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CD24 (CD24 molecule)

Identity

Alias (NCBI)CD24A
HGNC (Hugo) CD24
HGNC Alias symbCD24A
HGNC Previous nameCD24 antigen (small cell lung carcinoma cluster 4 antigen)
LocusID (NCBI) 100133941
Atlas_Id 973
Location 6q21  [Link to chromosome band 6q21]
Location_base_pair Starts at 106969831 and ends at 106975465 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GPAA1 (8q24.3)::CD24 (Yq11.222)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 2 ]
  Chronic Myelomonocytic Leukemia (CMML)
t(X;6)(p11;q21) CD24::RBM3


External links

 

Nomenclature
HGNC (Hugo)CD24   1645
Cards
Entrez_Gene (NCBI)CD24    CD24 molecule
AliasesCD24A
GeneCards (Weizmann)CD24
Ensembl hg19 (Hinxton)ENSG00000272398 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000272398 [Gene_View]  ENSG00000272398 [Sequence]  chr6:106969831-106975465 [Contig_View]  CD24 [Vega]
ICGC DataPortalENSG00000272398
TCGA cBioPortalCD24
AceView (NCBI)CD24
Genatlas (Paris)CD24
SOURCE (Princeton)CD24
Genetics Home Reference (NIH)CD24
Genomic and cartography
GoldenPath hg38 (UCSC)CD24  -     chr6:106969831-106975465 -  6q21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CD24  -     6q21   [Description]    (hg19-Feb_2009)
GoldenPathCD24 - 6q21 [CytoView hg19]  CD24 - 6q21 [CytoView hg38]
ImmunoBaseENSG00000272398
Genome Data Viewer NCBICD24 [Mapview hg19]  
OMIM600074   
Gene and transcription
Genbank (Entrez)AK026603 AK125531 AL535013 AU125939 BC064619
RefSeq transcript (Entrez)NM_001291737 NM_001291738 NM_001291739 NM_001359084 NM_013230
Consensus coding sequences : CCDS (NCBI)CD24
Gene ExpressionCD24 [ NCBI-GEO ]   CD24 [ EBI - ARRAY_EXPRESS ]   CD24 [ SEEK ]   CD24 [ MEM ]
Gene Expression Viewer (FireBrowse)CD24 [ Firebrowse - Broad ]
GenevisibleExpression of CD24 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)100133941
GTEX Portal (Tissue expression)CD24
Human Protein AtlasENSG00000272398-CD24 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP25063   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP25063  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP25063
PhosPhoSitePlusP25063
Domains : Interpro (EBI)CD24   
Domain families : Pfam (Sanger)CD24 (PF14984)   
Domain families : Pfam (NCBI)pfam14984   
Conserved Domain (NCBI)CD24
SuperfamilyP25063
AlphaFold pdb e-kbP25063   
Human Protein Atlas [tissue]ENSG00000272398-CD24 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)P25063
IntAct (EBI)P25063
BioGRIDCD24
STRING (EMBL)CD24
ZODIACCD24
Ontologies - Pathways
QuickGOP25063
Ontology : AmiGOresponse to hypoxia  cell activation  regulation of cytokine-mediated signaling pathway  response to molecule of bacterial origin  immune response-regulating cell surface receptor signaling pathway  protein binding  positive regulation of cytosolic calcium ion concentration  cell surface  membrane  Wnt signaling pathway  cell migration  protein kinase binding  protein tyrosine kinase activator activity  regulation of epithelial cell differentiation  T cell costimulation  anchored component of external side of plasma membrane  B cell receptor transport into membrane raft  chemokine receptor transport out of membrane raft  negative regulation of transforming growth factor beta3 production  positive regulation of activated T cell proliferation  regulation of phosphorylation  cholesterol homeostasis  positive regulation of MAP kinase activity  regulation of MAPK cascade  response to estrogen  membrane raft  respiratory burst  positive regulation of protein tyrosine kinase activity  glomerular visceral epithelial cell differentiation  glomerular parietal epithelial cell differentiation  intrinsic apoptotic signaling pathway  cell-cell adhesion  positive regulation of nephron tubule epithelial cell differentiation  
Ontology : EGO-EBIresponse to hypoxia  cell activation  regulation of cytokine-mediated signaling pathway  response to molecule of bacterial origin  immune response-regulating cell surface receptor signaling pathway  protein binding  positive regulation of cytosolic calcium ion concentration  cell surface  membrane  Wnt signaling pathway  cell migration  protein kinase binding  protein tyrosine kinase activator activity  regulation of epithelial cell differentiation  T cell costimulation  anchored component of external side of plasma membrane  B cell receptor transport into membrane raft  chemokine receptor transport out of membrane raft  negative regulation of transforming growth factor beta3 production  positive regulation of activated T cell proliferation  regulation of phosphorylation  cholesterol homeostasis  positive regulation of MAP kinase activity  regulation of MAPK cascade  response to estrogen  membrane raft  respiratory burst  positive regulation of protein tyrosine kinase activity  glomerular visceral epithelial cell differentiation  glomerular parietal epithelial cell differentiation  intrinsic apoptotic signaling pathway  cell-cell adhesion  positive regulation of nephron tubule epithelial cell differentiation  
NDEx NetworkCD24
Atlas of Cancer Signalling NetworkCD24
Wikipedia pathwaysCD24
Orthology - Evolution
OrthoDB100133941
GeneTree (enSembl)ENSG00000272398
Phylogenetic Trees/Animal Genes : TreeFamCD24
Homologs : HomoloGeneCD24
Homology/Alignments : Family Browser (UCSC)CD24
Gene fusions - Rearrangements
Fusion : MitelmanGPAA1::CD24 [8q24.3/Yq11.222]  
Fusion : QuiverCD24
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCD24 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CD24
dbVarCD24
ClinVarCD24
MonarchCD24
1000_GenomesCD24 
Exome Variant ServerCD24
GNOMAD BrowserENSG00000272398
Varsome BrowserCD24
ACMGCD24 variants
VarityP25063
Genomic Variants (DGV)CD24 [DGVbeta]
DECIPHERCD24 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCD24 
Mutations
ICGC Data PortalCD24 
TCGA Data PortalCD24 
Broad Tumor PortalCD24
OASIS PortalCD24 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDCD24
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaCD24
DgiDB (Drug Gene Interaction Database)CD24
DoCM (Curated mutations)CD24
CIViC (Clinical Interpretations of Variants in Cancer)CD24
Cancer3DCD24
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600074   
Orphanet107   
DisGeNETCD24
MedgenCD24
Genetic Testing Registry CD24
NextProtP25063 [Medical]
GENETestsCD24
Target ValidationCD24
Huge Navigator CD24 [HugePedia]
ClinGenCD24
Clinical trials, drugs, therapy
MyCancerGenomeCD24
Protein Interactions : CTDCD24
Pharm GKB GenePA26202
PharosP25063
Clinical trialCD24
Miscellaneous
canSAR (ICR)CD24
HarmonizomeCD24
ARCHS4CD24
DataMed IndexCD24
Probes
Litterature
PubMed298 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCD24
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jan 20 12:26:25 CET 2022

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