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CD24 (CD24 molecule)

Identity

Alias_namesCD24 antigen (small cell lung carcinoma cluster 4 antigen)
Alias_symbol (synonym)CD24A
Other alias
HGNC (Hugo) CD24
LocusID (NCBI) 100133941
Atlas_Id 973
Location 6q21  [Link to chromosome band 6q21]
Location_base_pair Starts at 106969831 and ends at 106975627 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
GPAA1 (8q24.3) / CD24 (Yq11.222)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  Chronic Myelomonocytic Leukemia (CMML)


External links

Nomenclature
HGNC (Hugo)CD24   1645
Cards
Entrez_Gene (NCBI)CD24  100133941  CD24 molecule
AliasesCD24A
GeneCards (Weizmann)CD24
Ensembl hg19 (Hinxton)ENSG00000272398 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000272398 [Gene_View]  chr6:106969831-106975627 [Contig_View]  CD24 [Vega]
ICGC DataPortalENSG00000272398
TCGA cBioPortalCD24
AceView (NCBI)CD24
Genatlas (Paris)CD24
WikiGenes100133941
SOURCE (Princeton)CD24
Genetics Home Reference (NIH)CD24
Genomic and cartography
GoldenPath hg38 (UCSC)CD24  -     chr6:106969831-106975627 -  6q21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CD24  -     6q21   [Description]    (hg19-Feb_2009)
EnsemblCD24 - 6q21 [CytoView hg19]  CD24 - 6q21 [CytoView hg38]
Mapping of homologs : NCBICD24 [Mapview hg19]  CD24 [Mapview hg38]
OMIM600074   
Gene and transcription
Genbank (Entrez)AK026603 AK125531 AL535013 AU125939 BC064619
RefSeq transcript (Entrez)NM_001291737 NM_001291738 NM_001291739 NM_013230
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CD24
Cluster EST : UnigeneHs.712050 [ NCBI ]
CGAP (NCI)Hs.712050
Alternative Splicing GalleryENSG00000272398
Gene ExpressionCD24 [ NCBI-GEO ]   CD24 [ EBI - ARRAY_EXPRESS ]   CD24 [ SEEK ]   CD24 [ MEM ]
Gene Expression Viewer (FireBrowse)CD24 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)100133941
GTEX Portal (Tissue expression)CD24
Protein : pattern, domain, 3D structure
UniProt/SwissProtP25063   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP25063  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP25063
Splice isoforms : SwissVarP25063
PhosPhoSitePlusP25063
Domains : Interpro (EBI)CD24   
Domain families : Pfam (Sanger)CD24 (PF14984)   
Domain families : Pfam (NCBI)pfam14984   
Conserved Domain (NCBI)CD24
DMDM Disease mutations100133941
Blocks (Seattle)CD24
SuperfamilyP25063
Human Protein AtlasENSG00000272398
Peptide AtlasP25063
IPIIPI00012413   IPI00977388   
Protein Interaction databases
DIP (DOE-UCLA)P25063
IntAct (EBI)P25063
FunCoupENSG00000272398
BioGRIDCD24
STRING (EMBL)CD24
ZODIACCD24
Ontologies - Pathways
QuickGOP25063
Ontology : AmiGOresponse to hypoxia  cell activation  regulation of cytokine-mediated signaling pathway  response to molecule of bacterial origin  immune response-regulating cell surface receptor signaling pathway  signal transducer activity  protein binding  intracellular  positive regulation of cytosolic calcium ion concentration  cell surface  membrane  Wnt signaling pathway  single organismal cell-cell adhesion  cell migration  protein kinase binding  protein tyrosine kinase activator activity  regulation of epithelial cell differentiation  T cell costimulation  anchored component of external side of plasma membrane  B cell receptor transport into membrane raft  chemokine receptor transport out of membrane raft  negative regulation of transforming growth factor beta3 production  positive regulation of activated T cell proliferation  regulation of phosphorylation  cholesterol homeostasis  positive regulation of MAP kinase activity  regulation of MAPK cascade  response to estrogen  membrane raft  respiratory burst  positive regulation of protein tyrosine kinase activity  glomerular visceral epithelial cell differentiation  glomerular parietal epithelial cell differentiation  intrinsic apoptotic signaling pathway  positive regulation of nephron tubule epithelial cell differentiation  
Ontology : EGO-EBIresponse to hypoxia  cell activation  regulation of cytokine-mediated signaling pathway  response to molecule of bacterial origin  immune response-regulating cell surface receptor signaling pathway  signal transducer activity  protein binding  intracellular  positive regulation of cytosolic calcium ion concentration  cell surface  membrane  Wnt signaling pathway  single organismal cell-cell adhesion  cell migration  protein kinase binding  protein tyrosine kinase activator activity  regulation of epithelial cell differentiation  T cell costimulation  anchored component of external side of plasma membrane  B cell receptor transport into membrane raft  chemokine receptor transport out of membrane raft  negative regulation of transforming growth factor beta3 production  positive regulation of activated T cell proliferation  regulation of phosphorylation  cholesterol homeostasis  positive regulation of MAP kinase activity  regulation of MAPK cascade  response to estrogen  membrane raft  respiratory burst  positive regulation of protein tyrosine kinase activity  glomerular visceral epithelial cell differentiation  glomerular parietal epithelial cell differentiation  intrinsic apoptotic signaling pathway  positive regulation of nephron tubule epithelial cell differentiation  
Pathways : KEGGHematopoietic cell lineage   
NDEx NetworkCD24
Atlas of Cancer Signalling NetworkCD24
Wikipedia pathwaysCD24
Orthology - Evolution
OrthoDB100133941
GeneTree (enSembl)ENSG00000272398
Phylogenetic Trees/Animal Genes : TreeFamCD24
HOVERGENP25063
HOGENOMP25063
Homologs : HomoloGeneCD24
Homology/Alignments : Family Browser (UCSC)CD24
Gene fusions - Rearrangements
Fusion : MitelmanGPAA1/CD24 [8q24.3/Yq11.222]  [t(6;8)(p21;q24)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCD24 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CD24
dbVarCD24
ClinVarCD24
1000_GenomesCD24 
Exome Variant ServerCD24
ExAC (Exome Aggregation Consortium)CD24 (select the gene name)
Genetic variants : HAPMAP100133941
Genomic Variants (DGV)CD24 [DGVbeta]
DECIPHERCD24 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCD24 
Mutations
ICGC Data PortalCD24 
TCGA Data PortalCD24 
Broad Tumor PortalCD24
OASIS PortalCD24 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDCD24
BioMutasearch CD24
DgiDB (Drug Gene Interaction Database)CD24
DoCM (Curated mutations)CD24 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CD24 (select a term)
intoGenCD24
Cancer3DCD24(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600074   
Orphanet
MedgenCD24
Genetic Testing Registry CD24
NextProtP25063 [Medical]
TSGene100133941
GENETestsCD24
Target ValidationCD24
Huge Navigator CD24 [HugePedia]
snp3D : Map Gene to Disease100133941
BioCentury BCIQCD24
ClinGenCD24
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD100133941
Chemical/Pharm GKB GenePA26202
Clinical trialCD24
Miscellaneous
canSAR (ICR)CD24 (select the gene name)
Probes
Litterature
PubMed225 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCD24
EVEXCD24
GoPubMedCD24
iHOPCD24
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:27:23 CEST 2017

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