Atlas of Genetics and Cytogenetics in Oncology and Haematology

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CCKAR (cholecystokinin A receptor)

Identity

Other aliasCCK-A
CCK1-R
CCK1R
CCKRA
HGNC (Hugo) CCKAR
LocusID (NCBI) 886
Atlas_Id 46064
Location 4p15.2  [Link to chromosome band 4p15]
Location_base_pair Starts at 26481396 and ends at 26490420 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CCKAR   1570
Cards
Entrez_Gene (NCBI)CCKAR  886  cholecystokinin A receptor
AliasesCCK-A; CCK1-R; CCK1R; CCKRA
GeneCards (Weizmann)CCKAR
Ensembl hg19 (Hinxton)ENSG00000163394 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163394 [Gene_View]  ENSG00000163394 [Sequence]  chr4:26481396-26490420 [Contig_View]  CCKAR [Vega]
ICGC DataPortalENSG00000163394
TCGA cBioPortalCCKAR
AceView (NCBI)CCKAR
Genatlas (Paris)CCKAR
WikiGenes886
SOURCE (Princeton)CCKAR
Genetics Home Reference (NIH)CCKAR
Genomic and cartography
GoldenPath hg38 (UCSC)CCKAR  -     chr4:26481396-26490420 -  4p15.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CCKAR  -     4p15.2   [Description]    (hg19-Feb_2009)
EnsemblCCKAR - 4p15.2 [CytoView hg19]  CCKAR - 4p15.2 [CytoView hg38]
Mapping of homologs : NCBICCKAR [Mapview hg19]  CCKAR [Mapview hg38]
OMIM118444   
Gene and transcription
Genbank (Entrez)AK313978 AY322549 BC074987 L13605 L19315
RefSeq transcript (Entrez)NM_000730
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CCKAR
Cluster EST : UnigeneHs.129 [ NCBI ]
CGAP (NCI)Hs.129
Alternative Splicing GalleryENSG00000163394
Gene ExpressionCCKAR [ NCBI-GEO ]   CCKAR [ EBI - ARRAY_EXPRESS ]   CCKAR [ SEEK ]   CCKAR [ MEM ]
Gene Expression Viewer (FireBrowse)CCKAR [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)886
GTEX Portal (Tissue expression)CCKAR
Human Protein AtlasENSG00000163394-CCKAR [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP32238   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP32238  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP32238
Splice isoforms : SwissVarP32238
PhosPhoSitePlusP32238
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)Cholcskin_rcpt    Cholcy_rcpt_A    CholecystokininA_recpt_N    GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)    CholecysA-Rec_N (PF09193)   
Domain families : Pfam (NCBI)pfam00001    pfam09193   
Domain families : Smart (EMBL)7TM_GPCR_Srsx (SM01381)  
Conserved Domain (NCBI)CCKAR
DMDM Disease mutations886
Blocks (Seattle)CCKAR
PDB (SRS)1D6G    1HZN    1PB2   
PDB (PDBSum)1D6G    1HZN    1PB2   
PDB (IMB)1D6G    1HZN    1PB2   
PDB (RSDB)1D6G    1HZN    1PB2   
Structural Biology KnowledgeBase1D6G    1HZN    1PB2   
SCOP (Structural Classification of Proteins)1D6G    1HZN    1PB2   
CATH (Classification of proteins structures)1D6G    1HZN    1PB2   
SuperfamilyP32238
Human Protein Atlas [tissue]ENSG00000163394-CCKAR [tissue]
Peptide AtlasP32238
HPRD00322
IPIIPI00027666   
Protein Interaction databases
DIP (DOE-UCLA)P32238
IntAct (EBI)P32238
FunCoupENSG00000163394
BioGRIDCCKAR
STRING (EMBL)CCKAR
ZODIACCCKAR
Ontologies - Pathways
QuickGOP32238
Ontology : AmiGOneuron migration  cholecystokinin receptor activity  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway  phospholipase C-activating G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  axonogenesis  response to nutrient  digestion  feeding behavior  forebrain development  cellular response to hormone stimulus  cholecystokinin signaling pathway  peptide binding  regulation of hormone secretion  response to peptide  
Ontology : EGO-EBIneuron migration  cholecystokinin receptor activity  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway  phospholipase C-activating G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  axonogenesis  response to nutrient  digestion  feeding behavior  forebrain development  cellular response to hormone stimulus  cholecystokinin signaling pathway  peptide binding  regulation of hormone secretion  response to peptide  
Pathways : KEGGNeuroactive ligand-receptor interaction    Calcium signaling pathway   
NDEx NetworkCCKAR
Atlas of Cancer Signalling NetworkCCKAR
Wikipedia pathwaysCCKAR
Orthology - Evolution
OrthoDB886
GeneTree (enSembl)ENSG00000163394
Phylogenetic Trees/Animal Genes : TreeFamCCKAR
HOVERGENP32238
HOGENOMP32238
Homologs : HomoloGeneCCKAR
Homology/Alignments : Family Browser (UCSC)CCKAR
Gene fusions - Rearrangements
Fusion : QuiverCCKAR
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCCKAR [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CCKAR
dbVarCCKAR
ClinVarCCKAR
1000_GenomesCCKAR 
Exome Variant ServerCCKAR
ExAC (Exome Aggregation Consortium)ENSG00000163394
GNOMAD BrowserENSG00000163394
Genetic variants : HAPMAP886
Genomic Variants (DGV)CCKAR [DGVbeta]
DECIPHERCCKAR [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCCKAR 
Mutations
ICGC Data PortalCCKAR 
TCGA Data PortalCCKAR 
Broad Tumor PortalCCKAR
OASIS PortalCCKAR [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCCKAR  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCCKAR
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CCKAR
DgiDB (Drug Gene Interaction Database)CCKAR
DoCM (Curated mutations)CCKAR (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CCKAR (select a term)
intoGenCCKAR
Cancer3DCCKAR(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM118444   
Orphanet
DisGeNETCCKAR
MedgenCCKAR
Genetic Testing Registry CCKAR
NextProtP32238 [Medical]
TSGene886
GENETestsCCKAR
Target ValidationCCKAR
Huge Navigator CCKAR [HugePedia]
snp3D : Map Gene to Disease886
BioCentury BCIQCCKAR
ClinGenCCKAR
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD886
Chemical/Pharm GKB GenePA26142
Clinical trialCCKAR
Miscellaneous
canSAR (ICR)CCKAR (select the gene name)
Probes
Litterature
PubMed84 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCCKAR
EVEXCCKAR
GoPubMedCCKAR
iHOPCCKAR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jun 22 16:17:54 CEST 2018
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