Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CCNE2 (cyclin E2)

Identity

Alias (NCBI)CYCE2
HGNC (Hugo) CCNE2
HGNC Alias symbCYCE2
LocusID (NCBI) 9134
Atlas_Id 957
Location 8q22.1  [Link to chromosome band 8q22]
Location_base_pair Starts at 94880225 and ends at 94895254 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CCNE2 (8q22.1)::HSPH1 (13q12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)CCNE2   1590
Cards
Entrez_Gene (NCBI)CCNE2    cyclin E2
AliasesCYCE2
GeneCards (Weizmann)CCNE2
Ensembl hg19 (Hinxton)ENSG00000175305 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175305 [Gene_View]  ENSG00000175305 [Sequence]  chr8:94880225-94895254 [Contig_View]  CCNE2 [Vega]
ICGC DataPortalENSG00000175305
TCGA cBioPortalCCNE2
AceView (NCBI)CCNE2
Genatlas (Paris)CCNE2
SOURCE (Princeton)CCNE2
Genetics Home Reference (NIH)CCNE2
Genomic and cartography
GoldenPath hg38 (UCSC)CCNE2  -     chr8:94880225-94895254 -  8q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CCNE2  -     8q22.1   [Description]    (hg19-Feb_2009)
GoldenPathCCNE2 - 8q22.1 [CytoView hg19]  CCNE2 - 8q22.1 [CytoView hg38]
ImmunoBaseENSG00000175305
Genome Data Viewer NCBICCNE2 [Mapview hg19]  
OMIM603775   
Gene and transcription
Genbank (Entrez)AA830205 AF091433 AF102778 AF106690 AF112857
RefSeq transcript (Entrez)NM_004702 NM_057735 NM_057749
Consensus coding sequences : CCDS (NCBI)CCNE2
Gene ExpressionCCNE2 [ NCBI-GEO ]   CCNE2 [ EBI - ARRAY_EXPRESS ]   CCNE2 [ SEEK ]   CCNE2 [ MEM ]
Gene Expression Viewer (FireBrowse)CCNE2 [ Firebrowse - Broad ]
GenevisibleExpression of CCNE2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9134
GTEX Portal (Tissue expression)CCNE2
Human Protein AtlasENSG00000175305-CCNE2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO96020   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO96020  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO96020
PhosPhoSitePlusO96020
Domaine pattern : Prosite (Expaxy)CYCLINS (PS00292)   
Domains : Interpro (EBI)Cyclin    Cyclin-like    Cyclin-like_sf    Cyclin_C-dom    Cyclin_E    Cyclin_N   
Domain families : Pfam (Sanger)Cyclin_C (PF02984)    Cyclin_N (PF00134)   
Domain families : Pfam (NCBI)pfam02984    pfam00134   
Domain families : Smart (EMBL)CYCLIN (SM00385)  Cyclin_C (SM01332)  
Conserved Domain (NCBI)CCNE2
SuperfamilyO96020
AlphaFold pdb e-kbO96020   
Human Protein Atlas [tissue]ENSG00000175305-CCNE2 [tissue]
HPRD04801
Protein Interaction databases
DIP (DOE-UCLA)O96020
IntAct (EBI)O96020
BioGRIDCCNE2
STRING (EMBL)CCNE2
ZODIACCCNE2
Ontologies - Pathways
QuickGOO96020
Ontology : AmiGOregulation of cyclin-dependent protein serine/threonine kinase activity  G1/S transition of mitotic cell cycle  cyclin-dependent protein kinase holoenzyme complex  telomere maintenance  protein binding  nucleus  nucleoplasm  cytoplasm  centrosome  cytosol  DNA replication initiation  homologous chromosome pairing at meiosis  cyclin-dependent protein serine/threonine kinase regulator activity  protein kinase binding  regulation of protein localization  mitotic cell cycle phase transition  cell division  cyclin E1-CDK2 complex  cyclin E2-CDK2 complex  
Ontology : EGO-EBIregulation of cyclin-dependent protein serine/threonine kinase activity  G1/S transition of mitotic cell cycle  cyclin-dependent protein kinase holoenzyme complex  telomere maintenance  protein binding  nucleus  nucleoplasm  cytoplasm  centrosome  cytosol  DNA replication initiation  homologous chromosome pairing at meiosis  cyclin-dependent protein serine/threonine kinase regulator activity  protein kinase binding  regulation of protein localization  mitotic cell cycle phase transition  cell division  cyclin E1-CDK2 complex  cyclin E2-CDK2 complex  
Pathways : KEGGKEGG_CELL_CYCLE    KEGG_OOCYTE_MEIOSIS    KEGG_P53_SIGNALING    KEGG_PATHWAYS_IN_CANCER    KEGG_PROSTATE_CANCER    KEGG_SMALL_CELL_LUNG_CANCER   
NDEx NetworkCCNE2
Atlas of Cancer Signalling NetworkCCNE2
Wikipedia pathwaysCCNE2
Orthology - Evolution
OrthoDB9134
GeneTree (enSembl)ENSG00000175305
Phylogenetic Trees/Animal Genes : TreeFamCCNE2
Homologs : HomoloGeneCCNE2
Homology/Alignments : Family Browser (UCSC)CCNE2
Gene fusions - Rearrangements
Fusion : QuiverCCNE2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCCNE2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CCNE2
dbVarCCNE2
ClinVarCCNE2
MonarchCCNE2
1000_GenomesCCNE2 
Exome Variant ServerCCNE2
GNOMAD BrowserENSG00000175305
Varsome BrowserCCNE2
ACMGCCNE2 variants
VarityO96020
Genomic Variants (DGV)CCNE2 [DGVbeta]
DECIPHERCCNE2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCCNE2 
Mutations
ICGC Data PortalCCNE2 
TCGA Data PortalCCNE2 
Broad Tumor PortalCCNE2
OASIS PortalCCNE2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCCNE2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCCNE2
Mutations and Diseases : HGMDCCNE2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaCCNE2
DgiDB (Drug Gene Interaction Database)CCNE2
DoCM (Curated mutations)CCNE2
CIViC (Clinical Interpretations of Variants in Cancer)CCNE2
Cancer3DCCNE2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603775   
Orphanet
DisGeNETCCNE2
MedgenCCNE2
Genetic Testing Registry CCNE2
NextProtO96020 [Medical]
GENETestsCCNE2
Target ValidationCCNE2
Huge Navigator CCNE2 [HugePedia]
ClinGenCCNE2
Clinical trials, drugs, therapy
MyCancerGenomeCCNE2
Protein Interactions : CTDCCNE2
Pharm GKB GenePA26155
PharosO96020
Clinical trialCCNE2
Miscellaneous
canSAR (ICR)CCNE2
HarmonizomeCCNE2
ARCHS4CCNE2
DataMed IndexCCNE2
Probes
Litterature
PubMed69 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCCNE2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Jan 20 12:26:14 CET 2022

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