Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CCT8 (chaperonin containing TCP1 subunit 8)

Identity

Alias_namesC21orf112
chromosome 21 open reading frame 112
chaperonin containing TCP1, subunit 8 (theta)
Alias_symbol (synonym)Cctq
PRED71
Other aliasD21S246
HGNC (Hugo) CCT8
LocusID (NCBI) 10694
Atlas_Id 55943
Location 21q21.3  [Link to chromosome band 21q21]
Location_base_pair Starts at 29056322 and ends at 29073797 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CCT8 (21q21.3) / LHX4 (1q25.2)FBXO7 (22q12.3) / CCT8 (21q21.3)LOC100507412 (-) / CCT8 (21q21.3)
MTCL1 (18p11.22) / CCT8 (21q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CCT8   1623
Cards
Entrez_Gene (NCBI)CCT8  10694  chaperonin containing TCP1 subunit 8
AliasesC21orf112; Cctq; D21S246; PRED71
GeneCards (Weizmann)CCT8
Ensembl hg19 (Hinxton)ENSG00000156261 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000156261 [Gene_View]  chr21:29056322-29073797 [Contig_View]  CCT8 [Vega]
ICGC DataPortalENSG00000156261
TCGA cBioPortalCCT8
AceView (NCBI)CCT8
Genatlas (Paris)CCT8
WikiGenes10694
SOURCE (Princeton)CCT8
Genetics Home Reference (NIH)CCT8
Genomic and cartography
GoldenPath hg38 (UCSC)CCT8  -     chr21:29056322-29073797 -  21q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CCT8  -     21q21.3   [Description]    (hg19-Feb_2009)
EnsemblCCT8 - 21q21.3 [CytoView hg19]  CCT8 - 21q21.3 [CytoView hg38]
Mapping of homologs : NCBICCT8 [Mapview hg19]  CCT8 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK222490 AK293705 AK298801 AK308063 BC005220
RefSeq transcript (Entrez)NM_001282907 NM_001282908 NM_001282909 NM_006585
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CCT8
Cluster EST : UnigeneHs.125113 [ NCBI ]
CGAP (NCI)Hs.125113
Alternative Splicing GalleryENSG00000156261
Gene ExpressionCCT8 [ NCBI-GEO ]   CCT8 [ EBI - ARRAY_EXPRESS ]   CCT8 [ SEEK ]   CCT8 [ MEM ]
Gene Expression Viewer (FireBrowse)CCT8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10694
GTEX Portal (Tissue expression)CCT8
Protein : pattern, domain, 3D structure
UniProt/SwissProtP50990   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP50990  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP50990
Splice isoforms : SwissVarP50990
PhosPhoSitePlusP50990
Domaine pattern : Prosite (Expaxy)TCP1_1 (PS00750)    TCP1_2 (PS00751)    TCP1_3 (PS00995)   
Domains : Interpro (EBI)Chap_CCT_theta    Chaperone_TCP-1    Chaperonin_TCP-1_CS    Cpn60/TCP-1    GroEL-like_apical_dom    GROEL-like_equatorial    TCP-1-like_intermed   
Domain families : Pfam (Sanger)Cpn60_TCP1 (PF00118)   
Domain families : Pfam (NCBI)pfam00118   
Conserved Domain (NCBI)CCT8
DMDM Disease mutations10694
Blocks (Seattle)CCT8
SuperfamilyP50990
Human Protein AtlasENSG00000156261
Peptide AtlasP50990
HPRD10816
IPIIPI00784090   IPI01009326   IPI00794673   IPI00302925   IPI00797206   
Protein Interaction databases
DIP (DOE-UCLA)P50990
IntAct (EBI)P50990
FunCoupENSG00000156261
BioGRIDCCT8
STRING (EMBL)CCT8
ZODIACCCT8
Ontologies - Pathways
QuickGOP50990
Ontology : AmiGOzona pellucida receptor complex  protein binding  ATP binding  extracellular region  nucleoplasm  cytoplasm  centrosome  cytosol  cytosol  chaperonin-containing T-complex  chaperonin-containing T-complex  microtubule  cilium  protein folding  'de novo' protein folding  binding of sperm to zona pellucida  positive regulation of telomere maintenance via telomerase  secretory granule lumen  azurophil granule lumen  ATPase activity, coupled  neutrophil degranulation  protein binding involved in protein folding  cell body  intermediate filament cytoskeleton  cadherin binding  pore complex assembly  protein stabilization  unfolded protein binding  chaperone-mediated protein folding  extracellular exosome  toxin transport  ficolin-1-rich granule lumen  positive regulation of establishment of protein localization to telomere  positive regulation of protein localization to Cajal body  positive regulation of telomerase RNA localization to Cajal body  
Ontology : EGO-EBIzona pellucida receptor complex  protein binding  ATP binding  extracellular region  nucleoplasm  cytoplasm  centrosome  cytosol  cytosol  chaperonin-containing T-complex  chaperonin-containing T-complex  microtubule  cilium  protein folding  'de novo' protein folding  binding of sperm to zona pellucida  positive regulation of telomere maintenance via telomerase  secretory granule lumen  azurophil granule lumen  ATPase activity, coupled  neutrophil degranulation  protein binding involved in protein folding  cell body  intermediate filament cytoskeleton  cadherin binding  pore complex assembly  protein stabilization  unfolded protein binding  chaperone-mediated protein folding  extracellular exosome  toxin transport  ficolin-1-rich granule lumen  positive regulation of establishment of protein localization to telomere  positive regulation of protein localization to Cajal body  positive regulation of telomerase RNA localization to Cajal body  
NDEx NetworkCCT8
Atlas of Cancer Signalling NetworkCCT8
Wikipedia pathwaysCCT8
Orthology - Evolution
OrthoDB10694
GeneTree (enSembl)ENSG00000156261
Phylogenetic Trees/Animal Genes : TreeFamCCT8
HOVERGENP50990
HOGENOMP50990
Homologs : HomoloGeneCCT8
Homology/Alignments : Family Browser (UCSC)CCT8
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCCT8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CCT8
dbVarCCT8
ClinVarCCT8
1000_GenomesCCT8 
Exome Variant ServerCCT8
ExAC (Exome Aggregation Consortium)CCT8 (select the gene name)
Genetic variants : HAPMAP10694
Genomic Variants (DGV)CCT8 [DGVbeta]
DECIPHERCCT8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCCT8 
Mutations
ICGC Data PortalCCT8 
TCGA Data PortalCCT8 
Broad Tumor PortalCCT8
OASIS PortalCCT8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCCT8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCCT8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CCT8
DgiDB (Drug Gene Interaction Database)CCT8
DoCM (Curated mutations)CCT8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CCT8 (select a term)
intoGenCCT8
Cancer3DCCT8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenCCT8
Genetic Testing Registry CCT8
NextProtP50990 [Medical]
TSGene10694
GENETestsCCT8
Target ValidationCCT8
Huge Navigator CCT8 [HugePedia]
snp3D : Map Gene to Disease10694
BioCentury BCIQCCT8
ClinGenCCT8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10694
Chemical/Pharm GKB GenePA26186
Clinical trialCCT8
Miscellaneous
canSAR (ICR)CCT8 (select the gene name)
Probes
Litterature
PubMed102 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCCT8
EVEXCCT8
GoPubMedCCT8
iHOPCCT8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:01:10 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.