Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CBX8 (chromobox 8)

Identity

Alias_nameschromobox homolog 8 (Drosophila Pc class)
chromobox homolog 8
Alias_symbol (synonym)RC1
HPC3
PC3
Other alias
HGNC (Hugo) CBX8
LocusID (NCBI) 57332
Atlas_Id 46977
Location 17q25.3  [Link to chromosome band 17q25]
Location_base_pair Starts at 77768176 and ends at 77770915 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CBX8   15962
Cards
Entrez_Gene (NCBI)CBX8  57332  chromobox 8
AliasesPC3; RC1
GeneCards (Weizmann)CBX8
Ensembl hg19 (Hinxton)ENSG00000141570 [Gene_View]  chr17:77768176-77770915 [Contig_View]  CBX8 [Vega]
Ensembl hg38 (Hinxton)ENSG00000141570 [Gene_View]  chr17:77768176-77770915 [Contig_View]  CBX8 [Vega]
ICGC DataPortalENSG00000141570
TCGA cBioPortalCBX8
AceView (NCBI)CBX8
Genatlas (Paris)CBX8
WikiGenes57332
SOURCE (Princeton)CBX8
Genetics Home Reference (NIH)CBX8
Genomic and cartography
GoldenPath hg19 (UCSC)CBX8  -     chr17:77768176-77770915 -  17q25.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CBX8  -     17q25.3   [Description]    (hg38-Dec_2013)
EnsemblCBX8 - 17q25.3 [CytoView hg19]  CBX8 - 17q25.3 [CytoView hg38]
Mapping of homologs : NCBICBX8 [Mapview hg19]  CBX8 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF174482 AF266479 AK074560 BC008937 BC009376
RefSeq transcript (Entrez)NM_020649
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010783 NW_004929407
Consensus coding sequences : CCDS (NCBI)CBX8
Cluster EST : UnigeneHs.387258 [ NCBI ]
CGAP (NCI)Hs.387258
Alternative Splicing GalleryENSG00000141570
Gene ExpressionCBX8 [ NCBI-GEO ]   CBX8 [ EBI - ARRAY_EXPRESS ]   CBX8 [ SEEK ]   CBX8 [ MEM ]
Gene Expression Viewer (FireBrowse)CBX8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57332
GTEX Portal (Tissue expression)CBX8
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HC52   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HC52  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HC52
Splice isoforms : SwissVarQ9HC52
PhosPhoSitePlusQ9HC52
Domaine pattern : Prosite (Expaxy)CHROMO_1 (PS00598)    CHROMO_2 (PS50013)   
Domains : Interpro (EBI)Chromo/shadow_dom    Chromo_domain    Chromodomain-like    Chromodomain_CS   
Domain families : Pfam (Sanger)Chromo (PF00385)   
Domain families : Pfam (NCBI)pfam00385   
Domain families : Smart (EMBL)CHROMO (SM00298)  
Conserved Domain (NCBI)CBX8
DMDM Disease mutations57332
Blocks (Seattle)CBX8
PDB (SRS)3I91    5EQ0   
PDB (PDBSum)3I91    5EQ0   
PDB (IMB)3I91    5EQ0   
PDB (RSDB)3I91    5EQ0   
Structural Biology KnowledgeBase3I91    5EQ0   
SCOP (Structural Classification of Proteins)3I91    5EQ0   
CATH (Classification of proteins structures)3I91    5EQ0   
SuperfamilyQ9HC52
Human Protein AtlasENSG00000141570
Peptide AtlasQ9HC52
HPRD13006
IPIIPI00307659   IPI00878493   IPI00878943   
Protein Interaction databases
DIP (DOE-UCLA)Q9HC52
IntAct (EBI)Q9HC52
FunCoupENSG00000141570
BioGRIDCBX8
STRING (EMBL)CBX8
ZODIACCBX8
Ontologies - Pathways
QuickGOQ9HC52
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  nuclear chromatin  heterochromatin  single-stranded RNA binding  protein binding  nucleus  nucleoplasm  nucleoplasm  transcription, DNA-templated  positive regulation of cell proliferation  histone ubiquitination  protein sumoylation  PcG protein complex  positive regulation of collagen biosynthetic process  methylated histone binding  PRC1 complex  positive regulation of DNA repair  regulation of catalytic activity  cellular response to hydrogen peroxide  ubiquitin-protein transferase activator activity  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  nuclear chromatin  heterochromatin  single-stranded RNA binding  protein binding  nucleus  nucleoplasm  nucleoplasm  transcription, DNA-templated  positive regulation of cell proliferation  histone ubiquitination  protein sumoylation  PcG protein complex  positive regulation of collagen biosynthetic process  methylated histone binding  PRC1 complex  positive regulation of DNA repair  regulation of catalytic activity  cellular response to hydrogen peroxide  ubiquitin-protein transferase activator activity  
NDEx NetworkCBX8
Atlas of Cancer Signalling NetworkCBX8
Wikipedia pathwaysCBX8
Orthology - Evolution
OrthoDB57332
GeneTree (enSembl)ENSG00000141570
Phylogenetic Trees/Animal Genes : TreeFamCBX8
HOVERGENQ9HC52
HOGENOMQ9HC52
Homologs : HomoloGeneCBX8
Homology/Alignments : Family Browser (UCSC)CBX8
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCBX8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CBX8
dbVarCBX8
ClinVarCBX8
1000_GenomesCBX8 
Exome Variant ServerCBX8
ExAC (Exome Aggregation Consortium)CBX8 (select the gene name)
Genetic variants : HAPMAP57332
Genomic Variants (DGV)CBX8 [DGVbeta]
DECIPHER (Syndromes)17:77768176-77770915  ENSG00000141570
CONAN: Copy Number AnalysisCBX8 
Mutations
ICGC Data PortalCBX8 
TCGA Data PortalCBX8 
Broad Tumor PortalCBX8
OASIS PortalCBX8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCBX8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCBX8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CBX8
DgiDB (Drug Gene Interaction Database)CBX8
DoCM (Curated mutations)CBX8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CBX8 (select a term)
intoGenCBX8
Cancer3DCBX8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenCBX8
Genetic Testing Registry CBX8
NextProtQ9HC52 [Medical]
TSGene57332
GENETestsCBX8
Huge Navigator CBX8 [HugePedia]
snp3D : Map Gene to Disease57332
BioCentury BCIQCBX8
ClinGenCBX8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57332
Chemical/Pharm GKB GenePA26133
Clinical trialCBX8
Miscellaneous
canSAR (ICR)CBX8 (select the gene name)
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCBX8
EVEXCBX8
GoPubMedCBX8
iHOPCBX8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 14:55:11 CEST 2017

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