Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CBY1 (chibby family member 1, beta catenin antagonist)

Identity

Alias_namesC22orf2
PGEA1
chromosome 22 open reading frame 2
PKD2 interactor, golgi and endoplasmic reticulum associated 1
chibby homolog 1 (Drosophila)
Alias_symbol (synonym)PIGEA14
PIGEA-14
Chibby
Cby
Other aliasCBY
HS508I15A
arb1
HGNC (Hugo) CBY1
LocusID (NCBI) 25776
Atlas_Id 42946
Location 22q13.1  [Link to chromosome band 22q13]
Location_base_pair Starts at 38656653 and ends at 38673851 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AKR1A1 (1p34.1) / CBY1 (22q13.1)EMID1 (22q12.2) / CBY1 (22q13.1)EMID1 22q12.2 / CBY1 22q13.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CBY1   1307
Cards
Entrez_Gene (NCBI)CBY1  25776  chibby family member 1, beta catenin antagonist
AliasesC22orf2; CBY; HS508I15A; PGEA1; 
PIGEA-14; PIGEA14; arb1
GeneCards (Weizmann)CBY1
Ensembl hg19 (Hinxton)ENSG00000100211 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100211 [Gene_View]  chr22:38656653-38673851 [Contig_View]  CBY1 [Vega]
ICGC DataPortalENSG00000100211
TCGA cBioPortalCBY1
AceView (NCBI)CBY1
Genatlas (Paris)CBY1
WikiGenes25776
SOURCE (Princeton)CBY1
Genetics Home Reference (NIH)CBY1
Genomic and cartography
GoldenPath hg38 (UCSC)CBY1  -     chr22:38656653-38673851 +  22q13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CBY1  -     22q13.1   [Description]    (hg19-Feb_2009)
EnsemblCBY1 - 22q13.1 [CytoView hg19]  CBY1 - 22q13.1 [CytoView hg38]
Mapping of homologs : NCBICBY1 [Mapview hg19]  CBY1 [Mapview hg38]
OMIM607757   
Gene and transcription
Genbank (Entrez)AB015347 AB111855 AF331041 AK307265 AK311928
RefSeq transcript (Entrez)NM_001002880 NM_015373
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CBY1
Cluster EST : UnigeneHs.744261 [ NCBI ]
CGAP (NCI)Hs.744261
Alternative Splicing GalleryENSG00000100211
Gene ExpressionCBY1 [ NCBI-GEO ]   CBY1 [ EBI - ARRAY_EXPRESS ]   CBY1 [ SEEK ]   CBY1 [ MEM ]
Gene Expression Viewer (FireBrowse)CBY1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)25776
GTEX Portal (Tissue expression)CBY1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y3M2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y3M2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y3M2
Splice isoforms : SwissVarQ9Y3M2
PhosPhoSitePlusQ9Y3M2
Domains : Interpro (EBI)Chibby_fam   
Domain families : Pfam (Sanger)Chibby (PF14645)   
Domain families : Pfam (NCBI)pfam14645   
Conserved Domain (NCBI)CBY1
DMDM Disease mutations25776
Blocks (Seattle)CBY1
PDB (SRS)4WRQ   
PDB (PDBSum)4WRQ   
PDB (IMB)4WRQ   
PDB (RSDB)4WRQ   
Structural Biology KnowledgeBase4WRQ   
SCOP (Structural Classification of Proteins)4WRQ   
CATH (Classification of proteins structures)4WRQ   
SuperfamilyQ9Y3M2
Human Protein AtlasENSG00000100211
Peptide AtlasQ9Y3M2
HPRD09676
IPIIPI00022269   IPI00879021   IPI00879866   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y3M2
IntAct (EBI)Q9Y3M2
FunCoupENSG00000100211
BioGRIDCBY1
STRING (EMBL)CBY1
ZODIACCBY1
Ontologies - Pathways
QuickGOQ9Y3M2
Ontology : AmiGOprotein binding  nucleus  nucleoplasm  trans-Golgi network  centriole  cytosol  beta-catenin binding  beta-catenin binding  protein localization  nuclear speck  negative regulation of Wnt signaling pathway  identical protein binding  protein homodimerization activity  fat cell differentiation  negative regulation of transcription, DNA-templated  protein homotetramerization  cardiac muscle cell differentiation  
Ontology : EGO-EBIprotein binding  nucleus  nucleoplasm  trans-Golgi network  centriole  cytosol  beta-catenin binding  beta-catenin binding  protein localization  nuclear speck  negative regulation of Wnt signaling pathway  identical protein binding  protein homodimerization activity  fat cell differentiation  negative regulation of transcription, DNA-templated  protein homotetramerization  cardiac muscle cell differentiation  
NDEx NetworkCBY1
Atlas of Cancer Signalling NetworkCBY1
Wikipedia pathwaysCBY1
Orthology - Evolution
OrthoDB25776
GeneTree (enSembl)ENSG00000100211
Phylogenetic Trees/Animal Genes : TreeFamCBY1
HOVERGENQ9Y3M2
HOGENOMQ9Y3M2
Homologs : HomoloGeneCBY1
Homology/Alignments : Family Browser (UCSC)CBY1
Gene fusions - Rearrangements
Fusion : MitelmanEMID1/CBY1 [22q12.2/22q13.1]  [t(22;22)(q12;q13)]  
Fusion: TCGAEMID1 22q12.2 CBY1 22q13.1 OV
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCBY1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CBY1
dbVarCBY1
ClinVarCBY1
1000_GenomesCBY1 
Exome Variant ServerCBY1
ExAC (Exome Aggregation Consortium)CBY1 (select the gene name)
Genetic variants : HAPMAP25776
Genomic Variants (DGV)CBY1 [DGVbeta]
DECIPHERCBY1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCBY1 
Mutations
ICGC Data PortalCBY1 
TCGA Data PortalCBY1 
Broad Tumor PortalCBY1
OASIS PortalCBY1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCBY1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCBY1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CBY1
DgiDB (Drug Gene Interaction Database)CBY1
DoCM (Curated mutations)CBY1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CBY1 (select a term)
intoGenCBY1
Cancer3DCBY1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607757   
Orphanet
MedgenCBY1
Genetic Testing Registry CBY1
NextProtQ9Y3M2 [Medical]
TSGene25776
GENETestsCBY1
Huge Navigator CBY1 [HugePedia]
snp3D : Map Gene to Disease25776
BioCentury BCIQCBY1
ClinGenCBY1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD25776
Chemical/Pharm GKB GenePA25886
Clinical trialCBY1
Miscellaneous
canSAR (ICR)CBY1 (select the gene name)
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCBY1
EVEXCBY1
GoPubMedCBY1
iHOPCBY1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:09:04 CEST 2017

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