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CCL16 (C-C motif chemokine ligand 16)

Identity

Alias_namesSCYA16
small inducible cytokine subfamily A (Cys-Cys), member 16
chemokine (C-C motif) ligand 16
Alias_symbol (synonym)NCC-4
SCYL4
LEC
HCC-4
LMC
LCC-1
CKb12
Mtn-1
Other aliasILINCK
NCC4
HGNC (Hugo) CCL16
LocusID (NCBI) 6360
Atlas_Id 46181
Location 17q12  [Link to chromosome band 17q12]
Location_base_pair Starts at 35976493 and ends at 35981496 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ETV4 (17q21.31) / CCL16 (17q12)ETV4 17q21.31 / CCL16 17q12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CCL16   10614
Cards
Entrez_Gene (NCBI)CCL16  6360  C-C motif chemokine ligand 16
AliasesCKb12; HCC-4; ILINCK; LCC-1; 
LEC; LMC; Mtn-1; NCC-4; NCC4; SCYA16; SCYL4
GeneCards (Weizmann)CCL16
Ensembl hg19 (Hinxton)ENSG00000275152 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000275152 [Gene_View]  chr17:35976493-35981496 [Contig_View]  CCL16 [Vega]
ICGC DataPortalENSG00000275152
TCGA cBioPortalCCL16
AceView (NCBI)CCL16
Genatlas (Paris)CCL16
WikiGenes6360
SOURCE (Princeton)CCL16
Genetics Home Reference (NIH)CCL16
Genomic and cartography
GoldenPath hg38 (UCSC)CCL16  -     chr17:35976493-35981496 -  17q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CCL16  -     17q12   [Description]    (hg19-Feb_2009)
EnsemblCCL16 - 17q12 [CytoView hg19]  CCL16 - 17q12 [CytoView hg38]
Mapping of homologs : NCBICCL16 [Mapview hg19]  CCL16 [Mapview hg38]
OMIM601394   
Gene and transcription
Genbank (Entrez)AB007454 AF039955 AF055467 BC096352 BC099662
RefSeq transcript (Entrez)NM_004590
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_187614
Consensus coding sequences : CCDS (NCBI)CCL16
Cluster EST : UnigeneHs.10458 [ NCBI ]
CGAP (NCI)Hs.10458
Alternative Splicing GalleryENSG00000275152
Gene ExpressionCCL16 [ NCBI-GEO ]   CCL16 [ EBI - ARRAY_EXPRESS ]   CCL16 [ SEEK ]   CCL16 [ MEM ]
Gene Expression Viewer (FireBrowse)CCL16 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6360
GTEX Portal (Tissue expression)CCL16
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15467   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO15467  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO15467
Splice isoforms : SwissVarO15467
PhosPhoSitePlusO15467
Domaine pattern : Prosite (Expaxy)SMALL_CYTOKINES_CC (PS00472)   
Domains : Interpro (EBI)Chemokine_CC_CS    Chemokine_IL8-like_dom   
Domain families : Pfam (Sanger)IL8 (PF00048)   
Domain families : Pfam (NCBI)pfam00048   
Domain families : Smart (EMBL)SCY (SM00199)  
Conserved Domain (NCBI)CCL16
DMDM Disease mutations6360
Blocks (Seattle)CCL16
SuperfamilyO15467
Human Protein AtlasENSG00000275152
Peptide AtlasO15467
HPRD03233
IPIIPI00006717   IPI00978256   
Protein Interaction databases
DIP (DOE-UCLA)O15467
IntAct (EBI)O15467
FunCoupENSG00000275152
BioGRIDCCL16
STRING (EMBL)CCL16
ZODIACCCL16
Ontologies - Pathways
QuickGOO15467
Ontology : AmiGOmonocyte chemotaxis  extracellular region  extracellular space  chemotaxis  inflammatory response  cell communication  G-protein coupled receptor signaling pathway  cell-cell signaling  chemokine activity  neutrophil chemotaxis  chemoattractant activity  positive regulation of GTPase activity  CCR chemokine receptor binding  lymphocyte chemotaxis  positive chemotaxis  chemokine-mediated signaling pathway  positive regulation of ERK1 and ERK2 cascade  cellular response to interferon-gamma  cellular response to interleukin-1  cellular response to tumor necrosis factor  
Ontology : EGO-EBImonocyte chemotaxis  extracellular region  extracellular space  chemotaxis  inflammatory response  cell communication  G-protein coupled receptor signaling pathway  cell-cell signaling  chemokine activity  neutrophil chemotaxis  chemoattractant activity  positive regulation of GTPase activity  CCR chemokine receptor binding  lymphocyte chemotaxis  positive chemotaxis  chemokine-mediated signaling pathway  positive regulation of ERK1 and ERK2 cascade  cellular response to interferon-gamma  cellular response to interleukin-1  cellular response to tumor necrosis factor  
Pathways : KEGGCytokine-cytokine receptor interaction    Chemokine signaling pathway   
NDEx NetworkCCL16
Atlas of Cancer Signalling NetworkCCL16
Wikipedia pathwaysCCL16
Orthology - Evolution
OrthoDB6360
GeneTree (enSembl)ENSG00000275152
Phylogenetic Trees/Animal Genes : TreeFamCCL16
HOVERGENO15467
HOGENOMO15467
Homologs : HomoloGeneCCL16
Homology/Alignments : Family Browser (UCSC)CCL16
Gene fusions - Rearrangements
Fusion : MitelmanETV4/CCL16 [17q21.31/17q12]  [t(17;17)(q12;q21)]  
Fusion: TCGAETV4 17q21.31 CCL16 17q12 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCCL16 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CCL16
dbVarCCL16
ClinVarCCL16
1000_GenomesCCL16 
Exome Variant ServerCCL16
ExAC (Exome Aggregation Consortium)CCL16 (select the gene name)
Genetic variants : HAPMAP6360
Genomic Variants (DGV)CCL16 [DGVbeta]
DECIPHERCCL16 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCCL16 
Mutations
ICGC Data PortalCCL16 
TCGA Data PortalCCL16 
Broad Tumor PortalCCL16
OASIS PortalCCL16 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCCL16  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCCL16
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CCL16
DgiDB (Drug Gene Interaction Database)CCL16
DoCM (Curated mutations)CCL16 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CCL16 (select a term)
intoGenCCL16
Cancer3DCCL16(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601394   
Orphanet
MedgenCCL16
Genetic Testing Registry CCL16
NextProtO15467 [Medical]
TSGene6360
GENETestsCCL16
Huge Navigator CCL16 [HugePedia]
snp3D : Map Gene to Disease6360
BioCentury BCIQCCL16
ClinGenCCL16
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6360
Chemical/Pharm GKB GenePA35547
Clinical trialCCL16
Miscellaneous
canSAR (ICR)CCL16 (select the gene name)
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCCL16
EVEXCCL16
GoPubMedCCL16
iHOPCCL16
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:09:16 CEST 2017

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