CCL3L1 (C-C motif chemokine ligand 3 like 1)

2015-08-01  

Identity

HGNC
CCL3L1
LOCATION
17q12
LOCUSID
6349
ALIAS
464.2,D17S1718,G0S19-2,LD78,LD78-beta(1-70),LD78BETA,MIP1AP,SCYA3L,SCYA3L1

Other Information

Locus ID:

NCBI: 6349
MIM: 601395
HGNC: 10628

Variants:

dbSNP: 6349
ClinVar: 6349
COSMIC: CCL3L1

Pathways

PathwaySourceExternal ID
Cytokine-cytokine receptor interactionKEGGko04060
Toll-like receptor signaling pathwayKEGGko04620
Cytokine-cytokine receptor interactionKEGGhsa04060
Toll-like receptor signaling pathwayKEGGhsa04620
Chemokine signaling pathwayKEGGko04062
Chemokine signaling pathwayKEGGhsa04062
Chagas disease (American trypanosomiasis)KEGGko05142
Chagas disease (American trypanosomiasis)KEGGhsa05142
Rheumatoid arthritisKEGGko05323
Rheumatoid arthritisKEGGhsa05323
Salmonella infectionKEGGko05132
Salmonella infectionKEGGhsa05132
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Signaling by InterleukinsREACTOMER-HSA-449147
Interleukin-10 signalingREACTOMER-HSA-6783783

References

Pubmed IDYearTitleCitations
156372362005The influence of CCL3L1 gene-containing segmental duplications on HIV-1/AIDS susceptibility.437
179520792007CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entry-independent mechanisms.80
176042892008Evidence for an influence of chemokine ligand 3-like 1 (CCL3L1) gene copy number on susceptibility to rheumatoid arthritis.59
176042892008Evidence for an influence of chemokine ligand 3-like 1 (CCL3L1) gene copy number on susceptibility to rheumatoid arthritis.59
159622312005Genetic variations in the receptor-ligand pair CCR5 and CCL3L1 are important determinants of susceptibility to Kawasaki disease.35
197417162010Association of copy number variation in the FCGR3B gene with risk of autoimmune diseases.33
197417162010Association of copy number variation in the FCGR3B gene with risk of autoimmune diseases.33
198125622009Experimental aspects of copy number variant assays at CCL3L1.33
198125602009CCL3L1 and HIV/AIDS susceptibility.29
204426342010APOE epsilon4 and MBL-2 O/O genotypes are associated with neurocognitive impairment in HIV-infected plasma donors.29

Citation

Dessen P

CCL3L1 (C-C motif chemokine ligand 3 like 1)

Atlas Genet Cytogenet Oncol Haematol. 2015-08-01

Online version: http://atlasgeneticsoncology.org/gene/55347/ccl3l1