Atlas of Genetics and Cytogenetics in Oncology and Haematology

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CD14 (CD14 molecule)

Identity

Alias_namesCD14 antigen
Other alias-
HGNC (Hugo) CD14
LocusID (NCBI) 929
Atlas_Id 966
Location 5q31.3  [Link to chromosome band 5q31]
Location_base_pair Starts at 140631728 and ends at 140633701 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CD14 (5q31.3) / CD14 (5q31.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CD14   1628
Cards
Entrez_Gene (NCBI)CD14  929  CD14 molecule
Aliases
GeneCards (Weizmann)CD14
Ensembl hg19 (Hinxton)ENSG00000170458 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000170458 [Gene_View]  ENSG00000170458 [Sequence]  chr5:140631728-140633701 [Contig_View]  CD14 [Vega]
ICGC DataPortalENSG00000170458
TCGA cBioPortalCD14
AceView (NCBI)CD14
Genatlas (Paris)CD14
WikiGenes929
SOURCE (Princeton)CD14
Genetics Home Reference (NIH)CD14
Genomic and cartography
GoldenPath hg38 (UCSC)CD14  -     chr5:140631728-140633701 -  5q31.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CD14  -     5q31.3   [Description]    (hg19-Feb_2009)
GoldenPathCD14 - 5q31.3 [CytoView hg19]  CD14 - 5q31.3 [CytoView hg38]
ImmunoBaseENSG00000170458
Mapping of homologs : NCBICD14 [Mapview hg19]  CD14 [Mapview hg38]
OMIM158120   
Gene and transcription
Genbank (Entrez)AB446505 AF097942 AK313277 AY044269 BC010507
RefSeq transcript (Entrez)NM_000591 NM_001040021 NM_001174104 NM_001174105
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CD14
Alternative Splicing GalleryENSG00000170458
Gene ExpressionCD14 [ NCBI-GEO ]   CD14 [ EBI - ARRAY_EXPRESS ]   CD14 [ SEEK ]   CD14 [ MEM ]
Gene Expression Viewer (FireBrowse)CD14 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)929
GTEX Portal (Tissue expression)CD14
Human Protein AtlasENSG00000170458-CD14 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP08571   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP08571  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP08571
Splice isoforms : SwissVarP08571
PhosPhoSitePlusP08571
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)Leu-rich_rpt    LRR_dom_sf    Monocyte_diff_Ag_CD14   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)CD14
DMDM Disease mutations929
Blocks (Seattle)CD14
PDB (RSDB)4GLP   
PDB Europe4GLP   
PDB (PDBSum)4GLP   
PDB (IMB)4GLP   
Structural Biology KnowledgeBase4GLP   
SCOP (Structural Classification of Proteins)4GLP   
CATH (Classification of proteins structures)4GLP   
SuperfamilyP08571
Human Protein Atlas [tissue]ENSG00000170458-CD14 [tissue]
Peptide AtlasP08571
HPRD01151
IPIIPI00029260   IPI00967977   IPI00965602   IPI00983366   
Protein Interaction databases
DIP (DOE-UCLA)P08571
IntAct (EBI)P08571
FunCoupENSG00000170458
BioGRIDCD14
STRING (EMBL)CD14
ZODIACCD14
Ontologies - Pathways
QuickGOP08571
Ontology : AmiGOlipopolysaccharide binding  lipopolysaccharide binding  opsonin receptor activity  toll-like receptor signaling pathway  MyD88-dependent toll-like receptor signaling pathway  MyD88-independent toll-like receptor signaling pathway  protein binding  extracellular region  extracellular space  Golgi apparatus  plasma membrane  receptor-mediated endocytosis  phagocytosis  apoptotic process  inflammatory response  cell surface receptor signaling pathway  I-kappaB kinase/NF-kappaB signaling  response to heat  external side of plasma membrane  cell surface  endosome membrane  peptidoglycan receptor activity  secretory granule membrane  anchored component of external side of plasma membrane  lipopolysaccharide-mediated signaling pathway  response to magnesium ion  positive regulation of type I interferon production  positive regulation of interferon-gamma production  positive regulation of interferon-gamma production  positive regulation of tumor necrosis factor production  positive regulation of tumor necrosis factor production  negative regulation of MyD88-independent toll-like receptor signaling pathway  toll-like receptor 4 signaling pathway  toll-like receptor 4 signaling pathway  toll-like receptor 4 signaling pathway  response to tumor necrosis factor  TRIF-dependent toll-like receptor signaling pathway  toll-like receptor TLR1:TLR2 signaling pathway  toll-like receptor TLR6:TLR2 signaling pathway  neutrophil degranulation  innate immune response  membrane raft  membrane raft  response to ethanol  positive regulation of endocytosis  lipopolysaccharide receptor complex  lipopolysaccharide receptor complex  positive regulation of cytokine secretion  response to electrical stimulus  extracellular exosome  necroptotic process  lipoteichoic acid binding  cellular response to molecule of bacterial origin  cellular response to lipopolysaccharide  cellular response to lipopolysaccharide  cellular response to lipopolysaccharide  cellular response to lipoteichoic acid  lipopeptide binding  cellular response to diacyl bacterial lipopeptide  cellular response to triacyl bacterial lipopeptide  apoptotic signaling pathway  positive regulation of NIK/NF-kappaB signaling  positive regulation of NIK/NF-kappaB signaling  positive regulation of interleukin-8 secretion  positive regulation of interleukin-8 secretion  
Ontology : EGO-EBIlipopolysaccharide binding  lipopolysaccharide binding  opsonin receptor activity  toll-like receptor signaling pathway  MyD88-dependent toll-like receptor signaling pathway  MyD88-independent toll-like receptor signaling pathway  protein binding  extracellular region  extracellular space  Golgi apparatus  plasma membrane  receptor-mediated endocytosis  phagocytosis  apoptotic process  inflammatory response  cell surface receptor signaling pathway  I-kappaB kinase/NF-kappaB signaling  response to heat  external side of plasma membrane  cell surface  endosome membrane  peptidoglycan receptor activity  secretory granule membrane  anchored component of external side of plasma membrane  lipopolysaccharide-mediated signaling pathway  response to magnesium ion  positive regulation of type I interferon production  positive regulation of interferon-gamma production  positive regulation of interferon-gamma production  positive regulation of tumor necrosis factor production  positive regulation of tumor necrosis factor production  negative regulation of MyD88-independent toll-like receptor signaling pathway  toll-like receptor 4 signaling pathway  toll-like receptor 4 signaling pathway  toll-like receptor 4 signaling pathway  response to tumor necrosis factor  TRIF-dependent toll-like receptor signaling pathway  toll-like receptor TLR1:TLR2 signaling pathway  toll-like receptor TLR6:TLR2 signaling pathway  neutrophil degranulation  innate immune response  membrane raft  membrane raft  response to ethanol  positive regulation of endocytosis  lipopolysaccharide receptor complex  lipopolysaccharide receptor complex  positive regulation of cytokine secretion  response to electrical stimulus  extracellular exosome  necroptotic process  lipoteichoic acid binding  cellular response to molecule of bacterial origin  cellular response to lipopolysaccharide  cellular response to lipopolysaccharide  cellular response to lipopolysaccharide  cellular response to lipoteichoic acid  lipopeptide binding  cellular response to diacyl bacterial lipopeptide  cellular response to triacyl bacterial lipopeptide  apoptotic signaling pathway  positive regulation of NIK/NF-kappaB signaling  positive regulation of NIK/NF-kappaB signaling  positive regulation of interleukin-8 secretion  positive regulation of interleukin-8 secretion  
Pathways : KEGGMAPK signaling pathway    NF-kappa B signaling pathway    Phagosome    Toll-like receptor signaling pathway    Hematopoietic cell lineage    Regulation of actin cytoskeleton    Pathogenic Escherichia coli infection    Salmonella infection    Pertussis    Legionellosis    Amoebiasis    Tuberculosis    Transcriptional misregulation in cancer   
NDEx NetworkCD14
Atlas of Cancer Signalling NetworkCD14
Wikipedia pathwaysCD14
Orthology - Evolution
OrthoDB929
GeneTree (enSembl)ENSG00000170458
Phylogenetic Trees/Animal Genes : TreeFamCD14
HOGENOMP08571
Homologs : HomoloGeneCD14
Homology/Alignments : Family Browser (UCSC)CD14
Gene fusions - Rearrangements
Fusion : QuiverCD14
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCD14 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CD14
dbVarCD14
ClinVarCD14
1000_GenomesCD14 
Exome Variant ServerCD14
ExAC (Exome Aggregation Consortium)ENSG00000170458
GNOMAD BrowserENSG00000170458
Varsome BrowserCD14
Genetic variants : HAPMAP929
Genomic Variants (DGV)CD14 [DGVbeta]
DECIPHERCD14 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCD14 
Mutations
ICGC Data PortalCD14 
TCGA Data PortalCD14 
Broad Tumor PortalCD14
OASIS PortalCD14 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCD14  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCD14
Mutations and Diseases : HGMDCD14
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)TBsLVD Tuberculosis susceptibility Locus Variation Database
BioMutasearch CD14
DgiDB (Drug Gene Interaction Database)CD14
DoCM (Curated mutations)CD14 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CD14 (select a term)
intoGenCD14
Cancer3DCD14(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM158120   
Orphanet
DisGeNETCD14
MedgenCD14
Genetic Testing Registry CD14
NextProtP08571 [Medical]
TSGene929
GENETestsCD14
Target ValidationCD14
Huge Navigator CD14 [HugePedia]
snp3D : Map Gene to Disease929
BioCentury BCIQCD14
ClinGenCD14
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD929
Chemical/Pharm GKB GenePA26188
Clinical trialCD14
Miscellaneous
canSAR (ICR)CD14 (select the gene name)
DataMed IndexCD14
Probes
Litterature
PubMed499 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCD14
EVEXCD14
GoPubMedCD14
iHOPCD14
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Feb 19 16:36:44 CET 2020
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