CCN4 (cellular communication network factor 4)

2018-11-01  

Identity

HGNC
LOCATION
8q24.22
LOCUSID
ALIAS
WISP1,WISP1-OT1,WISP1-UT1,WISP1c,WISP1i,WISP1tc

Other Information

Locus ID:

NCBI: 8840
MIM: 603398
HGNC: 12769
Ensembl: ENSG00000104415

Variants:

dbSNP: 8840
ClinVar: 8840
TCGA: ENSG00000104415
COSMIC: CCN4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000104415ENST00000220856O95388
ENSG00000104415ENST00000250160O95388
ENSG00000104415ENST00000377862E5RG88
ENSG00000104415ENST00000517423O95388
ENSG00000104415ENST00000519433O95388

References

Pubmed IDYearTitleCitations
192870972009WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis.192
180068282007Activation of hepatic stem cell marker EpCAM by Wnt-beta-catenin signaling in hepatocellular carcinoma.152
117514172001Elevated levels of connective tissue growth factor, WISP-1, and CYR61 in primary breast cancers associated with more advanced features.101
192400612009Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.75
175797082007Expression of Cyr61, CTGF, and WISP-1 correlates with clinical features of lung cancer.62
191804792009Involvement of the Wnt signaling pathway in experimental and human osteoarthritis: prominent role of Wnt-induced signaling protein 1.62
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
200746382010WNT1-inducible signaling pathway protein-1 activates diverse cell survival pathways and blocks doxorubicin-induced cardiomyocyte death.52
206840292011WISP-1/CCN4 regulates osteogenesis by enhancing BMP-2 activity.49
128052222003Regulation of the Wnt signaling pathway by disabled-2 (Dab2).41

Citation

Dessen P

CCN4 (cellular communication network factor 4)

Atlas Genet Cytogenet Oncol Haematol. 2018-11-01

Online version: http://atlasgeneticsoncology.org/gene/57642/ccn4