Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CCNT2 (cyclin T2)

Identity

Alias (NCBI)CYCT2
HGNC (Hugo) CCNT2
LocusID (NCBI) 905
Atlas_Id 43195
Location 2q21.3  [Link to chromosome band 2q21]
Location_base_pair Starts at 134918822 and ends at 134959341 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CCNT2 (2q21.3) / MAP3K19 (2q21.3)CCNT2 (2q21.3) / MTUS1 (8p22)NBAS (2p24.3) / CCNT2 (2q21.3)
RAB3GAP1 (2q21.3) / CCNT2 (2q21.3)CCNT2 2q21.3 YSK4RAB3GAP1 2q21.3 / CCNT2 2q21.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)CCNT2   1600
Cards
Entrez_Gene (NCBI)CCNT2    cyclin T2
AliasesCYCT2
GeneCards (Weizmann)CCNT2
Ensembl hg19 (Hinxton)ENSG00000082258 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000082258 [Gene_View]  ENSG00000082258 [Sequence]  chr2:134918822-134959341 [Contig_View]  CCNT2 [Vega]
ICGC DataPortalENSG00000082258
TCGA cBioPortalCCNT2
AceView (NCBI)CCNT2
Genatlas (Paris)CCNT2
SOURCE (Princeton)CCNT2
Genetics Home Reference (NIH)CCNT2
Genomic and cartography
GoldenPath hg38 (UCSC)CCNT2  -     chr2:134918822-134959341 +  2q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CCNT2  -     2q21.3   [Description]    (hg19-Feb_2009)
GoldenPathCCNT2 - 2q21.3 [CytoView hg19]  CCNT2 - 2q21.3 [CytoView hg38]
ImmunoBaseENSG00000082258
Genome Data Viewer NCBICCNT2 [Mapview hg19]  
OMIM603862   
Gene and transcription
Genbank (Entrez)AF048731 AF048732 AK023645 AK075041 AK292913
RefSeq transcript (Entrez)NM_001241 NM_001320748 NM_001320749 NM_058241
Consensus coding sequences : CCDS (NCBI)CCNT2
Gene ExpressionCCNT2 [ NCBI-GEO ]   CCNT2 [ EBI - ARRAY_EXPRESS ]   CCNT2 [ SEEK ]   CCNT2 [ MEM ]
Gene Expression Viewer (FireBrowse)CCNT2 [ Firebrowse - Broad ]
GenevisibleExpression of CCNT2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)905
GTEX Portal (Tissue expression)CCNT2
Human Protein AtlasENSG00000082258-CCNT2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60583   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60583  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60583
PhosPhoSitePlusO60583
Domains : Interpro (EBI)CCNT2    Cyclin-like    Cyclin-like_sf    Cyclin/Ssn8    Cyclin_N   
Domain families : Pfam (Sanger)Cyclin_N (PF00134)   
Domain families : Pfam (NCBI)pfam00134   
Domain families : Smart (EMBL)CYCLIN (SM00385)  
Conserved Domain (NCBI)CCNT2
PDB (RSDB)2IVX   
PDB Europe2IVX   
PDB (PDBSum)2IVX   
PDB (IMB)2IVX   
Structural Biology KnowledgeBase2IVX   
SCOP (Structural Classification of Proteins)2IVX   
CATH (Classification of proteins structures)2IVX   
SuperfamilyO60583
AlphaFold pdb e-kbO60583   
Human Protein Atlas [tissue]ENSG00000082258-CCNT2 [tissue]
HPRD04839
Protein Interaction databases
DIP (DOE-UCLA)O60583
IntAct (EBI)O60583
BioGRIDCCNT2
STRING (EMBL)CCNT2
ZODIACCCNT2
Ontologies - Pathways
QuickGOO60583
Ontology : AmiGOregulation of cyclin-dependent protein serine/threonine kinase activity  transcription coactivator binding  chromatin binding  protein binding  nucleus  nucleus  nucleoplasm  nucleoplasm  cytosol  plasma membrane  regulation of transcription by RNA polymerase II  transcription by RNA polymerase II  transcription elongation from RNA polymerase II promoter  cell cycle  skeletal muscle tissue development  cyclin/CDK positive transcription elongation factor complex  cyclin/CDK positive transcription elongation factor complex  cyclin-dependent protein serine/threonine kinase regulator activity  early viral transcription  late viral transcription  positive regulation of DNA-templated transcription, elongation  snRNA transcription by RNA polymerase II  positive regulation of cyclin-dependent protein serine/threonine kinase activity  positive regulation of transcription by RNA polymerase II  positive regulation of transcription by RNA polymerase II  perinuclear region of cytoplasm  cell division  cyclin-dependent protein serine/threonine kinase activator activity  RNA polymerase binding  7SK snRNA binding  
Ontology : EGO-EBIregulation of cyclin-dependent protein serine/threonine kinase activity  transcription coactivator binding  chromatin binding  protein binding  nucleus  nucleus  nucleoplasm  nucleoplasm  cytosol  plasma membrane  regulation of transcription by RNA polymerase II  transcription by RNA polymerase II  transcription elongation from RNA polymerase II promoter  cell cycle  skeletal muscle tissue development  cyclin/CDK positive transcription elongation factor complex  cyclin/CDK positive transcription elongation factor complex  cyclin-dependent protein serine/threonine kinase regulator activity  early viral transcription  late viral transcription  positive regulation of DNA-templated transcription, elongation  snRNA transcription by RNA polymerase II  positive regulation of cyclin-dependent protein serine/threonine kinase activity  positive regulation of transcription by RNA polymerase II  positive regulation of transcription by RNA polymerase II  perinuclear region of cytoplasm  cell division  cyclin-dependent protein serine/threonine kinase activator activity  RNA polymerase binding  7SK snRNA binding  
Pathways : KEGGTranscriptional misregulation in cancer   
NDEx NetworkCCNT2
Atlas of Cancer Signalling NetworkCCNT2
Wikipedia pathwaysCCNT2
Orthology - Evolution
OrthoDB905
GeneTree (enSembl)ENSG00000082258
Phylogenetic Trees/Animal Genes : TreeFamCCNT2
Homologs : HomoloGeneCCNT2
Homology/Alignments : Family Browser (UCSC)CCNT2
Gene fusions - Rearrangements
Fusion : MitelmanCCNT2/MAP3K19 [2q21.3/2q21.3]  
Fusion : MitelmanNBAS/CCNT2 [2p24.3/2q21.3]  
Fusion : MitelmanRAB3GAP1/CCNT2 [2q21.3/2q21.3]  
Fusion : QuiverCCNT2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCCNT2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CCNT2
dbVarCCNT2
ClinVarCCNT2
MonarchCCNT2
1000_GenomesCCNT2 
Exome Variant ServerCCNT2
GNOMAD BrowserENSG00000082258
Varsome BrowserCCNT2
ACMGCCNT2 variants
VarityO60583
Genomic Variants (DGV)CCNT2 [DGVbeta]
DECIPHERCCNT2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCCNT2 
Mutations
ICGC Data PortalCCNT2 
TCGA Data PortalCCNT2 
Broad Tumor PortalCCNT2
OASIS PortalCCNT2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCCNT2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCCNT2
Mutations and Diseases : HGMDCCNT2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaCCNT2
DgiDB (Drug Gene Interaction Database)CCNT2
DoCM (Curated mutations)CCNT2
CIViC (Clinical Interpretations of Variants in Cancer)CCNT2
Cancer3DCCNT2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603862   
Orphanet
DisGeNETCCNT2
MedgenCCNT2
Genetic Testing Registry CCNT2
NextProtO60583 [Medical]
GENETestsCCNT2
Target ValidationCCNT2
Huge Navigator CCNT2 [HugePedia]
ClinGenCCNT2
Clinical trials, drugs, therapy
MyCancerGenomeCCNT2
Protein Interactions : CTDCCNT2
Pharm GKB GenePA26164
PharosO60583
Clinical trialCCNT2
Miscellaneous
canSAR (ICR)CCNT2
HarmonizomeCCNT2
DataMed IndexCCNT2
Probes
Litterature
PubMed55 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCCNT2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:02:48 CEST 2021

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