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CCNA2 (cyclin A2)

Identity

Alias_namesCCNA
CCN1
Other alias
HGNC (Hugo) CCNA2
LocusID (NCBI) 890
Atlas_Id 950
Location 4q27  [Link to chromosome band 4q27]
Location_base_pair Starts at 122737599 and ends at 122745088 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(2;2)(p22;p22) LTBP1/BIRC6::del(2)(p22p22) LTBP1/BIRC6


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  Head and Neck: Laryngeal tumors: an overview
t(2;2)(p22;p22) LTBP1/BIRC6::del(2)(p22p22) LTBP1/BIRC6


External links

Nomenclature
HGNC (Hugo)CCNA2   1578
Cards
Entrez_Gene (NCBI)CCNA2  890  cyclin A2
AliasesCCN1; CCNA
GeneCards (Weizmann)CCNA2
Ensembl hg19 (Hinxton)ENSG00000145386 [Gene_View]  chr4:122737599-122745088 [Contig_View]  CCNA2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000145386 [Gene_View]  chr4:122737599-122745088 [Contig_View]  CCNA2 [Vega]
ICGC DataPortalENSG00000145386
TCGA cBioPortalCCNA2
AceView (NCBI)CCNA2
Genatlas (Paris)CCNA2
WikiGenes890
SOURCE (Princeton)CCNA2
Genetics Home Reference (NIH)CCNA2
Genomic and cartography
GoldenPath hg19 (UCSC)CCNA2  -     chr4:122737599-122745088 -  4q27   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CCNA2  -     4q27   [Description]    (hg38-Dec_2013)
EnsemblCCNA2 - 4q27 [CytoView hg19]  CCNA2 - 4q27 [CytoView hg38]
Mapping of homologs : NCBICCNA2 [Mapview hg19]  CCNA2 [Mapview hg38]
OMIM123835   
Gene and transcription
Genbank (Entrez)AK291931 AW276578 BC104783 BC104787 CR407692
RefSeq transcript (Entrez)NM_001237
RefSeq genomic (Entrez)NC_000004 NC_018915 NT_016354 NW_004929320
Consensus coding sequences : CCDS (NCBI)CCNA2
Cluster EST : UnigeneHs.58974 [ NCBI ]
CGAP (NCI)Hs.58974
Alternative Splicing GalleryENSG00000145386
Gene ExpressionCCNA2 [ NCBI-GEO ]   CCNA2 [ EBI - ARRAY_EXPRESS ]   CCNA2 [ SEEK ]   CCNA2 [ MEM ]
Gene Expression Viewer (FireBrowse)CCNA2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)890
GTEX Portal (Tissue expression)CCNA2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP20248   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP20248  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP20248
Splice isoforms : SwissVarP20248
PhosPhoSitePlusP20248
Domaine pattern : Prosite (Expaxy)CYCLINS (PS00292)   
Domains : Interpro (EBI)Cyclin-A_N    Cyclin-like    Cyclin_A2_chordates    Cyclin_C-dom    Cyclin_N   
Domain families : Pfam (Sanger)Cyclin_C (PF02984)    Cyclin_N (PF00134)    Cyclin_N2 (PF16500)   
Domain families : Pfam (NCBI)pfam02984    pfam00134    pfam16500   
Domain families : Smart (EMBL)CYCLIN (SM00385)  
Conserved Domain (NCBI)CCNA2
DMDM Disease mutations890
Blocks (Seattle)CCNA2
PDB (SRS)1E9H    1FIN    1FVV    1GY3    1H1P    1H1Q    1H1R    1H1S    1H24    1H25    1H26    1H27    1H28    1JST    1JSU    1OGU    1OI9    1OIU    1OIY    1OKV    1OKW    1OL1    1OL2    1P5E    1PKD    1QMZ    1URC    1VYW    2BKZ    2BPM    2C4G    2C5N    2C5O    2C5V    2C5X    2C6T    2CCH    2CCI    2CJM    2I40    2IW6    2IW8    2IW9    2UUE    2UZB    2UZD    2UZE    2UZL    2V22    2WEV    2WFY    2WHB    2WIH    2WIP    2WMA    2WMB    2WPA    2WXV    2X1N    3EID    3EJ1    3EOC    3F5X    4BCK    4BCM    4BCN    4BCP    4CFM    4CFN    4CFU    4CFV    4CFW    4CFX    4EOI    4EOJ    4EOK    4EOL    4EOM    4EON    4EOO    4EOP    4EOQ    4EOR    4EOS    4FX3    5CYI   
PDB (PDBSum)1E9H    1FIN    1FVV    1GY3    1H1P    1H1Q    1H1R    1H1S    1H24    1H25    1H26    1H27    1H28    1JST    1JSU    1OGU    1OI9    1OIU    1OIY    1OKV    1OKW    1OL1    1OL2    1P5E    1PKD    1QMZ    1URC    1VYW    2BKZ    2BPM    2C4G    2C5N    2C5O    2C5V    2C5X    2C6T    2CCH    2CCI    2CJM    2I40    2IW6    2IW8    2IW9    2UUE    2UZB    2UZD    2UZE    2UZL    2V22    2WEV    2WFY    2WHB    2WIH    2WIP    2WMA    2WMB    2WPA    2WXV    2X1N    3EID    3EJ1    3EOC    3F5X    4BCK    4BCM    4BCN    4BCP    4CFM    4CFN    4CFU    4CFV    4CFW    4CFX    4EOI    4EOJ    4EOK    4EOL    4EOM    4EON    4EOO    4EOP    4EOQ    4EOR    4EOS    4FX3    5CYI   
PDB (IMB)1E9H    1FIN    1FVV    1GY3    1H1P    1H1Q    1H1R    1H1S    1H24    1H25    1H26    1H27    1H28    1JST    1JSU    1OGU    1OI9    1OIU    1OIY    1OKV    1OKW    1OL1    1OL2    1P5E    1PKD    1QMZ    1URC    1VYW    2BKZ    2BPM    2C4G    2C5N    2C5O    2C5V    2C5X    2C6T    2CCH    2CCI    2CJM    2I40    2IW6    2IW8    2IW9    2UUE    2UZB    2UZD    2UZE    2UZL    2V22    2WEV    2WFY    2WHB    2WIH    2WIP    2WMA    2WMB    2WPA    2WXV    2X1N    3EID    3EJ1    3EOC    3F5X    4BCK    4BCM    4BCN    4BCP    4CFM    4CFN    4CFU    4CFV    4CFW    4CFX    4EOI    4EOJ    4EOK    4EOL    4EOM    4EON    4EOO    4EOP    4EOQ    4EOR    4EOS    4FX3    5CYI   
PDB (RSDB)1E9H    1FIN    1FVV    1GY3    1H1P    1H1Q    1H1R    1H1S    1H24    1H25    1H26    1H27    1H28    1JST    1JSU    1OGU    1OI9    1OIU    1OIY    1OKV    1OKW    1OL1    1OL2    1P5E    1PKD    1QMZ    1URC    1VYW    2BKZ    2BPM    2C4G    2C5N    2C5O    2C5V    2C5X    2C6T    2CCH    2CCI    2CJM    2I40    2IW6    2IW8    2IW9    2UUE    2UZB    2UZD    2UZE    2UZL    2V22    2WEV    2WFY    2WHB    2WIH    2WIP    2WMA    2WMB    2WPA    2WXV    2X1N    3EID    3EJ1    3EOC    3F5X    4BCK    4BCM    4BCN    4BCP    4CFM    4CFN    4CFU    4CFV    4CFW    4CFX    4EOI    4EOJ    4EOK    4EOL    4EOM    4EON    4EOO    4EOP    4EOQ    4EOR    4EOS    4FX3    5CYI   
Structural Biology KnowledgeBase1E9H    1FIN    1FVV    1GY3    1H1P    1H1Q    1H1R    1H1S    1H24    1H25    1H26    1H27    1H28    1JST    1JSU    1OGU    1OI9    1OIU    1OIY    1OKV    1OKW    1OL1    1OL2    1P5E    1PKD    1QMZ    1URC    1VYW    2BKZ    2BPM    2C4G    2C5N    2C5O    2C5V    2C5X    2C6T    2CCH    2CCI    2CJM    2I40    2IW6    2IW8    2IW9    2UUE    2UZB    2UZD    2UZE    2UZL    2V22    2WEV    2WFY    2WHB    2WIH    2WIP    2WMA    2WMB    2WPA    2WXV    2X1N    3EID    3EJ1    3EOC    3F5X    4BCK    4BCM    4BCN    4BCP    4CFM    4CFN    4CFU    4CFV    4CFW    4CFX    4EOI    4EOJ    4EOK    4EOL    4EOM    4EON    4EOO    4EOP    4EOQ    4EOR    4EOS    4FX3    5CYI   
SCOP (Structural Classification of Proteins)1E9H    1FIN    1FVV    1GY3    1H1P    1H1Q    1H1R    1H1S    1H24    1H25    1H26    1H27    1H28    1JST    1JSU    1OGU    1OI9    1OIU    1OIY    1OKV    1OKW    1OL1    1OL2    1P5E    1PKD    1QMZ    1URC    1VYW    2BKZ    2BPM    2C4G    2C5N    2C5O    2C5V    2C5X    2C6T    2CCH    2CCI    2CJM    2I40    2IW6    2IW8    2IW9    2UUE    2UZB    2UZD    2UZE    2UZL    2V22    2WEV    2WFY    2WHB    2WIH    2WIP    2WMA    2WMB    2WPA    2WXV    2X1N    3EID    3EJ1    3EOC    3F5X    4BCK    4BCM    4BCN    4BCP    4CFM    4CFN    4CFU    4CFV    4CFW    4CFX    4EOI    4EOJ    4EOK    4EOL    4EOM    4EON    4EOO    4EOP    4EOQ    4EOR    4EOS    4FX3    5CYI   
CATH (Classification of proteins structures)1E9H    1FIN    1FVV    1GY3    1H1P    1H1Q    1H1R    1H1S    1H24    1H25    1H26    1H27    1H28    1JST    1JSU    1OGU    1OI9    1OIU    1OIY    1OKV    1OKW    1OL1    1OL2    1P5E    1PKD    1QMZ    1URC    1VYW    2BKZ    2BPM    2C4G    2C5N    2C5O    2C5V    2C5X    2C6T    2CCH    2CCI    2CJM    2I40    2IW6    2IW8    2IW9    2UUE    2UZB    2UZD    2UZE    2UZL    2V22    2WEV    2WFY    2WHB    2WIH    2WIP    2WMA    2WMB    2WPA    2WXV    2X1N    3EID    3EJ1    3EOC    3F5X    4BCK    4BCM    4BCN    4BCP    4CFM    4CFN    4CFU    4CFV    4CFW    4CFX    4EOI    4EOJ    4EOK    4EOL    4EOM    4EON    4EOO    4EOP    4EOQ    4EOR    4EOS    4FX3    5CYI   
SuperfamilyP20248
Human Protein AtlasENSG00000145386
Peptide AtlasP20248
HPRD00453
IPIIPI00022865   
Protein Interaction databases
DIP (DOE-UCLA)P20248
IntAct (EBI)P20248
FunCoupENSG00000145386
BioGRIDCCNA2
STRING (EMBL)CCNA2
ZODIACCCNA2
Ontologies - Pathways
QuickGOP20248
Ontology : AmiGOregulation of cyclin-dependent protein serine/threonine kinase activity  female pronucleus  male pronucleus  protein binding  nucleus  nucleoplasm  nucleoplasm  cytoplasm  Golgi apparatus  mitotic nuclear division  mitotic G2 DNA damage checkpoint  Ras protein signal transduction  viral process  protein kinase binding  organ regeneration  response to glucagon  cellular response to platelet-derived growth factor stimulus  cellular response to leptin stimulus  positive regulation of transcription, DNA-templated  positive regulation of fibroblast proliferation  cell division  cellular response to cocaine  cellular response to luteinizing hormone stimulus  cellular response to estradiol stimulus  cellular response to hypoxia  cellular response to nitric oxide  cochlea development  cellular response to insulin-like growth factor stimulus  
Ontology : EGO-EBIregulation of cyclin-dependent protein serine/threonine kinase activity  female pronucleus  male pronucleus  protein binding  nucleus  nucleoplasm  nucleoplasm  cytoplasm  Golgi apparatus  mitotic nuclear division  mitotic G2 DNA damage checkpoint  Ras protein signal transduction  viral process  protein kinase binding  organ regeneration  response to glucagon  cellular response to platelet-derived growth factor stimulus  cellular response to leptin stimulus  positive regulation of transcription, DNA-templated  positive regulation of fibroblast proliferation  cell division  cellular response to cocaine  cellular response to luteinizing hormone stimulus  cellular response to estradiol stimulus  cellular response to hypoxia  cellular response to nitric oxide  cochlea development  cellular response to insulin-like growth factor stimulus  
Pathways : KEGGCell cycle    Progesterone-mediated oocyte maturation    Hepatitis B    Epstein-Barr virus infection    Viral carcinogenesis   
NDEx NetworkCCNA2
Atlas of Cancer Signalling NetworkCCNA2
Wikipedia pathwaysCCNA2
Orthology - Evolution
OrthoDB890
GeneTree (enSembl)ENSG00000145386
Phylogenetic Trees/Animal Genes : TreeFamCCNA2
HOVERGENP20248
HOGENOMP20248
Homologs : HomoloGeneCCNA2
Homology/Alignments : Family Browser (UCSC)CCNA2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCCNA2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CCNA2
dbVarCCNA2
ClinVarCCNA2
1000_GenomesCCNA2 
Exome Variant ServerCCNA2
ExAC (Exome Aggregation Consortium)CCNA2 (select the gene name)
Genetic variants : HAPMAP890
Genomic Variants (DGV)CCNA2 [DGVbeta]
DECIPHER (Syndromes)4:122737599-122745088  ENSG00000145386
CONAN: Copy Number AnalysisCCNA2 
Mutations
ICGC Data PortalCCNA2 
TCGA Data PortalCCNA2 
Broad Tumor PortalCCNA2
OASIS PortalCCNA2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCCNA2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCCNA2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CCNA2
DgiDB (Drug Gene Interaction Database)CCNA2
DoCM (Curated mutations)CCNA2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CCNA2 (select a term)
intoGenCCNA2
Cancer3DCCNA2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM123835   
Orphanet
MedgenCCNA2
Genetic Testing Registry CCNA2
NextProtP20248 [Medical]
TSGene890
GENETestsCCNA2
Huge Navigator CCNA2 [HugePedia]
snp3D : Map Gene to Disease890
BioCentury BCIQCCNA2
ClinGenCCNA2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD890
Chemical/Pharm GKB GenePA94
Clinical trialCCNA2
Miscellaneous
canSAR (ICR)CCNA2 (select the gene name)
Probes
Litterature
PubMed263 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCCNA2
EVEXCCNA2
GoPubMedCCNA2
iHOPCCNA2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:59:09 CET 2017

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