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CCL3L3 (C-C motif chemokine ligand 3 like 3)

Identity

Alias_nameschemokine (C-C motif) ligand 3-like 3
Alias_symbol (synonym)MGC12815
Other alias464.2
D17S1718
G0S19-2
LD78
LD78BETA
SCYA3L
SCYA3L1
HGNC (Hugo) CCL3L3
LocusID (NCBI) 414062
Atlas_Id 55379
Location 17q12  [Link to chromosome band 17q12]
Location_base_pair Starts at 36194870 and ends at 36196748 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CCL3L3   30554
Cards
Entrez_Gene (NCBI)CCL3L3  414062  C-C motif chemokine ligand 3 like 3
Aliases464.2; D17S1718; G0S19-2; LD78; 
LD78BETA; SCYA3L; SCYA3L1
GeneCards (Weizmann)CCL3L3
Ensembl hg19 (Hinxton)ENSG00000276085 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000276085 [Gene_View]  chr17:36194870-36196748 [Contig_View]  CCL3L3 [Vega]
ICGC DataPortalENSG00000276085
TCGA cBioPortalCCL3L3
AceView (NCBI)CCL3L3
Genatlas (Paris)CCL3L3
WikiGenes414062
SOURCE (Princeton)CCL3L3
Genetics Home Reference (NIH)CCL3L3
Genomic and cartography
GoldenPath hg38 (UCSC)CCL3L3  -     chr17:36194870-36196748 -  17q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CCL3L3  -     17q12   [Description]    (hg19-Feb_2009)
EnsemblCCL3L3 - 17q12 [CytoView hg19]  CCL3L3 - 17q12 [CytoView hg38]
Mapping of homologs : NCBICCL3L3 [Mapview hg19]  CCL3L3 [Mapview hg38]
OMIM609468   
Gene and transcription
Genbank (Entrez)AA380745 AI302038 BC007783 BC063472 BC146919
RefSeq transcript (Entrez)NM_001001437
RefSeq genomic (Entrez)NC_000017 NC_018928 NG_023325 NT_187614 NT_187661
Consensus coding sequences : CCDS (NCBI)CCL3L3
Cluster EST : UnigeneHs.454713 [ NCBI ]
CGAP (NCI)Hs.454713
Alternative Splicing GalleryENSG00000276085
Gene ExpressionCCL3L3 [ NCBI-GEO ]   CCL3L3 [ EBI - ARRAY_EXPRESS ]   CCL3L3 [ SEEK ]   CCL3L3 [ MEM ]
Gene Expression Viewer (FireBrowse)CCL3L3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)414062
GTEX Portal (Tissue expression)CCL3L3
Human Protein AtlasENSG00000276085-CCL3L3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP16619   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP16619  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP16619
Splice isoforms : SwissVarP16619
PhosPhoSitePlusP16619
Domaine pattern : Prosite (Expaxy)SMALL_CYTOKINES_CC (PS00472)   
Domains : Interpro (EBI)Chemokine_CC_CS    Chemokine_IL8-like_dom   
Domain families : Pfam (Sanger)IL8 (PF00048)   
Domain families : Pfam (NCBI)pfam00048   
Domain families : Smart (EMBL)SCY (SM00199)  
Conserved Domain (NCBI)CCL3L3
DMDM Disease mutations414062
Blocks (Seattle)CCL3L3
SuperfamilyP16619
Human Protein Atlas [tissue]ENSG00000276085-CCL3L3 [tissue]
Peptide AtlasP16619
HPRD14426
IPIIPI00029732   IPI00790938   IPI00953278   IPI00873927   
Protein Interaction databases
DIP (DOE-UCLA)P16619
IntAct (EBI)P16619
FunCoupENSG00000276085
BioGRIDCCL3L3
STRING (EMBL)CCL3L3
ZODIACCCL3L3
Ontologies - Pathways
QuickGOP16619
Ontology : AmiGOmonocyte chemotaxis  extracellular region  extracellular space  inflammatory response  inflammatory response  G-protein coupled receptor signaling pathway  chemokine activity  negative regulation of cell proliferation  neutrophil chemotaxis  positive regulation of GTPase activity  CCR chemokine receptor binding  lymphocyte chemotaxis  chemokine-mediated signaling pathway  positive regulation of ERK1 and ERK2 cascade  cellular response to interferon-gamma  cellular response to interleukin-1  cellular response to tumor necrosis factor  
Ontology : EGO-EBImonocyte chemotaxis  extracellular region  extracellular space  inflammatory response  inflammatory response  G-protein coupled receptor signaling pathway  chemokine activity  negative regulation of cell proliferation  neutrophil chemotaxis  positive regulation of GTPase activity  CCR chemokine receptor binding  lymphocyte chemotaxis  chemokine-mediated signaling pathway  positive regulation of ERK1 and ERK2 cascade  cellular response to interferon-gamma  cellular response to interleukin-1  cellular response to tumor necrosis factor  
Pathways : KEGGCytokine-cytokine receptor interaction    Chemokine signaling pathway    Toll-like receptor signaling pathway    Salmonella infection    Chagas disease (American trypanosomiasis)    Rheumatoid arthritis   
NDEx NetworkCCL3L3
Atlas of Cancer Signalling NetworkCCL3L3
Wikipedia pathwaysCCL3L3
Orthology - Evolution
OrthoDB414062
GeneTree (enSembl)ENSG00000276085
Phylogenetic Trees/Animal Genes : TreeFamCCL3L3
HOVERGENP16619
HOGENOMP16619
Homologs : HomoloGeneCCL3L3
Homology/Alignments : Family Browser (UCSC)CCL3L3
Gene fusions - Rearrangements
Fusion: Tumor Portal CCL3L3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCCL3L3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CCL3L3
dbVarCCL3L3
ClinVarCCL3L3
1000_GenomesCCL3L3 
Exome Variant ServerCCL3L3
ExAC (Exome Aggregation Consortium)ENSG00000276085
GNOMAD BrowserENSG00000276085
Genetic variants : HAPMAP414062
Genomic Variants (DGV)CCL3L3 [DGVbeta]
DECIPHERCCL3L3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCCL3L3 
Mutations
ICGC Data PortalCCL3L3 
TCGA Data PortalCCL3L3 
Broad Tumor PortalCCL3L3
OASIS PortalCCL3L3 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDCCL3L3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CCL3L3
DgiDB (Drug Gene Interaction Database)CCL3L3
DoCM (Curated mutations)CCL3L3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CCL3L3 (select a term)
intoGenCCL3L3
Cancer3DCCL3L3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609468   
Orphanet
MedgenCCL3L3
Genetic Testing Registry CCL3L3
NextProtP16619 [Medical]
TSGene414062
GENETestsCCL3L3
Target ValidationCCL3L3
Huge Navigator CCL3L3 [HugePedia]
snp3D : Map Gene to Disease414062
BioCentury BCIQCCL3L3
ClinGenCCL3L3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD414062
Chemical/Pharm GKB GenePA142672174
Clinical trialCCL3L3
Miscellaneous
canSAR (ICR)CCL3L3 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCCL3L3
EVEXCCL3L3
GoPubMedCCL3L3
iHOPCCL3L3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 12:43:31 CET 2017

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