Atlas of Genetics and Cytogenetics in Oncology and Haematology

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CCNE2 (cyclin E2)

Identity

Alias_symbol (synonym)CYCE2
Other alias
HGNC (Hugo) CCNE2
LocusID (NCBI) 9134
Atlas_Id 957
Location 8q22.1  [Link to chromosome band 8q22]
Location_base_pair Starts at 94880225 and ends at 94895254 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CCNE2 (8q22.1) / HSPH1 (13q12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CCNE2   1590
Cards
Entrez_Gene (NCBI)CCNE2  9134  cyclin E2
AliasesCYCE2
GeneCards (Weizmann)CCNE2
Ensembl hg19 (Hinxton)ENSG00000175305 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175305 [Gene_View]  ENSG00000175305 [Sequence]  chr8:94880225-94895254 [Contig_View]  CCNE2 [Vega]
ICGC DataPortalENSG00000175305
TCGA cBioPortalCCNE2
AceView (NCBI)CCNE2
Genatlas (Paris)CCNE2
WikiGenes9134
SOURCE (Princeton)CCNE2
Genetics Home Reference (NIH)CCNE2
Genomic and cartography
GoldenPath hg38 (UCSC)CCNE2  -     chr8:94880225-94895254 -  8q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CCNE2  -     8q22.1   [Description]    (hg19-Feb_2009)
EnsemblCCNE2 - 8q22.1 [CytoView hg19]  CCNE2 - 8q22.1 [CytoView hg38]
Mapping of homologs : NCBICCNE2 [Mapview hg19]  CCNE2 [Mapview hg38]
OMIM603775   
Gene and transcription
Genbank (Entrez)AA830205 AF091433 AF102778 AF106690 AF112857
RefSeq transcript (Entrez)NM_004702 NM_057735 NM_057749
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CCNE2
Cluster EST : UnigeneHs.521693 [ NCBI ]
CGAP (NCI)Hs.521693
Alternative Splicing GalleryENSG00000175305
Gene ExpressionCCNE2 [ NCBI-GEO ]   CCNE2 [ EBI - ARRAY_EXPRESS ]   CCNE2 [ SEEK ]   CCNE2 [ MEM ]
Gene Expression Viewer (FireBrowse)CCNE2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9134
GTEX Portal (Tissue expression)CCNE2
Human Protein AtlasENSG00000175305-CCNE2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO96020   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO96020  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO96020
Splice isoforms : SwissVarO96020
PhosPhoSitePlusO96020
Domaine pattern : Prosite (Expaxy)CYCLINS (PS00292)   
Domains : Interpro (EBI)Cyclin-like    Cyclin-like_sf    Cyclin_C-dom    Cyclin_E    Cyclin_N   
Domain families : Pfam (Sanger)Cyclin_C (PF02984)    Cyclin_N (PF00134)   
Domain families : Pfam (NCBI)pfam02984    pfam00134   
Domain families : Smart (EMBL)CYCLIN (SM00385)  Cyclin_C (SM01332)  
Conserved Domain (NCBI)CCNE2
DMDM Disease mutations9134
Blocks (Seattle)CCNE2
SuperfamilyO96020
Human Protein Atlas [tissue]ENSG00000175305-CCNE2 [tissue]
Peptide AtlasO96020
HPRD04801
IPIIPI00014085   IPI00219502   IPI00791397   IPI00791955   IPI00985208   IPI00794475   IPI00974365   
Protein Interaction databases
DIP (DOE-UCLA)O96020
IntAct (EBI)O96020
FunCoupENSG00000175305
BioGRIDCCNE2
STRING (EMBL)CCNE2
ZODIACCCNE2
Ontologies - Pathways
QuickGOO96020
Ontology : AmiGOregulation of cyclin-dependent protein serine/threonine kinase activity  G1/S transition of mitotic cell cycle  mitotic cell cycle  cyclin-dependent protein kinase holoenzyme complex  telomere maintenance  protein kinase activity  cyclin-dependent protein serine/threonine kinase activity  protein binding  nucleus  nucleoplasm  cytoplasm  centrosome  cytosol  DNA replication initiation  protein phosphorylation  regulation of mitotic nuclear division  synapsis  positive regulation of cell proliferation  cyclin-dependent protein serine/threonine kinase regulator activity  protein kinase binding  positive regulation of cell cycle  cell division  cyclin E2-CDK2 complex  cyclin E2-CDK2 complex  regulation of cellular protein localization  
Ontology : EGO-EBIregulation of cyclin-dependent protein serine/threonine kinase activity  G1/S transition of mitotic cell cycle  mitotic cell cycle  cyclin-dependent protein kinase holoenzyme complex  telomere maintenance  protein kinase activity  cyclin-dependent protein serine/threonine kinase activity  protein binding  nucleus  nucleoplasm  cytoplasm  centrosome  cytosol  DNA replication initiation  protein phosphorylation  regulation of mitotic nuclear division  synapsis  positive regulation of cell proliferation  cyclin-dependent protein serine/threonine kinase regulator activity  protein kinase binding  positive regulation of cell cycle  cell division  cyclin E2-CDK2 complex  cyclin E2-CDK2 complex  regulation of cellular protein localization  
Pathways : KEGGCell cycle    Oocyte meiosis    p53 signaling pathway    PI3K-Akt signaling pathway    Hepatitis B    Measles    Pathways in cancer    Viral carcinogenesis    MicroRNAs in cancer    Prostate cancer    Small cell lung cancer   
NDEx NetworkCCNE2
Atlas of Cancer Signalling NetworkCCNE2
Wikipedia pathwaysCCNE2
Orthology - Evolution
OrthoDB9134
GeneTree (enSembl)ENSG00000175305
Phylogenetic Trees/Animal Genes : TreeFamCCNE2
HOGENOMO96020
Homologs : HomoloGeneCCNE2
Homology/Alignments : Family Browser (UCSC)CCNE2
Gene fusions - Rearrangements
Fusion : QuiverCCNE2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCCNE2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CCNE2
dbVarCCNE2
ClinVarCCNE2
1000_GenomesCCNE2 
Exome Variant ServerCCNE2
ExAC (Exome Aggregation Consortium)ENSG00000175305
GNOMAD BrowserENSG00000175305
Varsome BrowserCCNE2
Genetic variants : HAPMAP9134
Genomic Variants (DGV)CCNE2 [DGVbeta]
DECIPHERCCNE2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCCNE2 
Mutations
ICGC Data PortalCCNE2 
TCGA Data PortalCCNE2 
Broad Tumor PortalCCNE2
OASIS PortalCCNE2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCCNE2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCCNE2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CCNE2
DgiDB (Drug Gene Interaction Database)CCNE2
DoCM (Curated mutations)CCNE2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CCNE2 (select a term)
intoGenCCNE2
Cancer3DCCNE2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603775   
Orphanet
DisGeNETCCNE2
MedgenCCNE2
Genetic Testing Registry CCNE2
NextProtO96020 [Medical]
TSGene9134
GENETestsCCNE2
Target ValidationCCNE2
Huge Navigator CCNE2 [HugePedia]
snp3D : Map Gene to Disease9134
BioCentury BCIQCCNE2
ClinGenCCNE2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9134
Chemical/Pharm GKB GenePA26155
Clinical trialCCNE2
Miscellaneous
canSAR (ICR)CCNE2 (select the gene name)
DataMed IndexCCNE2
Probes
Litterature
PubMed51 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCCNE2
EVEXCCNE2
GoPubMedCCNE2
iHOPCCNE2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Jan 17 18:05:02 CET 2019
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