Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CCNT2 (cyclin T2)

Identity

Other aliasCYCT2
HGNC (Hugo) CCNT2
LocusID (NCBI) 905
Atlas_Id 43195
Location 2q21.3  [Link to chromosome band 2q21]
Location_base_pair Starts at 135676392 and ends at 135716915 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CCNT2 (2q21.3) / MAP3K19 (2q21.3)CCNT2 (2q21.3) / MTUS1 (8p22)NBAS (2p24.3) / CCNT2 (2q21.3)
RAB3GAP1 (2q21.3) / CCNT2 (2q21.3)CCNT2 2q21.3 YSK4RAB3GAP1 2q21.3 / CCNT2 2q21.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CCNT2   1600
Cards
Entrez_Gene (NCBI)CCNT2  905  cyclin T2
AliasesCYCT2
GeneCards (Weizmann)CCNT2
Ensembl hg19 (Hinxton)ENSG00000082258 [Gene_View]  chr2:135676392-135716915 [Contig_View]  CCNT2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000082258 [Gene_View]  chr2:135676392-135716915 [Contig_View]  CCNT2 [Vega]
ICGC DataPortalENSG00000082258
TCGA cBioPortalCCNT2
AceView (NCBI)CCNT2
Genatlas (Paris)CCNT2
WikiGenes905
SOURCE (Princeton)CCNT2
Genetics Home Reference (NIH)CCNT2
Genomic and cartography
GoldenPath hg19 (UCSC)CCNT2  -     chr2:135676392-135716915 +  2q21.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CCNT2  -     2q21.3   [Description]    (hg38-Dec_2013)
EnsemblCCNT2 - 2q21.3 [CytoView hg19]  CCNT2 - 2q21.3 [CytoView hg38]
Mapping of homologs : NCBICCNT2 [Mapview hg19]  CCNT2 [Mapview hg38]
OMIM603862   
Gene and transcription
Genbank (Entrez)AF048731 AF048732 AK023645 AK075041 AK292913
RefSeq transcript (Entrez)NM_001241 NM_001320748 NM_001320749 NM_058241
RefSeq genomic (Entrez)NC_000002 NC_018913 NG_029189 NT_005403 NW_004929304
Consensus coding sequences : CCDS (NCBI)CCNT2
Cluster EST : UnigeneHs.744115 [ NCBI ]
CGAP (NCI)Hs.744115
Alternative Splicing GalleryENSG00000082258
Gene ExpressionCCNT2 [ NCBI-GEO ]   CCNT2 [ EBI - ARRAY_EXPRESS ]   CCNT2 [ SEEK ]   CCNT2 [ MEM ]
Gene Expression Viewer (FireBrowse)CCNT2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)905
GTEX Portal (Tissue expression)CCNT2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60583   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60583  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60583
Splice isoforms : SwissVarO60583
PhosPhoSitePlusO60583
Domains : Interpro (EBI)CCNT2    Cyclin-like    Cyclin_N   
Domain families : Pfam (Sanger)Cyclin_N (PF00134)   
Domain families : Pfam (NCBI)pfam00134   
Domain families : Smart (EMBL)CYCLIN (SM00385)  
Conserved Domain (NCBI)CCNT2
DMDM Disease mutations905
Blocks (Seattle)CCNT2
PDB (SRS)2IVX   
PDB (PDBSum)2IVX   
PDB (IMB)2IVX   
PDB (RSDB)2IVX   
Structural Biology KnowledgeBase2IVX   
SCOP (Structural Classification of Proteins)2IVX   
CATH (Classification of proteins structures)2IVX   
SuperfamilyO60583
Human Protein AtlasENSG00000082258
Peptide AtlasO60583
HPRD04839
IPIIPI00030313   IPI00217564   IPI01013780   IPI00927944   IPI00926773   IPI00926372   IPI00925381   IPI00925629   
Protein Interaction databases
DIP (DOE-UCLA)O60583
IntAct (EBI)O60583
FunCoupENSG00000082258
BioGRIDCCNT2
STRING (EMBL)CCNT2
ZODIACCCNT2
Ontologies - Pathways
QuickGOO60583
Ontology : AmiGOregulation of cyclin-dependent protein serine/threonine kinase activity  cyclin-dependent protein kinase holoenzyme complex  transcription coactivator binding  chromatin binding  protein serine/threonine kinase activity  protein binding  nucleus  nucleoplasm  transcription from RNA polymerase II promoter  transcription elongation from RNA polymerase II promoter  protein phosphorylation  cell cycle  positive transcription elongation factor complex b  cyclin-dependent protein serine/threonine kinase regulator activity  early viral transcription  late viral transcription  protein kinase binding  snRNA transcription from RNA polymerase II promoter  positive regulation of cyclin-dependent protein serine/threonine kinase activity  positive regulation of transcription from RNA polymerase II promoter  positive regulation of transcription from RNA polymerase II promoter  perinuclear region of cytoplasm  regulation of muscle cell differentiation  cell division  RNA polymerase binding  7SK snRNA binding  positive regulation of phosphorylation of RNA polymerase II C-terminal domain  
Ontology : EGO-EBIregulation of cyclin-dependent protein serine/threonine kinase activity  cyclin-dependent protein kinase holoenzyme complex  transcription coactivator binding  chromatin binding  protein serine/threonine kinase activity  protein binding  nucleus  nucleoplasm  transcription from RNA polymerase II promoter  transcription elongation from RNA polymerase II promoter  protein phosphorylation  cell cycle  positive transcription elongation factor complex b  cyclin-dependent protein serine/threonine kinase regulator activity  early viral transcription  late viral transcription  protein kinase binding  snRNA transcription from RNA polymerase II promoter  positive regulation of cyclin-dependent protein serine/threonine kinase activity  positive regulation of transcription from RNA polymerase II promoter  positive regulation of transcription from RNA polymerase II promoter  perinuclear region of cytoplasm  regulation of muscle cell differentiation  cell division  RNA polymerase binding  7SK snRNA binding  positive regulation of phosphorylation of RNA polymerase II C-terminal domain  
Pathways : KEGGTranscriptional misregulation in cancer   
NDEx NetworkCCNT2
Atlas of Cancer Signalling NetworkCCNT2
Wikipedia pathwaysCCNT2
Orthology - Evolution
OrthoDB905
GeneTree (enSembl)ENSG00000082258
Phylogenetic Trees/Animal Genes : TreeFamCCNT2
HOVERGENO60583
HOGENOMO60583
Homologs : HomoloGeneCCNT2
Homology/Alignments : Family Browser (UCSC)CCNT2
Gene fusions - Rearrangements
Fusion : MitelmanCCNT2/MAP3K19 [2q21.3/2q21.3]  
Fusion : MitelmanNBAS/CCNT2 [2p24.3/2q21.3]  [t(2;2)(p24;q21)]  
Fusion : MitelmanRAB3GAP1/CCNT2 [2q21.3/2q21.3]  [t(2;2)(q21;q21)]  
Fusion: TCGACCNT2 2q21.3 YSK4 KIRC
Fusion: TCGARAB3GAP1 2q21.3 CCNT2 2q21.3 LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCCNT2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CCNT2
dbVarCCNT2
ClinVarCCNT2
1000_GenomesCCNT2 
Exome Variant ServerCCNT2
ExAC (Exome Aggregation Consortium)CCNT2 (select the gene name)
Genetic variants : HAPMAP905
Genomic Variants (DGV)CCNT2 [DGVbeta]
DECIPHER (Syndromes)2:135676392-135716915  ENSG00000082258
CONAN: Copy Number AnalysisCCNT2 
Mutations
ICGC Data PortalCCNT2 
TCGA Data PortalCCNT2 
Broad Tumor PortalCCNT2
OASIS PortalCCNT2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCCNT2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCCNT2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CCNT2
DgiDB (Drug Gene Interaction Database)CCNT2
DoCM (Curated mutations)CCNT2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CCNT2 (select a term)
intoGenCCNT2
Cancer3DCCNT2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603862   
Orphanet
MedgenCCNT2
Genetic Testing Registry CCNT2
NextProtO60583 [Medical]
TSGene905
GENETestsCCNT2
Huge Navigator CCNT2 [HugePedia]
snp3D : Map Gene to Disease905
BioCentury BCIQCCNT2
ClinGenCCNT2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD905
Chemical/Pharm GKB GenePA26164
Clinical trialCCNT2
Miscellaneous
canSAR (ICR)CCNT2 (select the gene name)
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCCNT2
EVEXCCNT2
GoPubMedCCNT2
iHOPCCNT2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 14:55:29 CEST 2017

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