Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CCL7 (C-C motif chemokine ligand 7)

Identity

Alias_namesSCYA6
SCYA7
small inducible cytokine A7 (monocyte chemotactic protein 3)
chemokine (C-C motif) ligand 7
Alias_symbol (synonym)MCP-3
NC28
FIC
MARC
MCP3
Other alias
HGNC (Hugo) CCL7
LocusID (NCBI) 6354
Atlas_Id 946
Location 17q12  [Link to chromosome band 17q12]
Location_base_pair Starts at 32597235 and ends at 32599261 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CCL7   10634
Cards
Entrez_Gene (NCBI)CCL7  6354  C-C motif chemokine ligand 7
AliasesFIC; MARC; MCP-3; MCP3; 
NC28; SCYA6; SCYA7
GeneCards (Weizmann)CCL7
Ensembl hg19 (Hinxton)ENSG00000108688 [Gene_View]  chr17:32597235-32599261 [Contig_View]  CCL7 [Vega]
Ensembl hg38 (Hinxton)ENSG00000108688 [Gene_View]  chr17:32597235-32599261 [Contig_View]  CCL7 [Vega]
ICGC DataPortalENSG00000108688
TCGA cBioPortalCCL7
AceView (NCBI)CCL7
Genatlas (Paris)CCL7
WikiGenes6354
SOURCE (Princeton)CCL7
Genetics Home Reference (NIH)CCL7
Genomic and cartography
GoldenPath hg19 (UCSC)CCL7  -     chr17:32597235-32599261 +  17q12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CCL7  -     17q12   [Description]    (hg38-Dec_2013)
EnsemblCCL7 - 17q12 [CytoView hg19]  CCL7 - 17q12 [CytoView hg38]
Mapping of homologs : NCBICCL7 [Mapview hg19]  CCL7 [Mapview hg38]
OMIM158106   
Gene and transcription
Genbank (Entrez)AF043338 BC070240 BC092436 BC112258 BC112260
RefSeq transcript (Entrez)NM_006273
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010783 NW_004929407
Consensus coding sequences : CCDS (NCBI)CCL7
Cluster EST : UnigeneHs.251526 [ NCBI ]
CGAP (NCI)Hs.251526
Alternative Splicing GalleryENSG00000108688
Gene ExpressionCCL7 [ NCBI-GEO ]   CCL7 [ EBI - ARRAY_EXPRESS ]   CCL7 [ SEEK ]   CCL7 [ MEM ]
Gene Expression Viewer (FireBrowse)CCL7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6354
GTEX Portal (Tissue expression)CCL7
Protein : pattern, domain, 3D structure
UniProt/SwissProtP80098   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP80098  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP80098
Splice isoforms : SwissVarP80098
PhosPhoSitePlusP80098
Domaine pattern : Prosite (Expaxy)SMALL_CYTOKINES_CC (PS00472)   
Domains : Interpro (EBI)Chemokine_CC_CS    Chemokine_IL8-like_dom   
Domain families : Pfam (Sanger)IL8 (PF00048)   
Domain families : Pfam (NCBI)pfam00048   
Domain families : Smart (EMBL)SCY (SM00199)  
Conserved Domain (NCBI)CCL7
DMDM Disease mutations6354
Blocks (Seattle)CCL7
PDB (SRS)1BO0    1NCV    4ZKC   
PDB (PDBSum)1BO0    1NCV    4ZKC   
PDB (IMB)1BO0    1NCV    4ZKC   
PDB (RSDB)1BO0    1NCV    4ZKC   
Structural Biology KnowledgeBase1BO0    1NCV    4ZKC   
SCOP (Structural Classification of Proteins)1BO0    1NCV    4ZKC   
CATH (Classification of proteins structures)1BO0    1NCV    4ZKC   
SuperfamilyP80098
Human Protein AtlasENSG00000108688
Peptide AtlasP80098
HPRD01150
IPIIPI00746376   IPI00007563   IPI00797274   IPI00797857   
Protein Interaction databases
DIP (DOE-UCLA)P80098
IntAct (EBI)P80098
FunCoupENSG00000108688
BioGRIDCCL7
STRING (EMBL)CCL7
ZODIACCCL7
Ontologies - Pathways
QuickGOP80098
Ontology : AmiGOmonocyte chemotaxis  monocyte chemotaxis  protein binding  extracellular region  extracellular space  cell  cellular calcium ion homeostasis  chemotaxis  inflammatory response  cytoskeleton organization  signal transduction  G-protein coupled receptor signaling pathway  cell-cell signaling  chemokine activity  heparin binding  regulation of cell shape  response to gamma radiation  positive regulation of cell migration  neutrophil chemotaxis  CCR1 chemokine receptor binding  CCR2 chemokine receptor binding  positive regulation of GTPase activity  eosinophil chemotaxis  positive regulation of inflammatory response  chemokine-mediated signaling pathway  positive regulation of ERK1 and ERK2 cascade  cellular response to interferon-gamma  cellular response to interleukin-1  cellular response to tumor necrosis factor  cellular response to ethanol  positive regulation of natural killer cell chemotaxis  
Ontology : EGO-EBImonocyte chemotaxis  monocyte chemotaxis  protein binding  extracellular region  extracellular space  cell  cellular calcium ion homeostasis  chemotaxis  inflammatory response  cytoskeleton organization  signal transduction  G-protein coupled receptor signaling pathway  cell-cell signaling  chemokine activity  heparin binding  regulation of cell shape  response to gamma radiation  positive regulation of cell migration  neutrophil chemotaxis  CCR1 chemokine receptor binding  CCR2 chemokine receptor binding  positive regulation of GTPase activity  eosinophil chemotaxis  positive regulation of inflammatory response  chemokine-mediated signaling pathway  positive regulation of ERK1 and ERK2 cascade  cellular response to interferon-gamma  cellular response to interleukin-1  cellular response to tumor necrosis factor  cellular response to ethanol  positive regulation of natural killer cell chemotaxis  
Pathways : KEGGCytokine-cytokine receptor interaction    Chemokine signaling pathway   
NDEx NetworkCCL7
Atlas of Cancer Signalling NetworkCCL7
Wikipedia pathwaysCCL7
Orthology - Evolution
OrthoDB6354
GeneTree (enSembl)ENSG00000108688
Phylogenetic Trees/Animal Genes : TreeFamCCL7
HOVERGENP80098
HOGENOMP80098
Homologs : HomoloGeneCCL7
Homology/Alignments : Family Browser (UCSC)CCL7
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCCL7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CCL7
dbVarCCL7
ClinVarCCL7
1000_GenomesCCL7 
Exome Variant ServerCCL7
ExAC (Exome Aggregation Consortium)CCL7 (select the gene name)
Genetic variants : HAPMAP6354
Genomic Variants (DGV)CCL7 [DGVbeta]
DECIPHER (Syndromes)17:32597235-32599261  ENSG00000108688
CONAN: Copy Number AnalysisCCL7 
Mutations
ICGC Data PortalCCL7 
TCGA Data PortalCCL7 
Broad Tumor PortalCCL7
OASIS PortalCCL7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCCL7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCCL7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CCL7
DgiDB (Drug Gene Interaction Database)CCL7
DoCM (Curated mutations)CCL7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CCL7 (select a term)
intoGenCCL7
Cancer3DCCL7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM158106   
Orphanet
MedgenCCL7
Genetic Testing Registry CCL7
NextProtP80098 [Medical]
TSGene6354
GENETestsCCL7
Huge Navigator CCL7 [HugePedia]
snp3D : Map Gene to Disease6354
BioCentury BCIQCCL7
ClinGenCCL7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6354
Chemical/Pharm GKB GenePA35566
Clinical trialCCL7
Miscellaneous
canSAR (ICR)CCL7 (select the gene name)
Probes
Litterature
PubMed86 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCCL7
EVEXCCL7
GoPubMedCCL7
iHOPCCL7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:59:08 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.