Identity
HGNC
LOCATION
16p13.3
LOCUSID
ALIAS
FBX1,FBXO1,FTDALS5
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 899
MIM: 600227
HGNC: 1591
Ensembl: ENSG00000162063
Variants:
dbSNP: 899
ClinVar: 899
TCGA: ENSG00000162063
COSMIC: CCNF
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000162063 | ENST00000293968 | H0Y2P7 |
| ENSG00000162063 | ENST00000397066 | P41002 |
| ENSG00000162063 | ENST00000564236 | H3BUD3 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36062310 | 2024 | Cyclin F, Neurodegeneration, and the Pathogenesis of ALS/FTD. | 3 |
| 38654021 | 2024 | Overexpression of cyclin F/CCNF as an independent prognostic factor for poor survival in clear cell renal cell carcinoma. | 0 |
| 36062310 | 2024 | Cyclin F, Neurodegeneration, and the Pathogenesis of ALS/FTD. | 3 |
| 38654021 | 2024 | Overexpression of cyclin F/CCNF as an independent prognostic factor for poor survival in clear cell renal cell carcinoma. | 0 |
| 36898988 | 2023 | The Skp1-Cullin1-FBXO1 complex is a pleiotropic regulator required for the formation of gametes and motile forms in Plasmodium berghei. | 8 |
| 37171577 | 2023 | Genetic and Phenotypic Spectrum of Amyotrophic Lateral Sclerosis Patients with CCNF Variants from a Large Chinese Cohort. | 0 |
| 37220877 | 2023 | ALS-linked CCNF variant disrupts motor neuron ubiquitin homeostasis. | 2 |
| 37243816 | 2023 | The E3 Ubiquitin Ligase SCF Cyclin F Promotes Sequestosome-1/p62 Insolubility and Foci Formation and is Dysregulated in ALS and FTD Pathogenesis. | 0 |
| 37993492 | 2023 | ALS/FTD-associated mutation in cyclin F inhibits ER-Golgi trafficking, inducing ER stress, ERAD and Golgi fragmentation. | 1 |
| 36898988 | 2023 | The Skp1-Cullin1-FBXO1 complex is a pleiotropic regulator required for the formation of gametes and motile forms in Plasmodium berghei. | 8 |
| 37171577 | 2023 | Genetic and Phenotypic Spectrum of Amyotrophic Lateral Sclerosis Patients with CCNF Variants from a Large Chinese Cohort. | 0 |
| 37220877 | 2023 | ALS-linked CCNF variant disrupts motor neuron ubiquitin homeostasis. | 2 |
| 37243816 | 2023 | The E3 Ubiquitin Ligase SCF Cyclin F Promotes Sequestosome-1/p62 Insolubility and Foci Formation and is Dysregulated in ALS and FTD Pathogenesis. | 0 |
| 37993492 | 2023 | ALS/FTD-associated mutation in cyclin F inhibits ER-Golgi trafficking, inducing ER stress, ERAD and Golgi fragmentation. | 1 |
| 36114006 | 2022 | ALS-linked loss of Cyclin-F function affects HSP90. | 3 |
Citation
Dessen P
CCNF (cyclin F)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/958/ccnf
