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CCR3 (C-C motif chemokine receptor 3)

Identity

Alias_namesCMKBR3
chemokine (C-C motif) receptor 3
Alias_symbol (synonym)CC-CKR-3
CKR3
CD193
Other alias
HGNC (Hugo) CCR3
LocusID (NCBI) 1232
Atlas_Id 46317
Location 3p21.31  [Link to chromosome band 3p21]
Location_base_pair Starts at 46242381 and ends at 46266706 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CCR3   1604
Cards
Entrez_Gene (NCBI)CCR3  1232  C-C motif chemokine receptor 3
AliasesCC-CKR-3; CD193; CKR3; CMKBR3
GeneCards (Weizmann)CCR3
Ensembl hg19 (Hinxton)ENSG00000183625 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000183625 [Gene_View]  chr3:46242381-46266706 [Contig_View]  CCR3 [Vega]
ICGC DataPortalENSG00000183625
TCGA cBioPortalCCR3
AceView (NCBI)CCR3
Genatlas (Paris)CCR3
WikiGenes1232
SOURCE (Princeton)CCR3
Genetics Home Reference (NIH)CCR3
Genomic and cartography
GoldenPath hg38 (UCSC)CCR3  -     chr3:46242381-46266706 +  3p21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CCR3  -     3p21.31   [Description]    (hg19-Feb_2009)
EnsemblCCR3 - 3p21.31 [CytoView hg19]  CCR3 - 3p21.31 [CytoView hg38]
Mapping of homologs : NCBICCR3 [Mapview hg19]  CCR3 [Mapview hg38]
OMIM601268   
Gene and transcription
Genbank (Entrez)AF026535 AF224495 AF262299 AF262300 AF262301
RefSeq transcript (Entrez)NM_001164680 NM_001837 NM_178328 NM_178329
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CCR3
Cluster EST : UnigeneHs.506190 [ NCBI ]
CGAP (NCI)Hs.506190
Alternative Splicing GalleryENSG00000183625
Gene ExpressionCCR3 [ NCBI-GEO ]   CCR3 [ EBI - ARRAY_EXPRESS ]   CCR3 [ SEEK ]   CCR3 [ MEM ]
Gene Expression Viewer (FireBrowse)CCR3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1232
GTEX Portal (Tissue expression)CCR3
Protein : pattern, domain, 3D structure
UniProt/SwissProtP51677   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP51677  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP51677
Splice isoforms : SwissVarP51677
PhosPhoSitePlusP51677
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)Chemokine_CCR3    Chemokine_rcpt    GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)CCR3
DMDM Disease mutations1232
Blocks (Seattle)CCR3
SuperfamilyP51677
Human Protein AtlasENSG00000183625
Peptide AtlasP51677
HPRD03167
IPIIPI00019957   IPI00791681   IPI00944675   IPI00927934   IPI00924670   
Protein Interaction databases
DIP (DOE-UCLA)P51677
IntAct (EBI)P51677
FunCoupENSG00000183625
BioGRIDCCR3
STRING (EMBL)CCR3
ZODIACCCR3
Ontologies - Pathways
QuickGOP51677
Ontology : AmiGOpositive regulation of endothelial cell proliferation  chemokine receptor activity  protein binding  plasma membrane  integral component of plasma membrane  chemotaxis  inflammatory response  cellular defense response  cell adhesion  adenylate cyclase-modulating G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  viral process  C-C chemokine receptor activity  C-C chemokine binding  positive regulation of angiogenesis  chemokine-mediated signaling pathway  
Ontology : EGO-EBIpositive regulation of endothelial cell proliferation  chemokine receptor activity  protein binding  plasma membrane  integral component of plasma membrane  chemotaxis  inflammatory response  cellular defense response  cell adhesion  adenylate cyclase-modulating G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  viral process  C-C chemokine receptor activity  C-C chemokine binding  positive regulation of angiogenesis  chemokine-mediated signaling pathway  
Pathways : BIOCARTASelective expression of chemokine receptors during T-cell polarization [Genes]    CCR3 signaling in Eosinophils [Genes]    The Role of Eosinophils in the Chemokine Network of Allergy [Genes]    IL 5 Signaling Pathway [Genes]   
Pathways : KEGGCytokine-cytokine receptor interaction    Chemokine signaling pathway    Viral carcinogenesis   
NDEx NetworkCCR3
Atlas of Cancer Signalling NetworkCCR3
Wikipedia pathwaysCCR3
Orthology - Evolution
OrthoDB1232
GeneTree (enSembl)ENSG00000183625
Phylogenetic Trees/Animal Genes : TreeFamCCR3
HOVERGENP51677
HOGENOMP51677
Homologs : HomoloGeneCCR3
Homology/Alignments : Family Browser (UCSC)CCR3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCCR3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CCR3
dbVarCCR3
ClinVarCCR3
1000_GenomesCCR3 
Exome Variant ServerCCR3
ExAC (Exome Aggregation Consortium)CCR3 (select the gene name)
Genetic variants : HAPMAP1232
Genomic Variants (DGV)CCR3 [DGVbeta]
DECIPHERCCR3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCCR3 
Mutations
ICGC Data PortalCCR3 
TCGA Data PortalCCR3 
Broad Tumor PortalCCR3
OASIS PortalCCR3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCCR3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCCR3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CCR3
DgiDB (Drug Gene Interaction Database)CCR3
DoCM (Curated mutations)CCR3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CCR3 (select a term)
intoGenCCR3
Cancer3DCCR3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601268   
Orphanet
MedgenCCR3
Genetic Testing Registry CCR3
NextProtP51677 [Medical]
TSGene1232
GENETestsCCR3
Target ValidationCCR3
Huge Navigator CCR3 [HugePedia]
snp3D : Map Gene to Disease1232
BioCentury BCIQCCR3
ClinGenCCR3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1232
Chemical/Pharm GKB GenePA26168
Clinical trialCCR3
Miscellaneous
canSAR (ICR)CCR3 (select the gene name)
Probes
Litterature
PubMed178 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCCR3
EVEXCCR3
GoPubMedCCR3
iHOPCCR3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:27:16 CEST 2017

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