CCNDBP1 (cyclin D1 binding protein 1)

2007-02-01  

Identity

HGNC
LOCATION
15q15.2
LOCUSID
ALIAS
DIP1,GCIP,HHM
FUSION GENES

Other Information

Locus ID:

NCBI: 23582
MIM: 607089
HGNC: 1587
Ensembl: ENSG00000166946

Variants:

dbSNP: 23582
ClinVar: 23582
TCGA: ENSG00000166946
COSMIC: CCNDBP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166946ENST00000300213O95273
ENSG00000166946ENST00000562553H3BQA6
ENSG00000166946ENST00000563065H3BQA6
ENSG00000166946ENST00000565296O95273
ENSG00000166946ENST00000566515O95273
ENSG00000166946ENST00000567434H3BUF4
ENSG00000166946ENST00000568507H3BR23
ENSG00000166946ENST00000569745H3BUF4

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
370584782023rs66651343 and rs12909095 confer lung cancer risk by regulating CCNDBP1 expression.0
370584782023rs66651343 and rs12909095 confer lung cancer risk by regulating CCNDBP1 expression.0
335764552021Grap2 cyclin D interacting protein negatively regulates CREB‑binding protein, inhibiting fibroblast‑like synoviocyte growth.2
335764552021Grap2 cyclin D interacting protein negatively regulates CREB‑binding protein, inhibiting fibroblast‑like synoviocyte growth.2
319079802020MEK2 is a critical modulating mechanism to down-regulate GCIP stability and function in cancer cells.6
319079802020MEK2 is a critical modulating mechanism to down-regulate GCIP stability and function in cancer cells.6
260029592015Maid is a negative regulator of transforming growth factor-β-induced cell migration.7
261071952015miR-9 Modulates Osteosarcoma Cell Growth by Targeting the GCIP Tumor Suppressor.15
260029592015Maid is a negative regulator of transforming growth factor-β-induced cell migration.7
261071952015miR-9 Modulates Osteosarcoma Cell Growth by Targeting the GCIP Tumor Suppressor.15
249708092014GCIP functions as a tumor suppressor in non-small cell lung cancer by suppressing Id1-mediated tumor promotion.7
249708092014GCIP functions as a tumor suppressor in non-small cell lung cancer by suppressing Id1-mediated tumor promotion.7
224533382012Structure of a dominant-negative helix-loop-helix transcriptional regulator suggests mechanisms of autoinhibition.14
224533382012Structure of a dominant-negative helix-loop-helix transcriptional regulator suggests mechanisms of autoinhibition.14
204605302010A novel senescence-evasion mechanism involving Grap2 and Cyclin D interacting protein inactivation by Ras associated with diabetes in cancer cells under doxorubicin treatment.14

Citation

Dessen P

CCNDBP1 (cyclin D1 binding protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45933/ccndbp1