Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CCL1 (C-C motif chemokine ligand 1)

Identity

Alias_namesSCYA1
small inducible cytokine A1 (I-309, homologous to mouse Tca-3)
chemokine (C-C motif) ligand 1
Alias_symbol (synonym)I-309
TCA3
P500
SISe
Other alias
HGNC (Hugo) CCL1
LocusID (NCBI) 6346
Atlas_Id 53596
Location 17q12  [Link to chromosome band 17q12]
Location_base_pair Starts at 32687347 and ends at 32690252 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CCL1   10609
Cards
Entrez_Gene (NCBI)CCL1  6346  C-C motif chemokine ligand 1
AliasesI-309; P500; SCYA1; SISe; 
TCA3
GeneCards (Weizmann)CCL1
Ensembl hg19 (Hinxton)ENSG00000108702 [Gene_View]  chr17:32687347-32690252 [Contig_View]  CCL1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000108702 [Gene_View]  chr17:32687347-32690252 [Contig_View]  CCL1 [Vega]
ICGC DataPortalENSG00000108702
TCGA cBioPortalCCL1
AceView (NCBI)CCL1
Genatlas (Paris)CCL1
WikiGenes6346
SOURCE (Princeton)CCL1
Genetics Home Reference (NIH)CCL1
Genomic and cartography
GoldenPath hg19 (UCSC)CCL1  -     chr17:32687347-32690252 -  17q12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CCL1  -     17q12   [Description]    (hg38-Dec_2013)
EnsemblCCL1 - 17q12 [CytoView hg19]  CCL1 - 17q12 [CytoView hg38]
Mapping of homologs : NCBICCL1 [Mapview hg19]  CCL1 [Mapview hg38]
OMIM182281   
Gene and transcription
Genbank (Entrez)AK312183 BC105073 BC105075 BC111914 DA620119
RefSeq transcript (Entrez)NM_002981
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010783 NW_004929407
Consensus coding sequences : CCDS (NCBI)CCL1
Cluster EST : UnigeneHs.72918 [ NCBI ]
CGAP (NCI)Hs.72918
Alternative Splicing GalleryENSG00000108702
Gene ExpressionCCL1 [ NCBI-GEO ]   CCL1 [ EBI - ARRAY_EXPRESS ]   CCL1 [ SEEK ]   CCL1 [ MEM ]
Gene Expression Viewer (FireBrowse)CCL1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6346
GTEX Portal (Tissue expression)CCL1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP22362   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP22362  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP22362
Splice isoforms : SwissVarP22362
PhosPhoSitePlusP22362
Domaine pattern : Prosite (Expaxy)SMALL_CYTOKINES_CC (PS00472)   
Domains : Interpro (EBI)Chemokine_CC_CS    Chemokine_IL8-like_dom   
Domain families : Pfam (Sanger)IL8 (PF00048)   
Domain families : Pfam (NCBI)pfam00048   
Domain families : Smart (EMBL)SCY (SM00199)  
Conserved Domain (NCBI)CCL1
DMDM Disease mutations6346
Blocks (Seattle)CCL1
PDB (SRS)1EL0    4OIJ    4OIK   
PDB (PDBSum)1EL0    4OIJ    4OIK   
PDB (IMB)1EL0    4OIJ    4OIK   
PDB (RSDB)1EL0    4OIJ    4OIK   
Structural Biology KnowledgeBase1EL0    4OIJ    4OIK   
SCOP (Structural Classification of Proteins)1EL0    4OIJ    4OIK   
CATH (Classification of proteins structures)1EL0    4OIJ    4OIK   
SuperfamilyP22362
Human Protein AtlasENSG00000108702
Peptide AtlasP22362
HPRD01654
IPIIPI00026221   
Protein Interaction databases
DIP (DOE-UCLA)P22362
IntAct (EBI)P22362
FunCoupENSG00000108702
BioGRIDCCL1
STRING (EMBL)CCL1
ZODIACCCL1
Ontologies - Pathways
QuickGOP22362
Ontology : AmiGOmonocyte chemotaxis  extracellular region  extracellular space  cell  cellular calcium ion homeostasis  chemotaxis  inflammatory response  signal transduction  G-protein coupled receptor signaling pathway  chemokine activity  viral process  neutrophil chemotaxis  positive regulation of GTPase activity  CCR chemokine receptor binding  lymphocyte chemotaxis  positive regulation of inflammatory response  response to glucocorticoid  chemokine-mediated signaling pathway  positive regulation of ERK1 and ERK2 cascade  cellular response to interferon-gamma  cellular response to interleukin-1  cellular response to tumor necrosis factor  
Ontology : EGO-EBImonocyte chemotaxis  extracellular region  extracellular space  cell  cellular calcium ion homeostasis  chemotaxis  inflammatory response  signal transduction  G-protein coupled receptor signaling pathway  chemokine activity  viral process  neutrophil chemotaxis  positive regulation of GTPase activity  CCR chemokine receptor binding  lymphocyte chemotaxis  positive regulation of inflammatory response  response to glucocorticoid  chemokine-mediated signaling pathway  positive regulation of ERK1 and ERK2 cascade  cellular response to interferon-gamma  cellular response to interleukin-1  cellular response to tumor necrosis factor  
Pathways : KEGGCytokine-cytokine receptor interaction    Chemokine signaling pathway   
NDEx NetworkCCL1
Atlas of Cancer Signalling NetworkCCL1
Wikipedia pathwaysCCL1
Orthology - Evolution
OrthoDB6346
GeneTree (enSembl)ENSG00000108702
Phylogenetic Trees/Animal Genes : TreeFamCCL1
HOVERGENP22362
HOGENOMP22362
Homologs : HomoloGeneCCL1
Homology/Alignments : Family Browser (UCSC)CCL1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCCL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CCL1
dbVarCCL1
ClinVarCCL1
1000_GenomesCCL1 
Exome Variant ServerCCL1
ExAC (Exome Aggregation Consortium)CCL1 (select the gene name)
Genetic variants : HAPMAP6346
Genomic Variants (DGV)CCL1 [DGVbeta]
DECIPHER (Syndromes)17:32687347-32690252  ENSG00000108702
CONAN: Copy Number AnalysisCCL1 
Mutations
ICGC Data PortalCCL1 
TCGA Data PortalCCL1 
Broad Tumor PortalCCL1
OASIS PortalCCL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCCL1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCCL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)TBsLVD Tuberculosis susceptibility Locus Variation Database
BioMutasearch CCL1
DgiDB (Drug Gene Interaction Database)CCL1
DoCM (Curated mutations)CCL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CCL1 (select a term)
intoGenCCL1
Cancer3DCCL1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM182281   
Orphanet
MedgenCCL1
Genetic Testing Registry CCL1
NextProtP22362 [Medical]
TSGene6346
GENETestsCCL1
Huge Navigator CCL1 [HugePedia]
snp3D : Map Gene to Disease6346
BioCentury BCIQCCL1
ClinGenCCL1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6346
Chemical/Pharm GKB GenePA35542
Clinical trialCCL1
Miscellaneous
canSAR (ICR)CCL1 (select the gene name)
Probes
Litterature
PubMed56 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCCL1
EVEXCCL1
GoPubMedCCL1
iHOPCCL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:59:03 CET 2017

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