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CCNB3 (cyclin B3)

Identity

Other alias-
HGNC (Hugo) CCNB3
LocusID (NCBI) 85417
Atlas_Id 46654
Location Xp11.22  [Link to chromosome band Xp11]
Location_base_pair Starts at 50284540 and ends at 50351912 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BCOR (Xp11.4) / CCNB3 (Xp11.22)PPP4R1 (18p11.22) / CCNB3 (Xp11.22)PPP4R1 18p11.22 / CCNB3 Xp11.22

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  Bone: Sarcoma with inv(X)(p11.4p11.22) BCOR/CCNB3
Soft tissue tumors: an overview
t(X;18)(p11;p11) PPP4R1/CCNB3


External links

Nomenclature
HGNC (Hugo)CCNB3   18709
Cards
Entrez_Gene (NCBI)CCNB3  85417  cyclin B3
Aliases
GeneCards (Weizmann)CCNB3
Ensembl hg19 (Hinxton)ENSG00000147082 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000147082 [Gene_View]  ENSG00000147082 [Sequence]  chrX:50284540-50351912 [Contig_View]  CCNB3 [Vega]
ICGC DataPortalENSG00000147082
TCGA cBioPortalCCNB3
AceView (NCBI)CCNB3
Genatlas (Paris)CCNB3
WikiGenes85417
SOURCE (Princeton)CCNB3
Genetics Home Reference (NIH)CCNB3
Genomic and cartography
GoldenPath hg38 (UCSC)CCNB3  -     chrX:50284540-50351912 +  Xp11.22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CCNB3  -     Xp11.22   [Description]    (hg19-Feb_2009)
EnsemblCCNB3 - Xp11.22 [CytoView hg19]  CCNB3 - Xp11.22 [CytoView hg38]
Mapping of homologs : NCBICCNB3 [Mapview hg19]  CCNB3 [Mapview hg38]
OMIM300456   
Gene and transcription
Genbank (Entrez)AJ314764 AJ314765 AJ314766 AJ416458 AJ421672
RefSeq transcript (Entrez)NM_033031 NM_033670 NM_033671
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CCNB3
Cluster EST : UnigeneHs.740165 [ NCBI ]
CGAP (NCI)Hs.740165
Alternative Splicing GalleryENSG00000147082
Gene ExpressionCCNB3 [ NCBI-GEO ]   CCNB3 [ EBI - ARRAY_EXPRESS ]   CCNB3 [ SEEK ]   CCNB3 [ MEM ]
Gene Expression Viewer (FireBrowse)CCNB3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)85417
GTEX Portal (Tissue expression)CCNB3
Human Protein AtlasENSG00000147082-CCNB3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WWL7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WWL7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WWL7
Splice isoforms : SwissVarQ8WWL7
PhosPhoSitePlusQ8WWL7
Domains : Interpro (EBI)Cyclin-like    Cyclin-like_sf    Cyclin_B3    Cyclin_C-dom    Cyclin_N   
Domain families : Pfam (Sanger)Cyclin_C (PF02984)    Cyclin_N (PF00134)   
Domain families : Pfam (NCBI)pfam02984    pfam00134   
Domain families : Smart (EMBL)CYCLIN (SM00385)  Cyclin_C (SM01332)  
Conserved Domain (NCBI)CCNB3
DMDM Disease mutations85417
Blocks (Seattle)CCNB3
SuperfamilyQ8WWL7
Human Protein Atlas [tissue]ENSG00000147082-CCNB3 [tissue]
Peptide AtlasQ8WWL7
HPRD02350
IPIIPI00152849   IPI00066473   IPI00070367   
Protein Interaction databases
DIP (DOE-UCLA)Q8WWL7
IntAct (EBI)Q8WWL7
FunCoupENSG00000147082
BioGRIDCCNB3
STRING (EMBL)CCNB3
ZODIACCCNB3
Ontologies - Pathways
QuickGOQ8WWL7
Ontology : AmiGOregulation of cyclin-dependent protein serine/threonine kinase activity  regulation of cyclin-dependent protein serine/threonine kinase activity  mitotic cell cycle  cyclin-dependent protein kinase holoenzyme complex  protein kinase activity  protein binding  nucleus  cytoplasm  centrosome  regulation of mitotic nuclear division  positive regulation of cell proliferation  regulation of G2/M transition of mitotic cell cycle  cyclin-dependent protein serine/threonine kinase regulator activity  nuclear speck  protein kinase binding  protein kinase binding  positive regulation of cell cycle  cell division  meiotic cell cycle  
Ontology : EGO-EBIregulation of cyclin-dependent protein serine/threonine kinase activity  regulation of cyclin-dependent protein serine/threonine kinase activity  mitotic cell cycle  cyclin-dependent protein kinase holoenzyme complex  protein kinase activity  protein binding  nucleus  cytoplasm  centrosome  regulation of mitotic nuclear division  positive regulation of cell proliferation  regulation of G2/M transition of mitotic cell cycle  cyclin-dependent protein serine/threonine kinase regulator activity  nuclear speck  protein kinase binding  protein kinase binding  positive regulation of cell cycle  cell division  meiotic cell cycle  
Pathways : KEGGFoxO signaling pathway    Cell cycle    p53 signaling pathway    Progesterone-mediated oocyte maturation   
NDEx NetworkCCNB3
Atlas of Cancer Signalling NetworkCCNB3
Wikipedia pathwaysCCNB3
Orthology - Evolution
OrthoDB85417
GeneTree (enSembl)ENSG00000147082
Phylogenetic Trees/Animal Genes : TreeFamCCNB3
HOVERGENQ8WWL7
HOGENOMQ8WWL7
Homologs : HomoloGeneCCNB3
Homology/Alignments : Family Browser (UCSC)CCNB3
Gene fusions - Rearrangements
Fusion : MitelmanBCOR/CCNB3 [Xp11.4/Xp11.22]  [inv(X)(p11p11)]  [t(X;X)(p11;p11)]  
Fusion : MitelmanPPP4R1/CCNB3 [18p11.22/Xp11.22]  [t(X;18)(p11;p11)]  
Fusion PortalPPP4R1 18p11.22 CCNB3 Xp11.22 BRCA
Fusion : QuiverCCNB3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCCNB3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CCNB3
dbVarCCNB3
ClinVarCCNB3
1000_GenomesCCNB3 
Exome Variant ServerCCNB3
ExAC (Exome Aggregation Consortium)ENSG00000147082
GNOMAD BrowserENSG00000147082
Varsome BrowserCCNB3
Genetic variants : HAPMAP85417
Genomic Variants (DGV)CCNB3 [DGVbeta]
DECIPHERCCNB3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCCNB3 
Mutations
ICGC Data PortalCCNB3 
TCGA Data PortalCCNB3 
Broad Tumor PortalCCNB3
OASIS PortalCCNB3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCCNB3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCCNB3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch CCNB3
DgiDB (Drug Gene Interaction Database)CCNB3
DoCM (Curated mutations)CCNB3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CCNB3 (select a term)
intoGenCCNB3
Cancer3DCCNB3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300456   
Orphanet
DisGeNETCCNB3
MedgenCCNB3
Genetic Testing Registry CCNB3
NextProtQ8WWL7 [Medical]
TSGene85417
GENETestsCCNB3
Target ValidationCCNB3
Huge Navigator CCNB3 [HugePedia]
snp3D : Map Gene to Disease85417
BioCentury BCIQCCNB3
ClinGenCCNB3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD85417
Chemical/Pharm GKB GenePA38653
Clinical trialCCNB3
Miscellaneous
canSAR (ICR)CCNB3 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCCNB3
EVEXCCNB3
GoPubMedCCNB3
iHOPCCNB3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Aug 27 11:13:44 CEST 2018

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