CD164 (CD164 molecule)

2007-02-01  

Identity

HGNC
CD164
LOCATION
6q21
LOCUSID
8763
ALIAS
DFNA66,MGC-24,MGC-24v,MUC-24,endolyn
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 8763
MIM: 603356
HGNC: 1632
Ensembl: ENSG00000135535

Variants:

dbSNP: 8763
ClinVar: 8763
TCGA: ENSG00000135535
COSMIC: CD164

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000135535ENST00000275080Q04900
ENSG00000135535ENST00000310786Q04900
ENSG00000135535ENST00000324953Q04900
ENSG00000135535ENST00000413644Q04900
ENSG00000135535ENST00000504373D6R9B4
ENSG00000135535ENST00000512821Q04900

Expression (GTEx)

0
50
100
150
200
250
300
350
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
LysosomeKEGGko04142
LysosomeKEGGhsa04142

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
168595592006The role of sialomucin CD164 (MGC-24v or endolyn) in prostate cancer metastasis.34
159167202005Identification of CD13, CD107a, and CD164 as novel basophil-activation markers and dissection of two response patterns in time kinetics of IgE-dependent upregulation.29
170773242007Endolyn (CD164) modulates the CXCL12-mediated migration of umbilical cord blood CD133+ cells.27
224091832012Inhibiting CD164 expression in colon cancer cell line HCT116 leads to reduced cancer cell proliferation, mobility, and metastasis in vitro and in vivo.19
247568342014miR-219 inhibits the proliferation, migration and invasion of medulloblastoma cells by targeting CD164.16
240940052013CD164 regulates the tumorigenesis of ovarian surface epithelial cells through the SDF-1α/CXCR4 axis.11
311605682019A comprehensive single cell transcriptional landscape of human hematopoietic progenitors.11
169246782006The Drosophila ortholog of the endolysosomal membrane protein, endolyn, regulates cell proliferation.7
261974412015A Novel Locus Harbouring a Functional CD164 Nonsense Mutation Identified in a Large Danish Family with Nonsyndromic Hearing Impairment.7
265241862016Expression of CD164 on Malignant T cells in Sézary Syndrome.7

Citation

Dessen P

CD164 (CD164 molecule)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45919/cd164