Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CCL23 (C-C motif chemokine ligand 23)

Identity

Alias_namesSCYA23
small inducible cytokine subfamily A (Cys-Cys), member 23
chemokine (C-C motif) ligand 23
Alias_symbol (synonym)Ckb-8
MPIF-1
MIP-3
CKb8
Other aliasCK-BETA-8
Ckb-8-1
MIP3
hmrp-2a
HGNC (Hugo) CCL23
LocusID (NCBI) 6368
Atlas_Id 50135
Location 17q12  [Link to chromosome band 17q12]
Location_base_pair Starts at 36013056 and ends at 36017968 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CCL23   10622
Cards
Entrez_Gene (NCBI)CCL23  6368  C-C motif chemokine ligand 23
AliasesCK-BETA-8; CKb8; Ckb-8; Ckb-8-1; 
MIP-3; MIP3; MPIF-1; SCYA23; hmrp-2a
GeneCards (Weizmann)CCL23
Ensembl hg19 (Hinxton)ENSG00000274736 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000274736 [Gene_View]  chr17:36013056-36017968 [Contig_View]  CCL23 [Vega]
ICGC DataPortalENSG00000274736
TCGA cBioPortalCCL23
AceView (NCBI)CCL23
Genatlas (Paris)CCL23
WikiGenes6368
SOURCE (Princeton)CCL23
Genetics Home Reference (NIH)CCL23
Genomic and cartography
GoldenPath hg38 (UCSC)CCL23  -     chr17:36013056-36017968 -  17q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CCL23  -     17q12   [Description]    (hg19-Feb_2009)
EnsemblCCL23 - 17q12 [CytoView hg19]  CCL23 - 17q12 [CytoView hg38]
Mapping of homologs : NCBICCL23 [Mapview hg19]  CCL23 [Mapview hg38]
OMIM602494   
Gene and transcription
Genbank (Entrez)BC093970 BC143310 BQ026575 U58913 U67128
RefSeq transcript (Entrez)NM_005064 NM_145898
RefSeq genomic (Entrez)NC_000017 NC_018928 NG_029876 NT_187614
Consensus coding sequences : CCDS (NCBI)CCL23
Cluster EST : UnigeneHs.169191 [ NCBI ]
CGAP (NCI)Hs.169191
Alternative Splicing GalleryENSG00000274736
Gene ExpressionCCL23 [ NCBI-GEO ]   CCL23 [ EBI - ARRAY_EXPRESS ]   CCL23 [ SEEK ]   CCL23 [ MEM ]
Gene Expression Viewer (FireBrowse)CCL23 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6368
GTEX Portal (Tissue expression)CCL23
Protein : pattern, domain, 3D structure
UniProt/SwissProtP55773   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP55773  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP55773
Splice isoforms : SwissVarP55773
PhosPhoSitePlusP55773
Domaine pattern : Prosite (Expaxy)SMALL_CYTOKINES_CC (PS00472)   
Domains : Interpro (EBI)Chemokine_CC_CS    Chemokine_IL8-like_dom   
Domain families : Pfam (Sanger)IL8 (PF00048)   
Domain families : Pfam (NCBI)pfam00048   
Domain families : Smart (EMBL)SCY (SM00199)  
Conserved Domain (NCBI)CCL23
DMDM Disease mutations6368
Blocks (Seattle)CCL23
PDB (SRS)1G91   
PDB (PDBSum)1G91   
PDB (IMB)1G91   
PDB (RSDB)1G91   
Structural Biology KnowledgeBase1G91   
SCOP (Structural Classification of Proteins)1G91   
CATH (Classification of proteins structures)1G91   
SuperfamilyP55773
Human Protein AtlasENSG00000274736
Peptide AtlasP55773
HPRD03930
IPIIPI00026179   IPI00221165   
Protein Interaction databases
DIP (DOE-UCLA)P55773
IntAct (EBI)P55773
FunCoupENSG00000274736
BioGRIDCCL23
STRING (EMBL)CCL23
ZODIACCCL23
Ontologies - Pathways
QuickGOP55773
Ontology : AmiGOmonocyte chemotaxis  monocyte chemotaxis  extracellular region  extracellular space  cell  cellular calcium ion homeostasis  chemotaxis  inflammatory response  immune response  signal transduction  G-protein coupled receptor signaling pathway  cell-cell signaling  chemokine activity  heparin binding  negative regulation of cell proliferation  neutrophil chemotaxis  CCR1 chemokine receptor binding  positive regulation of GTPase activity  lymphocyte chemotaxis  chemokine-mediated signaling pathway  positive regulation of ERK1 and ERK2 cascade  cellular response to interferon-gamma  cellular response to interleukin-1  cellular response to tumor necrosis factor  negative regulation of C-C chemokine binding  
Ontology : EGO-EBImonocyte chemotaxis  monocyte chemotaxis  extracellular region  extracellular space  cell  cellular calcium ion homeostasis  chemotaxis  inflammatory response  immune response  signal transduction  G-protein coupled receptor signaling pathway  cell-cell signaling  chemokine activity  heparin binding  negative regulation of cell proliferation  neutrophil chemotaxis  CCR1 chemokine receptor binding  positive regulation of GTPase activity  lymphocyte chemotaxis  chemokine-mediated signaling pathway  positive regulation of ERK1 and ERK2 cascade  cellular response to interferon-gamma  cellular response to interleukin-1  cellular response to tumor necrosis factor  negative regulation of C-C chemokine binding  
Pathways : KEGGCytokine-cytokine receptor interaction    Chemokine signaling pathway   
NDEx NetworkCCL23
Atlas of Cancer Signalling NetworkCCL23
Wikipedia pathwaysCCL23
Orthology - Evolution
OrthoDB6368
GeneTree (enSembl)ENSG00000274736
Phylogenetic Trees/Animal Genes : TreeFamCCL23
HOVERGENP55773
HOGENOMP55773
Homologs : HomoloGeneCCL23
Homology/Alignments : Family Browser (UCSC)CCL23
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCCL23 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CCL23
dbVarCCL23
ClinVarCCL23
1000_GenomesCCL23 
Exome Variant ServerCCL23
ExAC (Exome Aggregation Consortium)CCL23 (select the gene name)
Genetic variants : HAPMAP6368
Genomic Variants (DGV)CCL23 [DGVbeta]
DECIPHERCCL23 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCCL23 
Mutations
ICGC Data PortalCCL23 
TCGA Data PortalCCL23 
Broad Tumor PortalCCL23
OASIS PortalCCL23 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDCCL23
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CCL23
DgiDB (Drug Gene Interaction Database)CCL23
DoCM (Curated mutations)CCL23 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CCL23 (select a term)
intoGenCCL23
Cancer3DCCL23(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602494   
Orphanet
MedgenCCL23
Genetic Testing Registry CCL23
NextProtP55773 [Medical]
TSGene6368
GENETestsCCL23
Target ValidationCCL23
Huge Navigator CCL23 [HugePedia]
snp3D : Map Gene to Disease6368
BioCentury BCIQCCL23
ClinGenCCL23
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6368
Chemical/Pharm GKB GenePA35554
Clinical trialCCL23
Miscellaneous
canSAR (ICR)CCL23 (select the gene name)
Probes
Litterature
PubMed44 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCCL23
EVEXCCL23
GoPubMedCCL23
iHOPCCL23
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 16:57:03 CEST 2017

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