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CBX2 (chromobox 2)

Identity

Alias_namesCDCA6
chromobox homolog 2 (Drosophila Pc class)
cell division cycle associated 6
chromobox homolog 2
Alias_symbol (synonym)MGC10561
Other aliasM33
SRXY5
HGNC (Hugo) CBX2
LocusID (NCBI) 84733
Atlas_Id 54967
Location 17q25.3  [Link to chromosome band 17q25]
Location_base_pair Starts at 79778178 and ends at 79787650 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
OGG1 (3p25.3) / CBX2 (17q25.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CBX2   1552
Cards
Entrez_Gene (NCBI)CBX2  84733  chromobox 2
AliasesCDCA6; M33; SRXY5
GeneCards (Weizmann)CBX2
Ensembl hg19 (Hinxton)ENSG00000173894 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173894 [Gene_View]  chr17:79778178-79787650 [Contig_View]  CBX2 [Vega]
ICGC DataPortalENSG00000173894
TCGA cBioPortalCBX2
AceView (NCBI)CBX2
Genatlas (Paris)CBX2
WikiGenes84733
SOURCE (Princeton)CBX2
Genetics Home Reference (NIH)CBX2
Genomic and cartography
GoldenPath hg38 (UCSC)CBX2  -     chr17:79778178-79787650 +  17q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CBX2  -     17q25.3   [Description]    (hg19-Feb_2009)
EnsemblCBX2 - 17q25.3 [CytoView hg19]  CBX2 - 17q25.3 [CytoView hg38]
Mapping of homologs : NCBICBX2 [Mapview hg19]  CBX2 [Mapview hg38]
OMIM602770   613080   
Gene and transcription
Genbank (Entrez)AL157459 BC004252 BC119759 BC119760 BC156118
RefSeq transcript (Entrez)NM_005189 NM_032647
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CBX2
Cluster EST : UnigeneHs.368410 [ NCBI ]
CGAP (NCI)Hs.368410
Alternative Splicing GalleryENSG00000173894
Gene ExpressionCBX2 [ NCBI-GEO ]   CBX2 [ EBI - ARRAY_EXPRESS ]   CBX2 [ SEEK ]   CBX2 [ MEM ]
Gene Expression Viewer (FireBrowse)CBX2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84733
GTEX Portal (Tissue expression)CBX2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14781   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14781  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14781
Splice isoforms : SwissVarQ14781
PhosPhoSitePlusQ14781
Domaine pattern : Prosite (Expaxy)CHROMO_1 (PS00598)    CHROMO_2 (PS50013)   
Domains : Interpro (EBI)CBX7_C    Chromo/chromo_shadow_dom    Chromo_domain    Chromodomain-like    Chromodomain_CS   
Domain families : Pfam (Sanger)CBX7_C (PF17218)    Chromo (PF00385)   
Domain families : Pfam (NCBI)pfam17218    pfam00385   
Domain families : Smart (EMBL)CHROMO (SM00298)  
Conserved Domain (NCBI)CBX2
DMDM Disease mutations84733
Blocks (Seattle)CBX2
PDB (SRS)2D9U    3H91    5EPK   
PDB (PDBSum)2D9U    3H91    5EPK   
PDB (IMB)2D9U    3H91    5EPK   
PDB (RSDB)2D9U    3H91    5EPK   
Structural Biology KnowledgeBase2D9U    3H91    5EPK   
SCOP (Structural Classification of Proteins)2D9U    3H91    5EPK   
CATH (Classification of proteins structures)2D9U    3H91    5EPK   
SuperfamilyQ14781
Human Protein AtlasENSG00000173894
Peptide AtlasQ14781
HPRD14397
IPIIPI00651642   IPI00013321   
Protein Interaction databases
DIP (DOE-UCLA)Q14781
IntAct (EBI)Q14781
FunCoupENSG00000173894
BioGRIDCBX2
STRING (EMBL)CBX2
ZODIACCBX2
Ontologies - Pathways
QuickGOQ14781
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  euchromatin  heterochromatin  DNA binding  chromatin binding  protein binding  nucleus  nucleoplasm  nucleoplasm  transcription, DNA-templated  covalent chromatin modification  cell differentiation  PcG protein complex  methylated histone binding  PRC1 complex  development of primary sexual characteristics  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  euchromatin  heterochromatin  DNA binding  chromatin binding  protein binding  nucleus  nucleoplasm  nucleoplasm  transcription, DNA-templated  covalent chromatin modification  cell differentiation  PcG protein complex  methylated histone binding  PRC1 complex  development of primary sexual characteristics  
NDEx NetworkCBX2
Atlas of Cancer Signalling NetworkCBX2
Wikipedia pathwaysCBX2
Orthology - Evolution
OrthoDB84733
GeneTree (enSembl)ENSG00000173894
Phylogenetic Trees/Animal Genes : TreeFamCBX2
HOVERGENQ14781
HOGENOMQ14781
Homologs : HomoloGeneCBX2
Homology/Alignments : Family Browser (UCSC)CBX2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCBX2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CBX2
dbVarCBX2
ClinVarCBX2
1000_GenomesCBX2 
Exome Variant ServerCBX2
ExAC (Exome Aggregation Consortium)CBX2 (select the gene name)
Genetic variants : HAPMAP84733
Genomic Variants (DGV)CBX2 [DGVbeta]
DECIPHERCBX2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCBX2 
Mutations
ICGC Data PortalCBX2 
TCGA Data PortalCBX2 
Broad Tumor PortalCBX2
OASIS PortalCBX2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCBX2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCBX2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CBX2
DgiDB (Drug Gene Interaction Database)CBX2
DoCM (Curated mutations)CBX2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CBX2 (select a term)
intoGenCBX2
Cancer3DCBX2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602770    613080   
Orphanet1044   
MedgenCBX2
Genetic Testing Registry CBX2
NextProtQ14781 [Medical]
TSGene84733
GENETestsCBX2
Target ValidationCBX2
Huge Navigator CBX2 [HugePedia]
snp3D : Map Gene to Disease84733
BioCentury BCIQCBX2
ClinGenCBX2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84733
Chemical/Pharm GKB GenePA26127
Clinical trialCBX2
Miscellaneous
canSAR (ICR)CBX2 (select the gene name)
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCBX2
EVEXCBX2
GoPubMedCBX2
iHOPCBX2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:26:53 CEST 2017

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