissvar)
Domaine pattern : Prosite (Expaxy)CATALASE_1 (PS00437)    CATALASE_2 (PS00438)    CATALASE_3 (PS51402)   
Domains : Interpro (EBI)Catalase [organisation]   Catalase-like_dom [organisation]   Catalase_AS [organisation]   Catalase_clade1/3 [organisation]   Catalase_core [organisation]   Catalase_haem_BS [organisation]   Catalase_immune_responsive [organisation]  
Related proteins : CluSTrP04040
Domain families : Pfam (Sanger)Catalase (PF00199)    Catalase-rel (PF06628)   
Domain families : Pfam (NCBI)pfam00199    pfam06628   
Domain families : Smart (EMBL)Catalase (SM01060)  
DMDM Disease mutations847
Blocks (Seattle)P04040
PDB (SRS)1DGB    1DGF    1DGG    1DGH    1F4J    1QQW   
PDB (PDBSum)1DGB    1DGF    1DGG    1DGH    1F4J    1QQW   
PDB (IMB)1DGB    1DGF    1DGG    1DGH    1F4J    1QQW   
PDB (RSDB)1DGB    1DGF    1DGG    1DGH    1F4J    1QQW   
Human Protein AtlasENSG00000121691 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasP04040
HPRD00282
IPIIPI00465436   
Protein Interaction databases
DIP (DOE-UCLA)P04040
IntAct (EBI)P04040
FunCoupENSG00000121691
BioGRIDCAT
InParanoidP04040
Interologous Interaction database P04040
IntegromeDBCAT
STRING (EMBL)CAT
Ontologies - Pathways
Ontology : AmiGOresponse to reactive oxygen species  osteoblast differentiation  ureteric bud development  response to hypoxia  kidney development  aminoacylase activity  catalase activity  catalase activity  receptor binding  mitochondrial intermembrane space  lysosome  peroxisome  peroxisomal membrane  peroxisomal matrix  endoplasmic reticulum  Golgi apparatus  cytosol  plasma membrane  purine nucleobase metabolic process  purine nucleotide catabolic process  triglyceride metabolic process  cholesterol metabolic process  aerobic respiration  UV protection  positive regulation of phosphatidylinositol 3-kinase signaling  membrane  antioxidant activity  oxidoreductase activity, acting on peroxide as acceptor  enzyme binding  hemoglobin metabolic process  heme binding  negative regulation of NF-kappaB transcription factor activity  response to vitamin E  menopause  hydrogen peroxide catabolic process  protein homodimerization activity  negative regulation of apoptotic process  intracellular membrane-bounded organelle  small molecule metabolic process  metal ion binding  NADP binding  positive regulation of NF-kappaB transcription factor activity  protein tetramerization  protein homotetramerization  positive regulation of cell division  nucleobase-containing small molecule metabolic process  response to hyperoxia  extracellular vesicular exosome  cellular response to growth factor stimulus  
Ontology : EGO-EBIresponse to reactive oxygen species  osteoblast differentiation  ureteric bud development  response to hypoxia  kidney development  aminoacylase activity  catalase activity  catalase activity  receptor binding  mitochondrial intermembrane space  lysosome  peroxisome  peroxisomal membrane  peroxisomal matrix  endoplasmic reticulum  Golgi apparatus  cytosol  plasma membrane  purine nucleobase metabolic process  purine nucleotide catabolic process  triglyceride metabolic process  cholesterol metabolic process  aerobic respiration  UV protection  positive regulation of phosphatidylinositol 3-kinase signaling  membrane  antioxidant activity  oxidoreductase activity, acting on peroxide as acceptor  enzyme binding  hemoglobin metabolic process  heme binding  negative regulation of NF-kappaB transcription factor activity  response to vitamin E  menopause  hydrogen peroxide catabolic process  protein homodimerization activity  negative regulation of apoptotic process  intracellular membrane-bounded organelle  small molecule metabolic process  metal ion binding  NADP binding  positive regulation of NF-kappaB transcription factor activity  protein tetramerization  protein homotetramerization  positive regulation of cell division  nucleobase-containing small molecule metabolic process  response to hyperoxia  extracellular vesicular exosome  cellular response to growth factor stimulus  
Pathways : BIOCARTAThe IGF-1 Receptor and Longevity [Genes]   
Pathways : KEGGTryptophan metabolism    Glyoxylate and dicarboxylate metabolism    FoxO signaling pathway    Peroxisome    Amyotrophic lateral sclerosis (ALS)   
Protein Interaction DatabaseCAT
Wikipedia pathwaysCAT
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)CAT
snp3D : Map Gene to Disease847
SNP (GeneSNP Utah)CAT
SNP : HGBaseCAT
Genetic variants : HAPMAPCAT
Exome VariantCAT
1000_GenomesCAT 
ICGC programENSG00000121691 
Somatic Mutations in Cancer : COSMICCAT 
CONAN: Copy Number AnalysisCAT 
Mutations and Diseases : HGMDCAT
Genomic VariantsCAT  CAT [DGVbeta]
dbVarCAT
ClinVarCAT
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM115500    614097   
MedgenCAT
GENETestsCAT
Disease Genetic AssociationCAT
Huge Navigator CAT [HugePedia]  CAT [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneCAT
Homology/Alignments : Family Browser (UCSC)CAT
Phylogenetic Trees/Animal Genes : TreeFamCAT
Chemical/Protein Interactions : CTD847
Chemical/Pharm GKB GenePA26099
Clinical trialCAT
Cancer Resource (Charite)ENSG00000121691
Other databases
Probes
Litterature
PubMed269 Pubmed reference(s) in Entrez
CoreMineCAT
iHOPCAT
OncoSearchCAT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jul 30 13:46:25 CEST 2014

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jlhuret@AtlasGeneticsOncology.org.