Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CCL19 (C-C motif chemokine ligand 19)

Identity

Alias_namesSCYA19
small inducible cytokine subfamily A (Cys-Cys), member 19
chemokine (C-C motif) ligand 19
Alias_symbol (synonym)ELC
MIP-3b
exodus-3
CKb11
Other aliasMIP3B
HGNC (Hugo) CCL19
LocusID (NCBI) 6363
Atlas_Id 43862
Location 9p13.3  [Link to chromosome band 9p13]
Location_base_pair Starts at 34689567 and ends at 34691274 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CCL19   10617
Cards
Entrez_Gene (NCBI)CCL19  6363  C-C motif chemokine ligand 19
AliasesCKb11; ELC; MIP-3b; MIP3B; 
SCYA19
GeneCards (Weizmann)CCL19
Ensembl hg19 (Hinxton)ENSG00000172724 [Gene_View]  chr9:34689567-34691274 [Contig_View]  CCL19 [Vega]
Ensembl hg38 (Hinxton)ENSG00000172724 [Gene_View]  chr9:34689567-34691274 [Contig_View]  CCL19 [Vega]
ICGC DataPortalENSG00000172724
TCGA cBioPortalCCL19
AceView (NCBI)CCL19
Genatlas (Paris)CCL19
WikiGenes6363
SOURCE (Princeton)CCL19
Genetics Home Reference (NIH)CCL19
Genomic and cartography
GoldenPath hg19 (UCSC)CCL19  -     chr9:34689567-34691274 -  9p13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CCL19  -     9p13.3   [Description]    (hg38-Dec_2013)
EnsemblCCL19 - 9p13.3 [CytoView hg19]  CCL19 - 9p13.3 [CytoView hg38]
Mapping of homologs : NCBICCL19 [Mapview hg19]  CCL19 [Mapview hg38]
OMIM602227   
Gene and transcription
Genbank (Entrez)AB000887 AK311945 AX772806 BC027968 CR456868
RefSeq transcript (Entrez)NM_006274
RefSeq genomic (Entrez)NC_000009 NC_018920 NT_008413 NW_004929342
Consensus coding sequences : CCDS (NCBI)CCL19
Cluster EST : UnigeneHs.50002 [ NCBI ]
CGAP (NCI)Hs.50002
Alternative Splicing GalleryENSG00000172724
Gene ExpressionCCL19 [ NCBI-GEO ]   CCL19 [ EBI - ARRAY_EXPRESS ]   CCL19 [ SEEK ]   CCL19 [ MEM ]
Gene Expression Viewer (FireBrowse)CCL19 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6363
GTEX Portal (Tissue expression)CCL19
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99731   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99731  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99731
Splice isoforms : SwissVarQ99731
PhosPhoSitePlusQ99731
Domaine pattern : Prosite (Expaxy)SMALL_CYTOKINES_CC (PS00472)   
Domains : Interpro (EBI)Chemokine_CC_CS    Chemokine_IL8-like_dom   
Domain families : Pfam (Sanger)IL8 (PF00048)   
Domain families : Pfam (NCBI)pfam00048   
Domain families : Smart (EMBL)SCY (SM00199)  
Conserved Domain (NCBI)CCL19
DMDM Disease mutations6363
Blocks (Seattle)CCL19
PDB (SRS)2MP1   
PDB (PDBSum)2MP1   
PDB (IMB)2MP1   
PDB (RSDB)2MP1   
Structural Biology KnowledgeBase2MP1   
SCOP (Structural Classification of Proteins)2MP1   
CATH (Classification of proteins structures)2MP1   
SuperfamilyQ99731
Human Protein AtlasENSG00000172724
Peptide AtlasQ99731
HPRD03750
IPIIPI00017761   IPI00479775   
Protein Interaction databases
DIP (DOE-UCLA)Q99731
IntAct (EBI)Q99731
FunCoupENSG00000172724
BioGRIDCCL19
STRING (EMBL)CCL19
ZODIACCCL19
Ontologies - Pathways
QuickGOQ99731
Ontology : AmiGOestablishment of T cell polarity  immunological synapse formation  dendritic cell chemotaxis  myeloid dendritic cell chemotaxis  monocyte chemotaxis  positive regulation of dendritic cell antigen processing and presentation  extracellular region  extracellular space  intracellular  intracellular  cell  cellular calcium ion homeostasis  inflammatory response  inflammatory response  immune response  cell communication  G-protein coupled receptor signaling pathway  activation of JUN kinase activity  chemokine activity  response to virus  positive regulation of glycoprotein biosynthetic process  T cell costimulation  CCR7 chemokine receptor binding  CCR10 chemokine receptor binding  positive regulation of interleukin-12 production  positive regulation of tumor necrosis factor production  response to prostaglandin E  positive regulation of T cell proliferation  positive regulation of NF-kappaB import into nucleus  chemokine receptor binding  positive regulation of I-kappaB kinase/NF-kappaB signaling  positive regulation of GTPase activity  positive regulation of GTPase activity  positive regulation of phosphatidylinositol 3-kinase activity  positive regulation of T-helper 1 cell differentiation  positive regulation of endocytosis  positive regulation of protein kinase activity  positive regulation of JNK cascade  CCR chemokine receptor binding  lymphocyte chemotaxis  positive regulation of receptor-mediated endocytosis  cell maturation  positive regulation of interleukin-1 beta secretion  positive regulation of chemotaxis  release of sequestered calcium ion into cytosol  positive regulation of protein kinase B signaling  regulation of cell projection assembly  chemokine-mediated signaling pathway  positive regulation of ERK1 and ERK2 cascade  positive regulation of ERK1 and ERK2 cascade  cellular response to interferon-gamma  cellular response to interleukin-1  cellular response to tumor necrosis factor  response to nitric oxide  interleukin-12 secretion  positive regulation of neutrophil chemotaxis  mature conventional dendritic cell differentiation  cellular response to virus  negative regulation of leukocyte apoptotic process  positive regulation of cell motility  positive regulation of dendritic cell dendrite assembly  
Ontology : EGO-EBIestablishment of T cell polarity  immunological synapse formation  dendritic cell chemotaxis  myeloid dendritic cell chemotaxis  monocyte chemotaxis  positive regulation of dendritic cell antigen processing and presentation  extracellular region  extracellular space  intracellular  intracellular  cell  cellular calcium ion homeostasis  inflammatory response  inflammatory response  immune response  cell communication  G-protein coupled receptor signaling pathway  activation of JUN kinase activity  chemokine activity  response to virus  positive regulation of glycoprotein biosynthetic process  T cell costimulation  CCR7 chemokine receptor binding  CCR10 chemokine receptor binding  positive regulation of interleukin-12 production  positive regulation of tumor necrosis factor production  response to prostaglandin E  positive regulation of T cell proliferation  positive regulation of NF-kappaB import into nucleus  chemokine receptor binding  positive regulation of I-kappaB kinase/NF-kappaB signaling  positive regulation of GTPase activity  positive regulation of GTPase activity  positive regulation of phosphatidylinositol 3-kinase activity  positive regulation of T-helper 1 cell differentiation  positive regulation of endocytosis  positive regulation of protein kinase activity  positive regulation of JNK cascade  CCR chemokine receptor binding  lymphocyte chemotaxis  positive regulation of receptor-mediated endocytosis  cell maturation  positive regulation of interleukin-1 beta secretion  positive regulation of chemotaxis  release of sequestered calcium ion into cytosol  positive regulation of protein kinase B signaling  regulation of cell projection assembly  chemokine-mediated signaling pathway  positive regulation of ERK1 and ERK2 cascade  positive regulation of ERK1 and ERK2 cascade  cellular response to interferon-gamma  cellular response to interleukin-1  cellular response to tumor necrosis factor  response to nitric oxide  interleukin-12 secretion  positive regulation of neutrophil chemotaxis  mature conventional dendritic cell differentiation  cellular response to virus  negative regulation of leukocyte apoptotic process  positive regulation of cell motility  positive regulation of dendritic cell dendrite assembly  
Pathways : KEGGCytokine-cytokine receptor interaction    Chemokine signaling pathway    NF-kappa B signaling pathway   
NDEx NetworkCCL19
Atlas of Cancer Signalling NetworkCCL19
Wikipedia pathwaysCCL19
Orthology - Evolution
OrthoDB6363
GeneTree (enSembl)ENSG00000172724
Phylogenetic Trees/Animal Genes : TreeFamCCL19
HOVERGENQ99731
HOGENOMQ99731
Homologs : HomoloGeneCCL19
Homology/Alignments : Family Browser (UCSC)CCL19
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCCL19 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CCL19
dbVarCCL19
ClinVarCCL19
1000_GenomesCCL19 
Exome Variant ServerCCL19
ExAC (Exome Aggregation Consortium)CCL19 (select the gene name)
Genetic variants : HAPMAP6363
Genomic Variants (DGV)CCL19 [DGVbeta]
DECIPHER (Syndromes)9:34689567-34691274  ENSG00000172724
CONAN: Copy Number AnalysisCCL19 
Mutations
ICGC Data PortalCCL19 
TCGA Data PortalCCL19 
Broad Tumor PortalCCL19
OASIS PortalCCL19 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCCL19  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCCL19
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CCL19
DgiDB (Drug Gene Interaction Database)CCL19
DoCM (Curated mutations)CCL19 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CCL19 (select a term)
intoGenCCL19
Cancer3DCCL19(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602227   
Orphanet
MedgenCCL19
Genetic Testing Registry CCL19
NextProtQ99731 [Medical]
TSGene6363
GENETestsCCL19
Huge Navigator CCL19 [HugePedia]
snp3D : Map Gene to Disease6363
BioCentury BCIQCCL19
ClinGenCCL19
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6363
Chemical/Pharm GKB GenePA35550
Clinical trialCCL19
Miscellaneous
canSAR (ICR)CCL19 (select the gene name)
Probes
Litterature
PubMed80 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCCL19
EVEXCCL19
GoPubMedCCL19
iHOPCCL19
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 14:55:21 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.