Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CCKAR (cholecystokinin A receptor)

Identity

Other aliasCCK-A
CCK1-R
CCK1R
CCKRA
HGNC (Hugo) CCKAR
LocusID (NCBI) 886
Atlas_Id 46064
Location 4p15.2  [Link to chromosome band 4p15]
Location_base_pair Starts at 26483018 and ends at 26492042 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CCKAR   1570
Cards
Entrez_Gene (NCBI)CCKAR  886  cholecystokinin A receptor
AliasesCCK-A; CCK1-R; CCK1R; CCKRA
GeneCards (Weizmann)CCKAR
Ensembl hg19 (Hinxton)ENSG00000163394 [Gene_View]  chr4:26483018-26492042 [Contig_View]  CCKAR [Vega]
Ensembl hg38 (Hinxton)ENSG00000163394 [Gene_View]  chr4:26483018-26492042 [Contig_View]  CCKAR [Vega]
ICGC DataPortalENSG00000163394
TCGA cBioPortalCCKAR
AceView (NCBI)CCKAR
Genatlas (Paris)CCKAR
WikiGenes886
SOURCE (Princeton)CCKAR
Genetics Home Reference (NIH)CCKAR
Genomic and cartography
GoldenPath hg19 (UCSC)CCKAR  -     chr4:26483018-26492042 -  4p15.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CCKAR  -     4p15.2   [Description]    (hg38-Dec_2013)
EnsemblCCKAR - 4p15.2 [CytoView hg19]  CCKAR - 4p15.2 [CytoView hg38]
Mapping of homologs : NCBICCKAR [Mapview hg19]  CCKAR [Mapview hg38]
OMIM118444   
Gene and transcription
Genbank (Entrez)AK313978 AY322549 BC074987 L13605 L19315
RefSeq transcript (Entrez)NM_000730
RefSeq genomic (Entrez)NC_000004 NC_018915 NG_012053 NT_006316 NW_004929315
Consensus coding sequences : CCDS (NCBI)CCKAR
Cluster EST : UnigeneHs.129 [ NCBI ]
CGAP (NCI)Hs.129
Alternative Splicing GalleryENSG00000163394
Gene ExpressionCCKAR [ NCBI-GEO ]   CCKAR [ EBI - ARRAY_EXPRESS ]   CCKAR [ SEEK ]   CCKAR [ MEM ]
Gene Expression Viewer (FireBrowse)CCKAR [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)886
GTEX Portal (Tissue expression)CCKAR
Protein : pattern, domain, 3D structure
UniProt/SwissProtP32238   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP32238  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP32238
Splice isoforms : SwissVarP32238
PhosPhoSitePlusP32238
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)Cholcskin_rcpt    Cholcy_rcpt_A    CholecystokininA_recpt_N    GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)    CholecysA-Rec_N (PF09193)   
Domain families : Pfam (NCBI)pfam00001    pfam09193   
Conserved Domain (NCBI)CCKAR
DMDM Disease mutations886
Blocks (Seattle)CCKAR
PDB (SRS)1D6G    1HZN    1PB2   
PDB (PDBSum)1D6G    1HZN    1PB2   
PDB (IMB)1D6G    1HZN    1PB2   
PDB (RSDB)1D6G    1HZN    1PB2   
Structural Biology KnowledgeBase1D6G    1HZN    1PB2   
SCOP (Structural Classification of Proteins)1D6G    1HZN    1PB2   
CATH (Classification of proteins structures)1D6G    1HZN    1PB2   
SuperfamilyP32238
Human Protein AtlasENSG00000163394
Peptide AtlasP32238
HPRD00322
IPIIPI00027666   
Protein Interaction databases
DIP (DOE-UCLA)P32238
IntAct (EBI)P32238
FunCoupENSG00000163394
BioGRIDCCKAR
STRING (EMBL)CCKAR
ZODIACCCKAR
Ontologies - Pathways
QuickGOP32238
Ontology : AmiGOtemperature homeostasis  gastric acid secretion  neuron migration  reduction of food intake in response to dietary excess  cholecystokinin receptor activity  lysosome  endosome  endoplasmic reticulum  cytosol  plasma membrane  integral component of plasma membrane  phospholipase C-activating G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  axonogenesis  response to nutrient  digestion  feeding behavior  response to radiation  response to heat  insulin secretion  pancreatic juice secretion  forebrain development  pancreas development  organ regeneration  actin cytoskeleton reorganization  response to lipopolysaccharide  cellular response to hormone stimulus  cholecystokinin signaling pathway  response to starvation  terminal bouton  regulation of potassium ion transport  regulation of hormone secretion  response to glucocorticoid  regulation of calcium ion transport  positive regulation of somatostatin secretion  
Ontology : EGO-EBItemperature homeostasis  gastric acid secretion  neuron migration  reduction of food intake in response to dietary excess  cholecystokinin receptor activity  lysosome  endosome  endoplasmic reticulum  cytosol  plasma membrane  integral component of plasma membrane  phospholipase C-activating G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  axonogenesis  response to nutrient  digestion  feeding behavior  response to radiation  response to heat  insulin secretion  pancreatic juice secretion  forebrain development  pancreas development  organ regeneration  actin cytoskeleton reorganization  response to lipopolysaccharide  cellular response to hormone stimulus  cholecystokinin signaling pathway  response to starvation  terminal bouton  regulation of potassium ion transport  regulation of hormone secretion  response to glucocorticoid  regulation of calcium ion transport  positive regulation of somatostatin secretion  
Pathways : KEGGCalcium signaling pathway    Neuroactive ligand-receptor interaction    Insulin secretion    Pancreatic secretion   
NDEx NetworkCCKAR
Atlas of Cancer Signalling NetworkCCKAR
Wikipedia pathwaysCCKAR
Orthology - Evolution
OrthoDB886
GeneTree (enSembl)ENSG00000163394
Phylogenetic Trees/Animal Genes : TreeFamCCKAR
HOVERGENP32238
HOGENOMP32238
Homologs : HomoloGeneCCKAR
Homology/Alignments : Family Browser (UCSC)CCKAR
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCCKAR [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CCKAR
dbVarCCKAR
ClinVarCCKAR
1000_GenomesCCKAR 
Exome Variant ServerCCKAR
ExAC (Exome Aggregation Consortium)CCKAR (select the gene name)
Genetic variants : HAPMAP886
Genomic Variants (DGV)CCKAR [DGVbeta]
DECIPHER (Syndromes)4:26483018-26492042  ENSG00000163394
CONAN: Copy Number AnalysisCCKAR 
Mutations
ICGC Data PortalCCKAR 
TCGA Data PortalCCKAR 
Broad Tumor PortalCCKAR
OASIS PortalCCKAR [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCCKAR  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCCKAR
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CCKAR
DgiDB (Drug Gene Interaction Database)CCKAR
DoCM (Curated mutations)CCKAR (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CCKAR (select a term)
intoGenCCKAR
Cancer3DCCKAR(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM118444   
Orphanet
MedgenCCKAR
Genetic Testing Registry CCKAR
NextProtP32238 [Medical]
TSGene886
GENETestsCCKAR
Huge Navigator CCKAR [HugePedia]
snp3D : Map Gene to Disease886
BioCentury BCIQCCKAR
ClinGenCCKAR
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD886
Chemical/Pharm GKB GenePA26142
Clinical trialCCKAR
Miscellaneous
canSAR (ICR)CCKAR (select the gene name)
Probes
Litterature
PubMed79 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCCKAR
EVEXCCKAR
GoPubMedCCKAR
iHOPCCKAR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:59:02 CET 2017

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