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CCL24 (C-C motif chemokine ligand 24)

Identity

Alias_namesSCYA24
small inducible cytokine subfamily A (Cys-Cys), member 24
chemokine (C-C motif) ligand 24
Alias_symbol (synonym)Ckb-6
MPIF-2
eotaxin-2
MPIF2
Other alias
HGNC (Hugo) CCL24
LocusID (NCBI) 6369
Atlas_Id 49958
Location 7q11.23  [Link to chromosome band 7q11]
Location_base_pair Starts at 75811796 and ends at 75813715 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CCL24   10623
Cards
Entrez_Gene (NCBI)CCL24  6369  C-C motif chemokine ligand 24
AliasesCkb-6; MPIF-2; MPIF2; SCYA24
GeneCards (Weizmann)CCL24
Ensembl hg19 (Hinxton)ENSG00000106178 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000106178 [Gene_View]  chr7:75811796-75813715 [Contig_View]  CCL24 [Vega]
ICGC DataPortalENSG00000106178
TCGA cBioPortalCCL24
AceView (NCBI)CCL24
Genatlas (Paris)CCL24
WikiGenes6369
SOURCE (Princeton)CCL24
Genetics Home Reference (NIH)CCL24
Genomic and cartography
GoldenPath hg38 (UCSC)CCL24  -     chr7:75811796-75813715 -  7q11.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CCL24  -     7q11.23   [Description]    (hg19-Feb_2009)
EnsemblCCL24 - 7q11.23 [CytoView hg19]  CCL24 - 7q11.23 [CytoView hg38]
Mapping of homologs : NCBICCL24 [Mapview hg19]  CCL24 [Mapview hg38]
OMIM602495   
Gene and transcription
Genbank (Entrez)AJ223461 AK312216 BC069072 BC069391 HQ448443
RefSeq transcript (Entrez)NM_002991
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CCL24
Cluster EST : UnigeneHs.247838 [ NCBI ]
CGAP (NCI)Hs.247838
Alternative Splicing GalleryENSG00000106178
Gene ExpressionCCL24 [ NCBI-GEO ]   CCL24 [ EBI - ARRAY_EXPRESS ]   CCL24 [ SEEK ]   CCL24 [ MEM ]
Gene Expression Viewer (FireBrowse)CCL24 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6369
GTEX Portal (Tissue expression)CCL24
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00175   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00175  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00175
Splice isoforms : SwissVarO00175
PhosPhoSitePlusO00175
Domains : Interpro (EBI)Chemokine_IL8-like_dom   
Domain families : Pfam (Sanger)IL8 (PF00048)   
Domain families : Pfam (NCBI)pfam00048   
Domain families : Smart (EMBL)SCY (SM00199)  
Conserved Domain (NCBI)CCL24
DMDM Disease mutations6369
Blocks (Seattle)CCL24
PDB (SRS)1EIG    1EIH   
PDB (PDBSum)1EIG    1EIH   
PDB (IMB)1EIG    1EIH   
PDB (RSDB)1EIG    1EIH   
Structural Biology KnowledgeBase1EIG    1EIH   
SCOP (Structural Classification of Proteins)1EIG    1EIH   
CATH (Classification of proteins structures)1EIG    1EIH   
SuperfamilyO00175
Human Protein AtlasENSG00000106178
Peptide AtlasO00175
HPRD03931
IPIIPI00010462   
Protein Interaction databases
DIP (DOE-UCLA)O00175
IntAct (EBI)O00175
FunCoupENSG00000106178
BioGRIDCCL24
STRING (EMBL)CCL24
ZODIACCCL24
Ontologies - Pathways
QuickGOO00175
Ontology : AmiGOpositive regulation of endothelial cell proliferation  monocyte chemotaxis  extracellular space  chemotaxis  inflammatory response  immune response  cytoskeleton organization  signal transduction  G-protein coupled receptor signaling pathway  cell-cell signaling  chemokine activity  regulation of cell shape  positive regulation of cell migration  neutrophil chemotaxis  positive regulation of actin filament polymerization  CCR3 chemokine receptor binding  positive regulation of GTPase activity  positive regulation of angiogenesis  receptor agonist activity  CCR chemokine receptor binding  eosinophil chemotaxis  lymphocyte chemotaxis  positive regulation of inflammatory response  chemokine-mediated signaling pathway  positive regulation of ERK1 and ERK2 cascade  cellular response to interferon-gamma  cellular response to interleukin-1  cellular response to tumor necrosis factor  positive regulation of eosinophil migration  
Ontology : EGO-EBIpositive regulation of endothelial cell proliferation  monocyte chemotaxis  extracellular space  chemotaxis  inflammatory response  immune response  cytoskeleton organization  signal transduction  G-protein coupled receptor signaling pathway  cell-cell signaling  chemokine activity  regulation of cell shape  positive regulation of cell migration  neutrophil chemotaxis  positive regulation of actin filament polymerization  CCR3 chemokine receptor binding  positive regulation of GTPase activity  positive regulation of angiogenesis  receptor agonist activity  CCR chemokine receptor binding  eosinophil chemotaxis  lymphocyte chemotaxis  positive regulation of inflammatory response  chemokine-mediated signaling pathway  positive regulation of ERK1 and ERK2 cascade  cellular response to interferon-gamma  cellular response to interleukin-1  cellular response to tumor necrosis factor  positive regulation of eosinophil migration  
Pathways : KEGGCytokine-cytokine receptor interaction    Chemokine signaling pathway   
NDEx NetworkCCL24
Atlas of Cancer Signalling NetworkCCL24
Wikipedia pathwaysCCL24
Orthology - Evolution
OrthoDB6369
GeneTree (enSembl)ENSG00000106178
Phylogenetic Trees/Animal Genes : TreeFamCCL24
HOVERGENO00175
HOGENOMO00175
Homologs : HomoloGeneCCL24
Homology/Alignments : Family Browser (UCSC)CCL24
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCCL24 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CCL24
dbVarCCL24
ClinVarCCL24
1000_GenomesCCL24 
Exome Variant ServerCCL24
ExAC (Exome Aggregation Consortium)CCL24 (select the gene name)
Genetic variants : HAPMAP6369
Genomic Variants (DGV)CCL24 [DGVbeta]
DECIPHERCCL24 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCCL24 
Mutations
ICGC Data PortalCCL24 
TCGA Data PortalCCL24 
Broad Tumor PortalCCL24
OASIS PortalCCL24 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCCL24  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCCL24
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CCL24
DgiDB (Drug Gene Interaction Database)CCL24
DoCM (Curated mutations)CCL24 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CCL24 (select a term)
intoGenCCL24
Cancer3DCCL24(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602495   
Orphanet
MedgenCCL24
Genetic Testing Registry CCL24
NextProtO00175 [Medical]
TSGene6369
GENETestsCCL24
Huge Navigator CCL24 [HugePedia]
snp3D : Map Gene to Disease6369
BioCentury BCIQCCL24
ClinGenCCL24
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6369
Chemical/Pharm GKB GenePA35555
Clinical trialCCL24
Miscellaneous
canSAR (ICR)CCL24 (select the gene name)
Probes
Litterature
PubMed58 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCCL24
EVEXCCL24
GoPubMedCCL24
iHOPCCL24
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:09:18 CEST 2017

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