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CCL15 (C-C motif chemokine ligand 15)

Identity

Alias_namesSCYA15
small inducible cytokine subfamily A (Cys-Cys), member 15
chemokine (C-C motif) ligand 15
Alias_symbol (synonym)HCC-2
NCC-3
SCYL3
MIP-5
Lkn-1
MIP-1d
HMRP-2B
HGNC (Hugo) CCL15
LocusID (NCBI) 6359
Atlas_Id 941
Location 17q12  [Link to chromosome band 17q12]
Location_base_pair Starts at 34324618 and ends at 34329084 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CCL15   10613
Cards
Entrez_Gene (NCBI)CCL15  6359  C-C motif chemokine ligand 15
AliasesHCC-2; HMRP-2B; LKN-1; LKN1; 
MIP-1; MIP-1D; MIP-5; MRP-2B; NCC-3; NCC3; SCYA15; SCYL3; SY15
GeneCards (Weizmann)CCL15
Ensembl hg19 (Hinxton)ENSG00000275688 [Gene_View]  chr17:34324618-34329084 [Contig_View]  CCL15 [Vega]
Ensembl hg38 (Hinxton)ENSG00000275688 [Gene_View]  chr17:34324618-34329084 [Contig_View]  CCL15 [Vega]
ICGC DataPortalENSG00000275688
TCGA cBioPortalCCL15
AceView (NCBI)CCL15
Genatlas (Paris)CCL15
WikiGenes6359
SOURCE (Princeton)CCL15
Genetics Home Reference (NIH)CCL15
Genomic and cartography
GoldenPath hg19 (UCSC)CCL15  -     chr17:34324618-34329084 -  17q12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CCL15  -     17q12   [Description]    (hg38-Dec_2013)
EnsemblCCL15 - 17q12 [CytoView hg19]  CCL15 - 17q12 [CytoView hg38]
Mapping of homologs : NCBICCL15 [Mapview hg19]  CCL15 [Mapview hg38]
OMIM601393   
Gene and transcription
Genbank (Entrez)AF031587 AI244164 BX098368 BX497188 U58914
RefSeq transcript (Entrez)NM_004167 NM_032964 NM_032965
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010783 NT_187614 NW_004929407
Consensus coding sequences : CCDS (NCBI)CCL15
Cluster EST : UnigeneHs.272493 [ NCBI ]
CGAP (NCI)Hs.272493
Alternative Splicing GalleryENSG00000275688
Gene ExpressionCCL15 [ NCBI-GEO ]   CCL15 [ EBI - ARRAY_EXPRESS ]   CCL15 [ SEEK ]   CCL15 [ MEM ]
Gene Expression Viewer (FireBrowse)CCL15 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6359
GTEX Portal (Tissue expression)CCL15
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ16663   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ16663  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ16663
Splice isoforms : SwissVarQ16663
PhosPhoSitePlusQ16663
Domaine pattern : Prosite (Expaxy)SMALL_CYTOKINES_CC (PS00472)   
Domains : Interpro (EBI)CCL15    Chemokine_CC_CS    Chemokine_IL8-like_dom   
Domain families : Pfam (Sanger)IL8 (PF00048)   
Domain families : Pfam (NCBI)pfam00048   
Domain families : Smart (EMBL)SCY (SM00199)  
Conserved Domain (NCBI)CCL15
DMDM Disease mutations6359
Blocks (Seattle)CCL15
PDB (SRS)2HCC   
PDB (PDBSum)2HCC   
PDB (IMB)2HCC   
PDB (RSDB)2HCC   
Structural Biology KnowledgeBase2HCC   
SCOP (Structural Classification of Proteins)2HCC   
CATH (Classification of proteins structures)2HCC   
SuperfamilyQ16663
Human Protein AtlasENSG00000275688
Peptide AtlasQ16663
HPRD03232
IPIIPI00003440   IPI00791995   
Protein Interaction databases
DIP (DOE-UCLA)Q16663
IntAct (EBI)Q16663
FunCoupENSG00000275688
BioGRIDCCL15
STRING (EMBL)CCL15
ZODIACCCL15
Ontologies - Pathways
QuickGOQ16663
Ontology : AmiGOmonocyte chemotaxis  receptor binding  extracellular space  cell  cellular calcium ion homeostasis  chemotaxis  inflammatory response  signal transduction  G-protein coupled receptor signaling pathway  cell-cell signaling  chemokine activity  heparin binding  neutrophil chemotaxis  chemoattractant activity  positive regulation of GTPase activity  CCR chemokine receptor binding  lymphocyte chemotaxis  positive regulation of inflammatory response  positive chemotaxis  chemokine-mediated signaling pathway  positive regulation of ERK1 and ERK2 cascade  cellular response to interferon-gamma  cellular response to interleukin-1  cellular response to tumor necrosis factor  
Ontology : EGO-EBImonocyte chemotaxis  receptor binding  extracellular space  cell  cellular calcium ion homeostasis  chemotaxis  inflammatory response  signal transduction  G-protein coupled receptor signaling pathway  cell-cell signaling  chemokine activity  heparin binding  neutrophil chemotaxis  chemoattractant activity  positive regulation of GTPase activity  CCR chemokine receptor binding  lymphocyte chemotaxis  positive regulation of inflammatory response  positive chemotaxis  chemokine-mediated signaling pathway  positive regulation of ERK1 and ERK2 cascade  cellular response to interferon-gamma  cellular response to interleukin-1  cellular response to tumor necrosis factor  
Pathways : KEGGCytokine-cytokine receptor interaction    Chemokine signaling pathway   
NDEx NetworkCCL15
Atlas of Cancer Signalling NetworkCCL15
Wikipedia pathwaysCCL15
Orthology - Evolution
OrthoDB6359
GeneTree (enSembl)ENSG00000275688
Phylogenetic Trees/Animal Genes : TreeFamCCL15
HOVERGENQ16663
HOGENOMQ16663
Homologs : HomoloGeneCCL15
Homology/Alignments : Family Browser (UCSC)CCL15
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCCL15 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CCL15
dbVarCCL15
ClinVarCCL15
1000_GenomesCCL15 
Exome Variant ServerCCL15
ExAC (Exome Aggregation Consortium)CCL15 (select the gene name)
Genetic variants : HAPMAP6359
Genomic Variants (DGV)CCL15 [DGVbeta]
DECIPHER (Syndromes)17:34324618-34329084  ENSG00000275688
CONAN: Copy Number AnalysisCCL15 
Mutations
ICGC Data PortalCCL15 
TCGA Data PortalCCL15 
Broad Tumor PortalCCL15
OASIS PortalCCL15 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCCL15  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCCL15
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CCL15
DgiDB (Drug Gene Interaction Database)CCL15
DoCM (Curated mutations)CCL15 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CCL15 (select a term)
intoGenCCL15
Cancer3DCCL15(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601393   
Orphanet
MedgenCCL15
Genetic Testing Registry CCL15
NextProtQ16663 [Medical]
TSGene6359
GENETestsCCL15
Huge Navigator CCL15 [HugePedia]
snp3D : Map Gene to Disease6359
BioCentury BCIQCCL15
ClinGenCCL15
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6359
Chemical/Pharm GKB GenePA35546
Clinical trialCCL15
Miscellaneous
canSAR (ICR)CCL15 (select the gene name)
Probes
Litterature
PubMed48 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCCL15
EVEXCCL15
GoPubMedCCL15
iHOPCCL15
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Nov 18 19:33:08 CET 2016

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