CAV2 (caveolin 2)

2003-11-01  

Identity

HGNC
LOCATION
7q31.2
LOCUSID
ALIAS
CAV
FUSION GENES

Other Information

Locus ID:

NCBI: 858
MIM: 601048
HGNC: 1528
Ensembl: ENSG00000105971

Variants:

dbSNP: 858
ClinVar: 858
TCGA: ENSG00000105971
COSMIC: CAV2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105971ENST00000222693P51636
ENSG00000105971ENST00000222693Q53X57
ENSG00000105971ENST00000343213P51636
ENSG00000105971ENST00000393480E9PCT3

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Focal adhesionKEGGko04510
Focal adhesionKEGGhsa04510
EndocytosisKEGGko04144
EndocytosisKEGGhsa04144
Bacterial invasion of epithelial cellsKEGGko05100
Bacterial invasion of epithelial cellsKEGGhsa05100
Proteoglycans in cancerKEGGhsa05205
Proteoglycans in cancerKEGGko05205
Fluid shear stress and atherosclerosisKEGGko05418
Fluid shear stress and atherosclerosisKEGGhsa05418

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
200620602010Genome-wide association study of PR interval.185
208352382010Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma.156
208352382010Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma.156
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
218736082011Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma in Caucasians from the USA.83
157032042005Maxi-K channels localize to caveolae in human myometrium: a role for an actin-channel-caveolin complex in the regulation of myometrial smooth muscle K+ current.45
245726742014Association of CAV1/CAV2 genomic variants with primary open-angle glaucoma overall and by gender and pattern of visual field loss.39
155693062004D1 dopamine receptor signaling involves caveolin-2 in HEK-293 cells.38
128134622003Peroxisome proliferator-activated receptor-gamma upregulates caveolin-1 and caveolin-2 expression in human carcinoma cells.33
162447902006Overexpression of caveolin-1 and -2 in cell lines and in human samples of inflammatory breast cancer.33

Citation

Dessen P

CAV2 (caveolin 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/933/cav2