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CCL13 (C-C motif chemokine ligand 13)

Identity

Alias_namesSCYA13
small inducible cytokine subfamily A (Cys-Cys), member 13
chemokine (C-C motif) ligand 13
Alias_symbol (synonym)MCP-4
NCC-1
SCYL1
CKb10
MGC17134
Other aliasNCC1
HGNC (Hugo) CCL13
LocusID (NCBI) 6357
Atlas_Id 55377
Location 17q12  [Link to chromosome band 17q12]
Location_base_pair Starts at 34356452 and ends at 34358610 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CCL13   10611
Cards
Entrez_Gene (NCBI)CCL13  6357  C-C motif chemokine ligand 13
AliasesCKb10; MCP-4; NCC-1; NCC1; 
SCYA13; SCYL1
GeneCards (Weizmann)CCL13
Ensembl hg19 (Hinxton)ENSG00000181374 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000181374 [Gene_View]  chr17:34356452-34358610 [Contig_View]  CCL13 [Vega]
ICGC DataPortalENSG00000181374
TCGA cBioPortalCCL13
AceView (NCBI)CCL13
Genatlas (Paris)CCL13
WikiGenes6357
SOURCE (Princeton)CCL13
Genetics Home Reference (NIH)CCL13
Genomic and cartography
GoldenPath hg38 (UCSC)CCL13  -     chr17:34356452-34358610 +  17q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CCL13  -     17q12   [Description]    (hg19-Feb_2009)
EnsemblCCL13 - 17q12 [CytoView hg19]  CCL13 - 17q12 [CytoView hg38]
Mapping of homologs : NCBICCL13 [Mapview hg19]  CCL13 [Mapview hg38]
OMIM601391   
Gene and transcription
Genbank (Entrez)AJ001634 BC008621 BT007385 CR450337 DQ891497
RefSeq transcript (Entrez)NM_005408
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CCL13
Cluster EST : UnigeneHs.414629 [ NCBI ]
CGAP (NCI)Hs.414629
Alternative Splicing GalleryENSG00000181374
Gene ExpressionCCL13 [ NCBI-GEO ]   CCL13 [ EBI - ARRAY_EXPRESS ]   CCL13 [ SEEK ]   CCL13 [ MEM ]
Gene Expression Viewer (FireBrowse)CCL13 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6357
GTEX Portal (Tissue expression)CCL13
Human Protein AtlasENSG00000181374-CCL13 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99616   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99616  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99616
Splice isoforms : SwissVarQ99616
PhosPhoSitePlusQ99616
Domaine pattern : Prosite (Expaxy)SMALL_CYTOKINES_CC (PS00472)   
Domains : Interpro (EBI)Chemokine_CC_CS    Chemokine_IL8-like_dom   
Domain families : Pfam (Sanger)IL8 (PF00048)   
Domain families : Pfam (NCBI)pfam00048   
Domain families : Smart (EMBL)SCY (SM00199)  
Conserved Domain (NCBI)CCL13
DMDM Disease mutations6357
Blocks (Seattle)CCL13
PDB (SRS)2RA4   
PDB (PDBSum)2RA4   
PDB (IMB)2RA4   
PDB (RSDB)2RA4   
Structural Biology KnowledgeBase2RA4   
SCOP (Structural Classification of Proteins)2RA4   
CATH (Classification of proteins structures)2RA4   
SuperfamilyQ99616
Human Protein Atlas [tissue]ENSG00000181374-CCL13 [tissue]
Peptide AtlasQ99616
HPRD03230
IPIIPI00016914   
Protein Interaction databases
DIP (DOE-UCLA)Q99616
IntAct (EBI)Q99616
FunCoupENSG00000181374
BioGRIDCCL13
STRING (EMBL)CCL13
ZODIACCCL13
Ontologies - Pathways
QuickGOQ99616
Ontology : AmiGOmonocyte chemotaxis  receptor binding  extracellular region  extracellular space  cell  cellular calcium ion homeostasis  chemotaxis  inflammatory response  cytoskeleton organization  signal transduction  G-protein coupled receptor signaling pathway  cell-cell signaling  chemokine activity  regulation of cell shape  neutrophil chemotaxis  positive regulation of GTPase activity  CCR chemokine receptor binding  eosinophil chemotaxis  lymphocyte chemotaxis  chemokine-mediated signaling pathway  positive regulation of ERK1 and ERK2 cascade  cellular response to interferon-gamma  cellular response to interleukin-1  cellular response to tumor necrosis factor  
Ontology : EGO-EBImonocyte chemotaxis  receptor binding  extracellular region  extracellular space  cell  cellular calcium ion homeostasis  chemotaxis  inflammatory response  cytoskeleton organization  signal transduction  G-protein coupled receptor signaling pathway  cell-cell signaling  chemokine activity  regulation of cell shape  neutrophil chemotaxis  positive regulation of GTPase activity  CCR chemokine receptor binding  eosinophil chemotaxis  lymphocyte chemotaxis  chemokine-mediated signaling pathway  positive regulation of ERK1 and ERK2 cascade  cellular response to interferon-gamma  cellular response to interleukin-1  cellular response to tumor necrosis factor  
Pathways : KEGGCytokine-cytokine receptor interaction    Chemokine signaling pathway    NF-kappa B signaling pathway   
NDEx NetworkCCL13
Atlas of Cancer Signalling NetworkCCL13
Wikipedia pathwaysCCL13
Orthology - Evolution
OrthoDB6357
GeneTree (enSembl)ENSG00000181374
Phylogenetic Trees/Animal Genes : TreeFamCCL13
HOVERGENQ99616
HOGENOMQ99616
Homologs : HomoloGeneCCL13
Homology/Alignments : Family Browser (UCSC)CCL13
Gene fusions - Rearrangements
Tumor Fusion PortalCCL13
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCCL13 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CCL13
dbVarCCL13
ClinVarCCL13
1000_GenomesCCL13 
Exome Variant ServerCCL13
ExAC (Exome Aggregation Consortium)ENSG00000181374
GNOMAD BrowserENSG00000181374
Genetic variants : HAPMAP6357
Genomic Variants (DGV)CCL13 [DGVbeta]
DECIPHERCCL13 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCCL13 
Mutations
ICGC Data PortalCCL13 
TCGA Data PortalCCL13 
Broad Tumor PortalCCL13
OASIS PortalCCL13 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCCL13  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCCL13
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CCL13
DgiDB (Drug Gene Interaction Database)CCL13
DoCM (Curated mutations)CCL13 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CCL13 (select a term)
intoGenCCL13
Cancer3DCCL13(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601391   
Orphanet
DisGeNETCCL13
MedgenCCL13
Genetic Testing Registry CCL13
NextProtQ99616 [Medical]
TSGene6357
GENETestsCCL13
Target ValidationCCL13
Huge Navigator CCL13 [HugePedia]
snp3D : Map Gene to Disease6357
BioCentury BCIQCCL13
ClinGenCCL13
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6357
Chemical/Pharm GKB GenePA35544
Clinical trialCCL13
Miscellaneous
canSAR (ICR)CCL13 (select the gene name)
Probes
Litterature
PubMed54 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCCL13
EVEXCCL13
GoPubMedCCL13
iHOPCCL13
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:06:22 CET 2017

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