CD24 (CD24 molecule)

2003-06-01  

Identity

HGNC
LOCATION
6q21
LOCUSID
ALIAS
CD24A
FUSION GENES

Other Information

Locus ID:

NCBI: 100133941
MIM: 600074
HGNC: 1645
Ensembl: ENSG00000272398

Variants:

dbSNP: 100133941
ClinVar: 100133941
TCGA: ENSG00000272398
COSMIC: CD24

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000272398ENST00000606017P25063
ENSG00000272398ENST00000610952P25063
ENSG00000272398ENST00000615659A0A087WW33
ENSG00000272398ENST00000619133P25063
ENSG00000272398ENST00000619869A0A087WU87
ENSG00000272398ENST00000620405A0A087WU21
ENSG00000272398ENST00000622315P25063

Expression (GTEx)

0
500
1000
1500

Pathways

PathwaySourceExternal ID
Hematopoietic cell lineageKEGGko04640
Hematopoietic cell lineageKEGGhsa04640
Developmental BiologyREACTOMER-HSA-1266738
Axon guidanceREACTOMER-HSA-422475
L1CAM interactionsREACTOMER-HSA-373760

References

Pubmed IDYearTitleCitations
216331652011The JAK2/STAT3 signaling pathway is required for growth of CD44⁺CD24⁻ stem cell-like breast cancer cells in human tumors.334
185590902008The CD44+/CD24- phenotype is enriched in basal-like breast tumors.223
156160152005Defective suppressor function in CD4(+)CD25(+) T-cells from patients with type 1 diabetes.215
217268332011CD24(+) liver tumor-initiating cells drive self-renewal and tumor initiation through STAT3-mediated NANOG regulation.205
218354332012CD44(+)/CD24(-/low) cancer stem/progenitor cells are more abundant in triple-negative invasive breast carcinoma phenotype and are associated with poor outcome.85
200198402009Twist modulates breast cancer stem cells by transcriptional regulation of CD24 expression.79
200198402009Twist modulates breast cancer stem cells by transcriptional regulation of CD24 expression.79
197251192009CD15, CD24, and CD29 define a surface biomarker code for neural lineage differentiation of stem cells.74
175400492007Human breast cancer stem cell markers CD44 and CD24: enriching for cells with functional properties in mice or in man?63
226107802012CD44+/CD24- ovarian cancer cells demonstrate cancer stem cell properties and correlate to survival.61

Citation

Dessen P

CD24 (CD24 molecule)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/973/cd24