Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CCR8 (C-C motif chemokine receptor 8)

Identity

Alias_namesCMKBRL2
CMKBR8
chemokine (C-C motif) receptor 8
Alias_symbol (synonym)CY6
TER1
CKR-L1
GPR-CY6
CDw198
Other aliasCC-CKR-8
CCR-8
CKRL1
GPRCY6
HGNC (Hugo) CCR8
LocusID (NCBI) 1237
Atlas_Id 53548
Location 3p22.1  [Link to chromosome band 3p22]
Location_base_pair Starts at 39329706 and ends at 39333680 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CCR8   1609
Cards
Entrez_Gene (NCBI)CCR8  1237  C-C motif chemokine receptor 8
AliasesCC-CKR-8; CCR-8; CDw198; CKRL1; 
CMKBR8; CMKBRL2; CY6; GPRCY6; TER1
GeneCards (Weizmann)CCR8
Ensembl hg19 (Hinxton)ENSG00000179934 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000179934 [Gene_View]  chr3:39329706-39333680 [Contig_View]  CCR8 [Vega]
ICGC DataPortalENSG00000179934
TCGA cBioPortalCCR8
AceView (NCBI)CCR8
Genatlas (Paris)CCR8
WikiGenes1237
SOURCE (Princeton)CCR8
Genetics Home Reference (NIH)CCR8
Genomic and cartography
GoldenPath hg38 (UCSC)CCR8  -     chr3:39329706-39333680 +  3p22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CCR8  -     3p22.1   [Description]    (hg19-Feb_2009)
EnsemblCCR8 - 3p22.1 [CytoView hg19]  CCR8 - 3p22.1 [CytoView hg38]
Mapping of homologs : NCBICCR8 [Mapview hg19]  CCR8 [Mapview hg38]
OMIM601834   
Gene and transcription
Genbank (Entrez)AF005210 AK314957 BC069067 BC074743 BC107152
RefSeq transcript (Entrez)NM_005201
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CCR8
Cluster EST : UnigeneHs.113222 [ NCBI ]
CGAP (NCI)Hs.113222
Alternative Splicing GalleryENSG00000179934
Gene ExpressionCCR8 [ NCBI-GEO ]   CCR8 [ EBI - ARRAY_EXPRESS ]   CCR8 [ SEEK ]   CCR8 [ MEM ]
Gene Expression Viewer (FireBrowse)CCR8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1237
GTEX Portal (Tissue expression)CCR8
Protein : pattern, domain, 3D structure
UniProt/SwissProtP51685   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP51685  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP51685
Splice isoforms : SwissVarP51685
PhosPhoSitePlusP51685
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)Chemokine_CCR8    Chemokine_rcpt    GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)CCR8
DMDM Disease mutations1237
Blocks (Seattle)CCR8
SuperfamilyP51685
Human Protein AtlasENSG00000179934
Peptide AtlasP51685
HPRD03497
IPIIPI00019985   IPI01013698   IPI00925421   
Protein Interaction databases
DIP (DOE-UCLA)P51685
IntAct (EBI)P51685
FunCoupENSG00000179934
BioGRIDCCR8
STRING (EMBL)CCR8
ZODIACCCR8
Ontologies - Pathways
QuickGOP51685
Ontology : AmiGOchemokine receptor activity  plasma membrane  integral component of plasma membrane  chemotaxis  immune response  cell adhesion  G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  coreceptor activity  C-C chemokine receptor activity  chemokine-mediated signaling pathway  
Ontology : EGO-EBIchemokine receptor activity  plasma membrane  integral component of plasma membrane  chemotaxis  immune response  cell adhesion  G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  coreceptor activity  C-C chemokine receptor activity  chemokine-mediated signaling pathway  
Pathways : KEGGCytokine-cytokine receptor interaction    Chemokine signaling pathway    Viral carcinogenesis   
NDEx NetworkCCR8
Atlas of Cancer Signalling NetworkCCR8
Wikipedia pathwaysCCR8
Orthology - Evolution
OrthoDB1237
GeneTree (enSembl)ENSG00000179934
Phylogenetic Trees/Animal Genes : TreeFamCCR8
HOVERGENP51685
HOGENOMP51685
Homologs : HomoloGeneCCR8
Homology/Alignments : Family Browser (UCSC)CCR8
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCCR8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CCR8
dbVarCCR8
ClinVarCCR8
1000_GenomesCCR8 
Exome Variant ServerCCR8
ExAC (Exome Aggregation Consortium)CCR8 (select the gene name)
Genetic variants : HAPMAP1237
Genomic Variants (DGV)CCR8 [DGVbeta]
DECIPHERCCR8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCCR8 
Mutations
ICGC Data PortalCCR8 
TCGA Data PortalCCR8 
Broad Tumor PortalCCR8
OASIS PortalCCR8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCCR8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCCR8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CCR8
DgiDB (Drug Gene Interaction Database)CCR8
DoCM (Curated mutations)CCR8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CCR8 (select a term)
intoGenCCR8
Cancer3DCCR8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601834   
Orphanet
MedgenCCR8
Genetic Testing Registry CCR8
NextProtP51685 [Medical]
TSGene1237
GENETestsCCR8
Target ValidationCCR8
Huge Navigator CCR8 [HugePedia]
snp3D : Map Gene to Disease1237
BioCentury BCIQCCR8
ClinGenCCR8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1237
Chemical/Pharm GKB GenePA26173
Clinical trialCCR8
Miscellaneous
canSAR (ICR)CCR8 (select the gene name)
Probes
Litterature
PubMed55 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCCR8
EVEXCCR8
GoPubMedCCR8
iHOPCCR8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:01:07 CEST 2017

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