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CCT3 (chaperonin containing TCP1 subunit 3)

Identity

Alias_namesTRIC5
chaperonin containing TCP1
Alias_symbol (synonym)Cctg
Other aliasCCT-gamma
CCTG
PIG48
TCP-1-gamma
HGNC (Hugo) CCT3
LocusID (NCBI) 7203
Atlas_Id 46436
Location 1q22  [Link to chromosome band 1q22]
Location_base_pair Starts at 156308961 and ends at 156338415 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AC011357.1 () / CCT3 (1q22)CCT3 (1q22) / C1orf61 (1q22)CCT3 (1q22) / CCT3 (1q22)
CCT3 (1q22) / HVCN1 (12q24.11)CCT3 (1q22) / RAC1 (7p22.1)CCT3 (1q22) / SYT2 (1q32.1)
CCT3 (1q22) / TRAF3IP1 (2q37.3)LOC100507412 (-) / CCT3 (1q22)MDM2 (12q15) / CCT3 (1q22)
POLR1A (2p11.2) / CCT3 (1q22)SMG5 (1q22) / CCT3 (1q22)AC011357.1 CCT3 1q22
CCT3 1q22 / SYT2 1q32.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CCT3   1616
Cards
Entrez_Gene (NCBI)CCT3  7203  chaperonin containing TCP1 subunit 3
AliasesCCT-gamma; CCTG; PIG48; TCP-1-gamma; 
TRIC5
GeneCards (Weizmann)CCT3
Ensembl hg19 (Hinxton)ENSG00000163468 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163468 [Gene_View]  chr1:156308961-156338415 [Contig_View]  CCT3 [Vega]
ICGC DataPortalENSG00000163468
TCGA cBioPortalCCT3
AceView (NCBI)CCT3
Genatlas (Paris)CCT3
WikiGenes7203
SOURCE (Princeton)CCT3
Genetics Home Reference (NIH)CCT3
Genomic and cartography
GoldenPath hg38 (UCSC)CCT3  -     chr1:156308961-156338415 -  1q22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CCT3  -     1q22   [Description]    (hg19-Feb_2009)
EnsemblCCT3 - 1q22 [CytoView hg19]  CCT3 - 1q22 [CytoView hg38]
Mapping of homologs : NCBICCT3 [Mapview hg19]  CCT3 [Mapview hg38]
OMIM600114   
Gene and transcription
Genbank (Entrez)AB208882 AK126400 AK293477 AK300765 AK308023
RefSeq transcript (Entrez)NM_001008800 NM_001008883 NM_005998
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CCT3
Cluster EST : UnigeneHs.491494 [ NCBI ]
CGAP (NCI)Hs.491494
Alternative Splicing GalleryENSG00000163468
Gene ExpressionCCT3 [ NCBI-GEO ]   CCT3 [ EBI - ARRAY_EXPRESS ]   CCT3 [ SEEK ]   CCT3 [ MEM ]
Gene Expression Viewer (FireBrowse)CCT3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7203
GTEX Portal (Tissue expression)CCT3
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49368   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP49368  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP49368
Splice isoforms : SwissVarP49368
PhosPhoSitePlusP49368
Domaine pattern : Prosite (Expaxy)TCP1_1 (PS00750)    TCP1_2 (PS00751)    TCP1_3 (PS00995)   
Domains : Interpro (EBI)Chap_CCT_gamma    Chaperone_TCP-1    Chaperonin_TCP-1_CS    Cpn60/TCP-1    GroEL-like_apical_dom    GROEL-like_equatorial    TCP-1-like_intermed   
Domain families : Pfam (Sanger)Cpn60_TCP1 (PF00118)   
Domain families : Pfam (NCBI)pfam00118   
Conserved Domain (NCBI)CCT3
DMDM Disease mutations7203
Blocks (Seattle)CCT3
SuperfamilyP49368
Human Protein AtlasENSG00000163468
Peptide AtlasP49368
HPRD08969
IPIIPI00553185   IPI00514218   IPI00513814   IPI00514032   IPI00513703   IPI00552715   IPI00974460   IPI00974552   IPI00977430   IPI00975528   IPI01010158   IPI00979444   
Protein Interaction databases
DIP (DOE-UCLA)P49368
IntAct (EBI)P49368
FunCoupENSG00000163468
BioGRIDCCT3
STRING (EMBL)CCT3
ZODIACCCT3
Ontologies - Pathways
QuickGOP49368
Ontology : AmiGOzona pellucida receptor complex  RNA binding  protein binding  ATP binding  cytosol  cytosol  chaperonin-containing T-complex  chaperonin-containing T-complex  cytoskeleton  microtubule  plasma membrane  protein folding  'de novo' protein folding  binding of sperm to zona pellucida  positive regulation of telomere maintenance via telomerase  myelin sheath  protein binding involved in protein folding  cell body  pore complex assembly  protein stabilization  unfolded protein binding  chaperone-mediated protein folding  extracellular exosome  toxin transport  positive regulation of protein localization to Cajal body  positive regulation of telomerase RNA localization to Cajal body  
Ontology : EGO-EBIzona pellucida receptor complex  RNA binding  protein binding  ATP binding  cytosol  cytosol  chaperonin-containing T-complex  chaperonin-containing T-complex  cytoskeleton  microtubule  plasma membrane  protein folding  'de novo' protein folding  binding of sperm to zona pellucida  positive regulation of telomere maintenance via telomerase  myelin sheath  protein binding involved in protein folding  cell body  pore complex assembly  protein stabilization  unfolded protein binding  chaperone-mediated protein folding  extracellular exosome  toxin transport  positive regulation of protein localization to Cajal body  positive regulation of telomerase RNA localization to Cajal body  
NDEx NetworkCCT3
Atlas of Cancer Signalling NetworkCCT3
Wikipedia pathwaysCCT3
Orthology - Evolution
OrthoDB7203
GeneTree (enSembl)ENSG00000163468
Phylogenetic Trees/Animal Genes : TreeFamCCT3
HOVERGENP49368
HOGENOMP49368
Homologs : HomoloGeneCCT3
Homology/Alignments : Family Browser (UCSC)CCT3
Gene fusions - Rearrangements
Fusion : MitelmanCCT3/SYT2 [1q22/1q32.1]  
Fusion: TCGAAC011357.1 CCT3 1q22 GBM
Fusion: TCGACCT3 1q22 SYT2 1q32.1 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCCT3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CCT3
dbVarCCT3
ClinVarCCT3
1000_GenomesCCT3 
Exome Variant ServerCCT3
ExAC (Exome Aggregation Consortium)CCT3 (select the gene name)
Genetic variants : HAPMAP7203
Genomic Variants (DGV)CCT3 [DGVbeta]
DECIPHERCCT3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCCT3 
Mutations
ICGC Data PortalCCT3 
TCGA Data PortalCCT3 
Broad Tumor PortalCCT3
OASIS PortalCCT3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCCT3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCCT3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CCT3
DgiDB (Drug Gene Interaction Database)CCT3
DoCM (Curated mutations)CCT3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CCT3 (select a term)
intoGenCCT3
Cancer3DCCT3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600114   
Orphanet
MedgenCCT3
Genetic Testing Registry CCT3
NextProtP49368 [Medical]
TSGene7203
GENETestsCCT3
Target ValidationCCT3
Huge Navigator CCT3 [HugePedia]
snp3D : Map Gene to Disease7203
BioCentury BCIQCCT3
ClinGenCCT3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7203
Chemical/Pharm GKB GenePA26180
Clinical trialCCT3
Miscellaneous
canSAR (ICR)CCT3 (select the gene name)
Probes
Litterature
PubMed113 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCCT3
EVEXCCT3
GoPubMedCCT3
iHOPCCT3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:27:18 CEST 2017

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