Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23466
MIM: 617438
HGNC: 1556
Ensembl: ENSG00000183741
Variants:
dbSNP: 23466
ClinVar: 23466
TCGA: ENSG00000183741
COSMIC: CBX6
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000183741 | ENST00000216083 | B0QXZ6 |
| ENSG00000183741 | ENST00000407418 | O95503 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Cellular responses to stress | REACTOME | R-HSA-2262752 |
| Cellular Senescence | REACTOME | R-HSA-2559583 |
| Oxidative Stress Induced Senescence | REACTOME | R-HSA-2559580 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33028834 | 2020 | Proteasomal degradation of polycomb-group protein CBX6 confers MMP-2 expression essential for mesothelioma invasion. | 7 |
| 33028834 | 2020 | Proteasomal degradation of polycomb-group protein CBX6 confers MMP-2 expression essential for mesothelioma invasion. | 7 |
| 30655550 | 2019 | CBX6 is negatively regulated by EZH2 and plays a potential tumor suppressor role in breast cancer. | 24 |
| 30655550 | 2019 | CBX6 is negatively regulated by EZH2 and plays a potential tumor suppressor role in breast cancer. | 24 |
| 28122351 | 2017 | CBX6 overexpression contributes to tumor progression and is predictive of a poor prognosis in hepatocellular carcinoma. | 30 |
| 28839133 | 2017 | USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components. | 19 |
| 28122351 | 2017 | CBX6 overexpression contributes to tumor progression and is predictive of a poor prognosis in hepatocellular carcinoma. | 30 |
| 28839133 | 2017 | USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components. | 19 |
| 26343356 | 2015 | Polycomb genes are associated with response to imatinib in chronic myeloid leukemia. | 8 |
| 26343356 | 2015 | Polycomb genes are associated with response to imatinib in chronic myeloid leukemia. | 8 |
Citation
Dessen P
CBX6 (chromobox 6)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47138/cbx6
