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CCL14 (C-C motif chemokine ligand 14)

Identity

Alias_namesSCYA14
small inducible cytokine subfamily A (Cys-Cys), member 14
chemokine (C-C motif) ligand 14
Alias_symbol (synonym)HCC-1
HCC-3
NCC-2
SCYL2
CKb1
MCIF
Other aliasCC-1
CC-3
CKB1
HCC-1(1-74)
HCC-1/HCC-3
NCC2
SY14
HGNC (Hugo) CCL14
LocusID (NCBI) 6358
Atlas_Id 940
Location 17q12  [Link to chromosome band 17q12]
Location_base_pair Starts at 35983656 and ends at 35986728 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CCL14   10612
Cards
Entrez_Gene (NCBI)CCL14  6358  C-C motif chemokine ligand 14
AliasesCC-1; CC-3; CKB1; HCC-1; 
HCC-1(1-74); HCC-1/HCC-3; HCC-3; MCIF; NCC-2; NCC2; SCYA14; SCYL2; SY14
GeneCards (Weizmann)CCL14
Ensembl hg19 (Hinxton)ENSG00000276409 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000276409 [Gene_View]  chr17:35983656-35986728 [Contig_View]  CCL14 [Vega]
ICGC DataPortalENSG00000276409
TCGA cBioPortalCCL14
AceView (NCBI)CCL14
Genatlas (Paris)CCL14
WikiGenes6358
SOURCE (Princeton)CCL14
Genetics Home Reference (NIH)CCL14
Genomic and cartography
GoldenPath hg38 (UCSC)CCL14  -     chr17:35983656-35986728 -  17q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CCL14  -     17q12   [Description]    (hg19-Feb_2009)
EnsemblCCL14 - 17q12 [CytoView hg19]  CCL14 - 17q12 [CytoView hg38]
Mapping of homologs : NCBICCL14 [Mapview hg19]  CCL14 [Mapview hg38]
OMIM601392   
Gene and transcription
Genbank (Entrez)AA612866 AK122606 BC038289 BC045165 BC050647
RefSeq transcript (Entrez)NM_004166 NM_032962 NM_032963
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_187614
Consensus coding sequences : CCDS (NCBI)CCL14
Cluster EST : UnigeneHs.740501 [ NCBI ]
CGAP (NCI)Hs.740501
Alternative Splicing GalleryENSG00000276409
Gene ExpressionCCL14 [ NCBI-GEO ]   CCL14 [ EBI - ARRAY_EXPRESS ]   CCL14 [ SEEK ]   CCL14 [ MEM ]
Gene Expression Viewer (FireBrowse)CCL14 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6358
GTEX Portal (Tissue expression)CCL14
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ16627   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ16627  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ16627
Splice isoforms : SwissVarQ16627
PhosPhoSitePlusQ16627
Domaine pattern : Prosite (Expaxy)SMALL_CYTOKINES_CC (PS00472)   
Domains : Interpro (EBI)Chemokine_CC_CS    Chemokine_IL8-like_dom   
Domain families : Pfam (Sanger)IL8 (PF00048)   
Domain families : Pfam (NCBI)pfam00048   
Domain families : Smart (EMBL)SCY (SM00199)  
Conserved Domain (NCBI)CCL14
DMDM Disease mutations6358
Blocks (Seattle)CCL14
PDB (SRS)2Q8R    2Q8T   
PDB (PDBSum)2Q8R    2Q8T   
PDB (IMB)2Q8R    2Q8T   
PDB (RSDB)2Q8R    2Q8T   
Structural Biology KnowledgeBase2Q8R    2Q8T   
SCOP (Structural Classification of Proteins)2Q8R    2Q8T   
CATH (Classification of proteins structures)2Q8R    2Q8T   
SuperfamilyQ16627
Human Protein AtlasENSG00000276409
Peptide AtlasQ16627
HPRD03231
IPIIPI00003375   IPI00215742   
Protein Interaction databases
DIP (DOE-UCLA)Q16627
IntAct (EBI)Q16627
FunCoupENSG00000276409
BioGRIDCCL14
STRING (EMBL)CCL14
ZODIACCCL14
Ontologies - Pathways
QuickGOQ16627
Ontology : AmiGOmonocyte chemotaxis  extracellular space  cell  cellular calcium ion homeostasis  inflammatory response  G-protein coupled receptor signaling pathway  chemokine activity  positive regulation of cell proliferation  neutrophil chemotaxis  positive regulation of GTPase activity  CCR chemokine receptor binding  lymphocyte chemotaxis  chemokine-mediated signaling pathway  positive regulation of ERK1 and ERK2 cascade  cellular response to interferon-gamma  cellular response to interleukin-1  cellular response to tumor necrosis factor  
Ontology : EGO-EBImonocyte chemotaxis  extracellular space  cell  cellular calcium ion homeostasis  inflammatory response  G-protein coupled receptor signaling pathway  chemokine activity  positive regulation of cell proliferation  neutrophil chemotaxis  positive regulation of GTPase activity  CCR chemokine receptor binding  lymphocyte chemotaxis  chemokine-mediated signaling pathway  positive regulation of ERK1 and ERK2 cascade  cellular response to interferon-gamma  cellular response to interleukin-1  cellular response to tumor necrosis factor  
Pathways : KEGGCytokine-cytokine receptor interaction    Chemokine signaling pathway   
NDEx NetworkCCL14
Atlas of Cancer Signalling NetworkCCL14
Wikipedia pathwaysCCL14
Orthology - Evolution
OrthoDB6358
GeneTree (enSembl)ENSG00000276409
Phylogenetic Trees/Animal Genes : TreeFamCCL14
HOVERGENQ16627
HOGENOMQ16627
Homologs : HomoloGeneCCL14
Homology/Alignments : Family Browser (UCSC)CCL14
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCCL14 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CCL14
dbVarCCL14
ClinVarCCL14
1000_GenomesCCL14 
Exome Variant ServerCCL14
ExAC (Exome Aggregation Consortium)CCL14 (select the gene name)
Genetic variants : HAPMAP6358
Genomic Variants (DGV)CCL14 [DGVbeta]
DECIPHERCCL14 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCCL14 
Mutations
ICGC Data PortalCCL14 
TCGA Data PortalCCL14 
Broad Tumor PortalCCL14
OASIS PortalCCL14 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDCCL14
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CCL14
DgiDB (Drug Gene Interaction Database)CCL14
DoCM (Curated mutations)CCL14 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CCL14 (select a term)
intoGenCCL14
Cancer3DCCL14(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601392   
Orphanet
MedgenCCL14
Genetic Testing Registry CCL14
NextProtQ16627 [Medical]
TSGene6358
GENETestsCCL14
Target ValidationCCL14
Huge Navigator CCL14 [HugePedia]
snp3D : Map Gene to Disease6358
BioCentury BCIQCCL14
ClinGenCCL14
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6358
Chemical/Pharm GKB GenePA35545
Clinical trialCCL14
Miscellaneous
canSAR (ICR)CCL14 (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCCL14
EVEXCCL14
GoPubMedCCL14
iHOPCCL14
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:27:05 CEST 2017

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