Identity
HGNC
LOCATION
11p15.4
LOCUSID
ALIAS
CCK-B,CCK2R,GASR
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 887
MIM: 118445
HGNC: 1571
Ensembl: ENSG00000110148
Variants:
dbSNP: 887
ClinVar: 887
TCGA: ENSG00000110148
COSMIC: CCKBR
RNA/Proteins
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA128406954 | Weight gain | Disease | VariantAnnotation | associated | PD | 20732371 | |
| PA166123368 | schizoaffective disorder | Disease | VariantAnnotation | associated | PD | 20732371 | |
| PA447216 | Schizophrenia | Disease | VariantAnnotation | associated | PD | 20732371 | |
| PA449061 | clozapine | Chemical | VariantAnnotation | associated | PD | 20732371 | |
| PA450688 | olanzapine | Chemical | VariantAnnotation | associated | PD | 20732371 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34924075 | 2022 | Cholecystokinin B receptor gene polymorphism (rs2941026) is associated with anxious personality and suicidal thoughts in a longitudinal study. | 0 |
| 35430166 | 2022 | Unique membranous gastrin receptor expression of parietal cells and its distribution pattern in the gastric oxyntic mucosa and fundic gland polyps. | 0 |
| 34924075 | 2022 | Cholecystokinin B receptor gene polymorphism (rs2941026) is associated with anxious personality and suicidal thoughts in a longitudinal study. | 0 |
| 35430166 | 2022 | Unique membranous gastrin receptor expression of parietal cells and its distribution pattern in the gastric oxyntic mucosa and fundic gland polyps. | 0 |
| 28980157 | 2018 | Expression of the Cholecystokinin-B Receptor in Neoplastic Gastric Cells. | 16 |
| 30115027 | 2018 | Low serum gastrin associated with ER(+) breast cancer development via inactivation of CCKBR/ERK/P65 signaling. | 6 |
| 28980157 | 2018 | Expression of the Cholecystokinin-B Receptor in Neoplastic Gastric Cells. | 16 |
| 30115027 | 2018 | Low serum gastrin associated with ER(+) breast cancer development via inactivation of CCKBR/ERK/P65 signaling. | 6 |
| 28739697 | 2017 | Z-360 Suppresses Tumor Growth in MIA PaCa-2-bearing Mice via Inhibition of Gastrin-induced Anti-Apoptotic Effects. | 3 |
| 28739697 | 2017 | Z-360 Suppresses Tumor Growth in MIA PaCa-2-bearing Mice via Inhibition of Gastrin-induced Anti-Apoptotic Effects. | 3 |
| 26508021 | 2016 | Expression of cholecystokinin receptors in colon cancer and the clinical correlation in Taiwan. | 1 |
| 26646278 | 2016 | A Common CCK-B Receptor Intronic Variant in Pancreatic Adenocarcinoma in a Hungarian Cohort. | 0 |
| 26910279 | 2016 | Assessment of cholecystokinin 2 receptor (CCK2R) in neoplastic tissue. | 19 |
| 27072272 | 2016 | Heterogeneous expression of cholecystokinin and gastrin receptor in stomach and pancreatic cancer: An immunohistochemical study. | 4 |
| 27518872 | 2016 | MiR-148a Functions as a Tumor Suppressor by Targeting CCK-BR via Inactivating STAT3 and Akt in Human Gastric Cancer. | 31 |
Citation
Dessen P
CCKBR (cholecystokinin B receptor)
Atlas Genet Cytogenet Oncol Haematol. 2003-10-01
Online version: http://atlasgeneticsoncology.org/gene/938/cckbr
