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CCKBR (cholecystokinin B receptor)

Identity

Other aliasCCK-B
CCK2R
GASR
HGNC (Hugo) CCKBR
LocusID (NCBI) 887
Atlas_Id 938
Location 11p15.4  [Link to chromosome band 11p15]
Location_base_pair Starts at 6259674 and ends at 6272127 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CCKBR (11p15.4) / NGLY1 (3p24.2)NGLY1 (3p24.2) / CCKBR (11p15.4)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Small Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)CCKBR   1571
Cards
Entrez_Gene (NCBI)CCKBR  887  cholecystokinin B receptor
AliasesCCK-B; CCK2R; GASR
GeneCards (Weizmann)CCKBR
Ensembl hg19 (Hinxton)ENSG00000110148 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000110148 [Gene_View]  chr11:6259674-6272127 [Contig_View]  CCKBR [Vega]
ICGC DataPortalENSG00000110148
TCGA cBioPortalCCKBR
AceView (NCBI)CCKBR
Genatlas (Paris)CCKBR
WikiGenes887
SOURCE (Princeton)CCKBR
Genetics Home Reference (NIH)CCKBR
Genomic and cartography
GoldenPath hg38 (UCSC)CCKBR  -     chr11:6259674-6272127 +  11p15.4   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CCKBR  -     11p15.4   [Description]    (hg19-Feb_2009)
EnsemblCCKBR - 11p15.4 [CytoView hg19]  CCKBR - 11p15.4 [CytoView hg38]
Mapping of homologs : NCBICCKBR [Mapview hg19]  CCKBR [Mapview hg38]
OMIM118445   
Gene and transcription
Genbank (Entrez)AF239668 AF441129 AK226020 AK292064 AK314266
RefSeq transcript (Entrez)NM_001318029 NM_176875
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CCKBR
Cluster EST : UnigeneHs.203 [ NCBI ]
CGAP (NCI)Hs.203
Alternative Splicing GalleryENSG00000110148
Gene ExpressionCCKBR [ NCBI-GEO ]   CCKBR [ EBI - ARRAY_EXPRESS ]   CCKBR [ SEEK ]   CCKBR [ MEM ]
Gene Expression Viewer (FireBrowse)CCKBR [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)887
GTEX Portal (Tissue expression)CCKBR
Protein : pattern, domain, 3D structure
UniProt/SwissProtP32239   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP32239  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP32239
Splice isoforms : SwissVarP32239
PhosPhoSitePlusP32239
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)Cholcskin_rcpt    Gastrin_rcpt    GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)CCKBR
DMDM Disease mutations887
Blocks (Seattle)CCKBR
PDB (SRS)1L4T   
PDB (PDBSum)1L4T   
PDB (IMB)1L4T   
PDB (RSDB)1L4T   
Structural Biology KnowledgeBase1L4T   
SCOP (Structural Classification of Proteins)1L4T   
CATH (Classification of proteins structures)1L4T   
SuperfamilyP32239
Human Protein AtlasENSG00000110148
Peptide AtlasP32239
HPRD00323
IPIIPI00027667   IPI00893039   IPI00893152   IPI00930734   IPI00982430   IPI00978207   IPI00976354   
Protein Interaction databases
DIP (DOE-UCLA)P32239
IntAct (EBI)P32239
FunCoupENSG00000110148
BioGRIDCCKBR
STRING (EMBL)CCKBR
ZODIACCCKBR
Ontologies - Pathways
QuickGOP32239
Ontology : AmiGOgastric acid secretion  phosphatidylinositol phospholipase C activity  cholecystokinin receptor activity  protein binding  plasma membrane  integral component of plasma membrane  cell surface receptor signaling pathway  phospholipase C-activating G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  digestion  sensory perception  feeding behavior  cell proliferation  positive regulation of cell proliferation  gastrin receptor activity  type B gastrin/cholecystokinin receptor binding  cholecystokinin signaling pathway  regulation of phosphatidylinositol 3-kinase activity  1-phosphatidylinositol-3-kinase regulator activity  digestive tract development  gland development  
Ontology : EGO-EBIgastric acid secretion  phosphatidylinositol phospholipase C activity  cholecystokinin receptor activity  protein binding  plasma membrane  integral component of plasma membrane  cell surface receptor signaling pathway  phospholipase C-activating G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  digestion  sensory perception  feeding behavior  cell proliferation  positive regulation of cell proliferation  gastrin receptor activity  type B gastrin/cholecystokinin receptor binding  cholecystokinin signaling pathway  regulation of phosphatidylinositol 3-kinase activity  1-phosphatidylinositol-3-kinase regulator activity  digestive tract development  gland development  
Pathways : KEGGCalcium signaling pathway    Neuroactive ligand-receptor interaction    Gastric acid secretion   
NDEx NetworkCCKBR
Atlas of Cancer Signalling NetworkCCKBR
Wikipedia pathwaysCCKBR
Orthology - Evolution
OrthoDB887
GeneTree (enSembl)ENSG00000110148
Phylogenetic Trees/Animal Genes : TreeFamCCKBR
HOVERGENP32239
HOGENOMP32239
Homologs : HomoloGeneCCKBR
Homology/Alignments : Family Browser (UCSC)CCKBR
Gene fusions - Rearrangements
Fusion : MitelmanNGLY1/CCKBR [3p24.2/11p15.4]  [t(3;11)(p24;p15)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCCKBR [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CCKBR
dbVarCCKBR
ClinVarCCKBR
1000_GenomesCCKBR 
Exome Variant ServerCCKBR
ExAC (Exome Aggregation Consortium)CCKBR (select the gene name)
Genetic variants : HAPMAP887
Genomic Variants (DGV)CCKBR [DGVbeta]
DECIPHERCCKBR [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCCKBR 
Mutations
ICGC Data PortalCCKBR 
TCGA Data PortalCCKBR 
Broad Tumor PortalCCKBR
OASIS PortalCCKBR [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCCKBR  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCCKBR
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CCKBR
DgiDB (Drug Gene Interaction Database)CCKBR
DoCM (Curated mutations)CCKBR (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CCKBR (select a term)
intoGenCCKBR
Cancer3DCCKBR(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM118445   
Orphanet
MedgenCCKBR
Genetic Testing Registry CCKBR
NextProtP32239 [Medical]
TSGene887
GENETestsCCKBR
Target ValidationCCKBR
Huge Navigator CCKBR [HugePedia]
snp3D : Map Gene to Disease887
BioCentury BCIQCCKBR
ClinGenCCKBR
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD887
Chemical/Pharm GKB GenePA26143
Clinical trialCCKBR
Miscellaneous
canSAR (ICR)CCKBR (select the gene name)
Probes
Litterature
PubMed118 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCCKBR
EVEXCCKBR
GoPubMedCCKBR
iHOPCCKBR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:27:04 CEST 2017

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