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CCNL2 (cyclin L2)

Identity

Alias_namesCCNM
cyclin M
Alias_symbol (synonym)ania-6b
PCEE
SB138
HLA-ISO
CCNS
Other aliasANIA-6B
HCLA-ISO
HGNC (Hugo) CCNL2
LocusID (NCBI) 81669
Atlas_Id 56362
Location 1p36.33  [Link to chromosome band 1p36]
Location_base_pair Starts at 1392288 and ends at 1399342 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CCNL2 (1p36.33) / UBA2 (19q13.11)SMA4 (5q13.2) / CCNL2 (1p36.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CCNL2   20570
Cards
Entrez_Gene (NCBI)CCNL2  81669  cyclin L2
AliasesANIA-6B; CCNM; CCNS; HCLA-ISO; 
HLA-ISO; PCEE; SB138
GeneCards (Weizmann)CCNL2
Ensembl hg19 (Hinxton)ENSG00000221978 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000221978 [Gene_View]  chr1:1392288-1399342 [Contig_View]  CCNL2 [Vega]
ICGC DataPortalENSG00000221978
TCGA cBioPortalCCNL2
AceView (NCBI)CCNL2
Genatlas (Paris)CCNL2
WikiGenes81669
SOURCE (Princeton)CCNL2
Genetics Home Reference (NIH)CCNL2
Genomic and cartography
GoldenPath hg38 (UCSC)CCNL2  -     chr1:1392288-1399342 -  1p36.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CCNL2  -     1p36.33   [Description]    (hg19-Feb_2009)
EnsemblCCNL2 - 1p36.33 [CytoView hg19]  CCNL2 - 1p36.33 [CytoView hg38]
Mapping of homologs : NCBICCNL2 [Mapview hg19]  CCNL2 [Mapview hg38]
OMIM613482   
Gene and transcription
Genbank (Entrez)AF087903 AF251294 AK000685 AK026796 AK027770
RefSeq transcript (Entrez)NM_001039577 NM_001144867 NM_001144868 NM_001320153 NM_001320155 NM_001350497 NM_001350498 NM_001350499 NM_001350500 NM_030937
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CCNL2
Cluster EST : UnigeneHs.515704 [ NCBI ]
CGAP (NCI)Hs.515704
Alternative Splicing GalleryENSG00000221978
Gene ExpressionCCNL2 [ NCBI-GEO ]   CCNL2 [ EBI - ARRAY_EXPRESS ]   CCNL2 [ SEEK ]   CCNL2 [ MEM ]
Gene Expression Viewer (FireBrowse)CCNL2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)81669
GTEX Portal (Tissue expression)CCNL2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96S94   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96S94  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96S94
Splice isoforms : SwissVarQ96S94
PhosPhoSitePlusQ96S94
Domains : Interpro (EBI)Cyclin-like    Cyclin_C-dom    Cyclin_L/T    Cyclin_N   
Domain families : Pfam (Sanger)Cyclin_C (PF02984)    Cyclin_N (PF00134)   
Domain families : Pfam (NCBI)pfam02984    pfam00134   
Domain families : Smart (EMBL)CYCLIN (SM00385)  Cyclin_C (SM01332)  
Conserved Domain (NCBI)CCNL2
DMDM Disease mutations81669
Blocks (Seattle)CCNL2
SuperfamilyQ96S94
Human Protein AtlasENSG00000221978
Peptide AtlasQ96S94
HPRD10815
IPIIPI00066458   IPI00478642   IPI00787908   IPI00909844   IPI00844179   IPI00941687   IPI00921515   IPI00967708   
Protein Interaction databases
DIP (DOE-UCLA)Q96S94
IntAct (EBI)Q96S94
FunCoupENSG00000221978
BioGRIDCCNL2
STRING (EMBL)CCNL2
ZODIACCCNL2
Ontologies - Pathways
QuickGOQ96S94
Ontology : AmiGOcyclin-dependent protein kinase holoenzyme complex  protein binding  nucleus  nucleoplasm  transcription, DNA-templated  cyclin-dependent protein serine/threonine kinase regulator activity  nuclear speck  protein kinase binding  intracellular membrane-bounded organelle  positive regulation of cyclin-dependent protein serine/threonine kinase activity  positive regulation of transcription from RNA polymerase II promoter  positive regulation of phosphorylation of RNA polymerase II C-terminal domain  
Ontology : EGO-EBIcyclin-dependent protein kinase holoenzyme complex  protein binding  nucleus  nucleoplasm  transcription, DNA-templated  cyclin-dependent protein serine/threonine kinase regulator activity  nuclear speck  protein kinase binding  intracellular membrane-bounded organelle  positive regulation of cyclin-dependent protein serine/threonine kinase activity  positive regulation of transcription from RNA polymerase II promoter  positive regulation of phosphorylation of RNA polymerase II C-terminal domain  
NDEx NetworkCCNL2
Atlas of Cancer Signalling NetworkCCNL2
Wikipedia pathwaysCCNL2
Orthology - Evolution
OrthoDB81669
GeneTree (enSembl)ENSG00000221978
Phylogenetic Trees/Animal Genes : TreeFamCCNL2
HOVERGENQ96S94
HOGENOMQ96S94
Homologs : HomoloGeneCCNL2
Homology/Alignments : Family Browser (UCSC)CCNL2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCCNL2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CCNL2
dbVarCCNL2
ClinVarCCNL2
1000_GenomesCCNL2 
Exome Variant ServerCCNL2
ExAC (Exome Aggregation Consortium)CCNL2 (select the gene name)
Genetic variants : HAPMAP81669
Genomic Variants (DGV)CCNL2 [DGVbeta]
DECIPHERCCNL2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCCNL2 
Mutations
ICGC Data PortalCCNL2 
TCGA Data PortalCCNL2 
Broad Tumor PortalCCNL2
OASIS PortalCCNL2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCCNL2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCCNL2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CCNL2
DgiDB (Drug Gene Interaction Database)CCNL2
DoCM (Curated mutations)CCNL2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CCNL2 (select a term)
intoGenCCNL2
Cancer3DCCNL2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613482   
Orphanet
MedgenCCNL2
Genetic Testing Registry CCNL2
NextProtQ96S94 [Medical]
TSGene81669
GENETestsCCNL2
Huge Navigator CCNL2 [HugePedia]
snp3D : Map Gene to Disease81669
BioCentury BCIQCCNL2
ClinGenCCNL2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD81669
Chemical/Pharm GKB GenePA134973681
Clinical trialCCNL2
Miscellaneous
canSAR (ICR)CCNL2 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCCNL2
EVEXCCNL2
GoPubMedCCNL2
iHOPCCNL2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:09:25 CEST 2017

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