CCNL1 (cyclin L1)

2003-12-01  

Identity

HGNC
LOCATION
3q25.31
LOCUSID
ALIAS
ANIA6A,BM-001,PRO1073,ania-6a
FUSION GENES

Other Information

Locus ID:

NCBI: 57018
MIM: 613384
HGNC: 20569
Ensembl: ENSG00000163660

Variants:

dbSNP: 57018
ClinVar: 57018
TCGA: ENSG00000163660
COSMIC: CCNL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163660ENST00000295925Q9UK58
ENSG00000163660ENST00000295926Q9UK58
ENSG00000163660ENST00000461804Q9UK58
ENSG00000163660ENST00000465947Q9UK58
ENSG00000163660ENST00000468977H7C4G1
ENSG00000163660ENST00000470121Q9UK58
ENSG00000163660ENST00000475298Q9UK58
ENSG00000163660ENST00000477127Q9UK58
ENSG00000163660ENST00000631619Q9UK58

Expression (GTEx)

0
50
100
150
200

References

Pubmed IDYearTitleCitations
203721502010Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight.88
182160182008Characterization of cyclin L1 and L2 interactions with CDK11 and splicing factors: influence of cyclin L isoforms on splice site selection.45
119809062002Cyclin L is an RS domain protein involved in pre-mRNA splicing.31
119809062002Cyclin L is an RS domain protein involved in pre-mRNA splicing.31
157000362005Amplification of Cyclin L1 is associated with lymph node metastases in head and neck squamous cell carcinoma (HNSCC).9
215862742011A fine balance between CCNL1 and TIMP1 contributes to the development of breast cancer cells.9
174949912007Characterization of cyclin L1 as an immobile component of the splicing factor compartment.8
213071402011Variants near CCNL1/LEKR1 and in ADCY5 and fetal growth characteristics in different trimesters.7
220732612011The birth weight lowering C-allele of rs900400 near LEKR1 and CCNL1 associates with elevated insulin release following an oral glucose challenge.7
217129882011Absence of birth-weight lowering effect of ADCY5 and near CCNL, but association of impaired glucose-insulin homeostasis with ADCY5 in Asian Indians.6

Citation

Dessen P

CCNL1 (cyclin L1)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/963/ccnl1