Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CCNT1 (cyclin T1)

Identity

Alias_namesHIVE1
human immunodeficiency virus type 1 (HIV-1) expression (elevated) 1
Alias_symbol (synonym)CCNT
CYCT1
Other alias
HGNC (Hugo) CCNT1
LocusID (NCBI) 904
Atlas_Id 47404
Location 12q13.11  [Link to chromosome band 12q13]
Location_base_pair Starts at 48688458 and ends at 48716998 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(4;11)(q21;q23) KMT2A/AFF1


External links

Nomenclature
HGNC (Hugo)CCNT1   1599
Cards
Entrez_Gene (NCBI)CCNT1  904  cyclin T1
AliasesCCNT; CYCT1; HIVE1
GeneCards (Weizmann)CCNT1
Ensembl hg19 (Hinxton)ENSG00000129315 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000129315 [Gene_View]  chr12:48688458-48716998 [Contig_View]  CCNT1 [Vega]
ICGC DataPortalENSG00000129315
TCGA cBioPortalCCNT1
AceView (NCBI)CCNT1
Genatlas (Paris)CCNT1
WikiGenes904
SOURCE (Princeton)CCNT1
Genetics Home Reference (NIH)CCNT1
Genomic and cartography
GoldenPath hg38 (UCSC)CCNT1  -     chr12:48688458-48716998 -  12q13.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CCNT1  -     12q13.11   [Description]    (hg19-Feb_2009)
EnsemblCCNT1 - 12q13.11 [CytoView hg19]  CCNT1 - 12q13.11 [CytoView hg38]
Mapping of homologs : NCBICCNT1 [Mapview hg19]  CCNT1 [Mapview hg38]
OMIM143055   
Gene and transcription
Genbank (Entrez)AF045161 AF048730 AK002085 AK290990 AL832083
RefSeq transcript (Entrez)NM_001240 NM_001277842
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CCNT1
Cluster EST : UnigeneHs.92308 [ NCBI ]
CGAP (NCI)Hs.92308
Alternative Splicing GalleryENSG00000129315
Gene ExpressionCCNT1 [ NCBI-GEO ]   CCNT1 [ EBI - ARRAY_EXPRESS ]   CCNT1 [ SEEK ]   CCNT1 [ MEM ]
Gene Expression Viewer (FireBrowse)CCNT1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)904
GTEX Portal (Tissue expression)CCNT1
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60563   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60563  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60563
Splice isoforms : SwissVarO60563
PhosPhoSitePlusO60563
Domains : Interpro (EBI)CCNT1    Cyclin-like    Cyclin_N   
Domain families : Pfam (Sanger)Cyclin_N (PF00134)   
Domain families : Pfam (NCBI)pfam00134   
Domain families : Smart (EMBL)CYCLIN (SM00385)  
Conserved Domain (NCBI)CCNT1
DMDM Disease mutations904
Blocks (Seattle)CCNT1
PDB (SRS)2PK2    3BLH    3BLQ    3BLR    3LQ5    3MI9    3MIA    3MY1    3TN8    3TNH    3TNI    4BCF    4BCG    4BCH    4BCI    4BCJ    4EC8    4EC9    4IMY    4OGR    4OR5    5L1Z   
PDB (PDBSum)2PK2    3BLH    3BLQ    3BLR    3LQ5    3MI9    3MIA    3MY1    3TN8    3TNH    3TNI    4BCF    4BCG    4BCH    4BCI    4BCJ    4EC8    4EC9    4IMY    4OGR    4OR5    5L1Z   
PDB (IMB)2PK2    3BLH    3BLQ    3BLR    3LQ5    3MI9    3MIA    3MY1    3TN8    3TNH    3TNI    4BCF    4BCG    4BCH    4BCI    4BCJ    4EC8    4EC9    4IMY    4OGR    4OR5    5L1Z   
PDB (RSDB)2PK2    3BLH    3BLQ    3BLR    3LQ5    3MI9    3MIA    3MY1    3TN8    3TNH    3TNI    4BCF    4BCG    4BCH    4BCI    4BCJ    4EC8    4EC9    4IMY    4OGR    4OR5    5L1Z   
Structural Biology KnowledgeBase2PK2    3BLH    3BLQ    3BLR    3LQ5    3MI9    3MIA    3MY1    3TN8    3TNH    3TNI    4BCF    4BCG    4BCH    4BCI    4BCJ    4EC8    4EC9    4IMY    4OGR    4OR5    5L1Z   
SCOP (Structural Classification of Proteins)2PK2    3BLH    3BLQ    3BLR    3LQ5    3MI9    3MIA    3MY1    3TN8    3TNH    3TNI    4BCF    4BCG    4BCH    4BCI    4BCJ    4EC8    4EC9    4IMY    4OGR    4OR5    5L1Z   
CATH (Classification of proteins structures)2PK2    3BLH    3BLQ    3BLR    3LQ5    3MI9    3MIA    3MY1    3TN8    3TNH    3TNI    4BCF    4BCG    4BCH    4BCI    4BCJ    4EC8    4EC9    4IMY    4OGR    4OR5    5L1Z   
SuperfamilyO60563
Human Protein AtlasENSG00000129315
Peptide AtlasO60563
HPRD03938
IPIIPI00030247   IPI00791037   
Protein Interaction databases
DIP (DOE-UCLA)O60563
IntAct (EBI)O60563
FunCoupENSG00000129315
BioGRIDCCNT1
STRING (EMBL)CCNT1
ZODIACCCNT1
Ontologies - Pathways
QuickGOO60563
Ontology : AmiGOregulation of cyclin-dependent protein serine/threonine kinase activity  DNA binding  chromatin binding  protein serine/threonine kinase activity  protein binding  nucleus  nucleoplasm  nucleoplasm  nucleolus  transcription from RNA polymerase II promoter  transcription elongation from RNA polymerase II promoter  protein phosphorylation  cell cycle  cyclin/CDK positive transcription elongation factor complex  transcription factor binding  viral process  cyclin-dependent protein serine/threonine kinase regulator activity  protein kinase binding  snRNA transcription from RNA polymerase II promoter  positive regulation by host of viral transcription  transcription regulatory region DNA binding  positive regulation of cyclin-dependent protein serine/threonine kinase activity  positive regulation of transcription from RNA polymerase II promoter  positive regulation of transcription from RNA polymerase II promoter  positive regulation of viral transcription  cell division  RNA polymerase binding  7SK snRNA binding  negative regulation of mRNA polyadenylation  positive regulation of phosphorylation of RNA polymerase II C-terminal domain  
Ontology : EGO-EBIregulation of cyclin-dependent protein serine/threonine kinase activity  DNA binding  chromatin binding  protein serine/threonine kinase activity  protein binding  nucleus  nucleoplasm  nucleoplasm  nucleolus  transcription from RNA polymerase II promoter  transcription elongation from RNA polymerase II promoter  protein phosphorylation  cell cycle  cyclin/CDK positive transcription elongation factor complex  transcription factor binding  viral process  cyclin-dependent protein serine/threonine kinase regulator activity  protein kinase binding  snRNA transcription from RNA polymerase II promoter  positive regulation by host of viral transcription  transcription regulatory region DNA binding  positive regulation of cyclin-dependent protein serine/threonine kinase activity  positive regulation of transcription from RNA polymerase II promoter  positive regulation of transcription from RNA polymerase II promoter  positive regulation of viral transcription  cell division  RNA polymerase binding  7SK snRNA binding  negative regulation of mRNA polyadenylation  positive regulation of phosphorylation of RNA polymerase II C-terminal domain  
Pathways : KEGGTranscriptional misregulation in cancer   
NDEx NetworkCCNT1
Atlas of Cancer Signalling NetworkCCNT1
Wikipedia pathwaysCCNT1
Orthology - Evolution
OrthoDB904
GeneTree (enSembl)ENSG00000129315
Phylogenetic Trees/Animal Genes : TreeFamCCNT1
HOVERGENO60563
HOGENOMO60563
Homologs : HomoloGeneCCNT1
Homology/Alignments : Family Browser (UCSC)CCNT1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCCNT1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CCNT1
dbVarCCNT1
ClinVarCCNT1
1000_GenomesCCNT1 
Exome Variant ServerCCNT1
ExAC (Exome Aggregation Consortium)CCNT1 (select the gene name)
Genetic variants : HAPMAP904
Genomic Variants (DGV)CCNT1 [DGVbeta]
DECIPHERCCNT1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCCNT1 
Mutations
ICGC Data PortalCCNT1 
TCGA Data PortalCCNT1 
Broad Tumor PortalCCNT1
OASIS PortalCCNT1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCCNT1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCCNT1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CCNT1
DgiDB (Drug Gene Interaction Database)CCNT1
DoCM (Curated mutations)CCNT1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CCNT1 (select a term)
intoGenCCNT1
Cancer3DCCNT1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM143055   
Orphanet
MedgenCCNT1
Genetic Testing Registry CCNT1
NextProtO60563 [Medical]
TSGene904
GENETestsCCNT1
Target ValidationCCNT1
Huge Navigator CCNT1 [HugePedia]
snp3D : Map Gene to Disease904
BioCentury BCIQCCNT1
ClinGenCCNT1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD904
Chemical/Pharm GKB GenePA26163
Clinical trialCCNT1
Miscellaneous
canSAR (ICR)CCNT1 (select the gene name)
Probes
Litterature
PubMed317 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCCNT1
EVEXCCNT1
GoPubMedCCNT1
iHOPCCNT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 13:49:05 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.