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CD276 (CD276 molecule)

Identity

Alias (NCBI)4Ig-B7-H3
B7-H3
B7H3
B7RP-2
HGNC (Hugo) CD276
HGNC Alias symbB7-H3
B7H3
B7RP-2
HGNC Previous nameCD276 antigen
LocusID (NCBI) 80381
Atlas_Id 43652
Location 15q24.1  [Link to chromosome band 15q24]
Location_base_pair Starts at 73684281 and ends at 73714518 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CD276 (15q24.1) / INS-IGF2 (11p15.5)CD276 (15q24.1) / PARP16 (15q22.31)CD276 (15q24.1) / TSPAN15 (10q22.1)
CD276 15q24.1 / PARP16 15q22.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)CD276   19137
Cards
Entrez_Gene (NCBI)CD276    CD276 molecule
Aliases4Ig-B7-H3; B7-H3; B7H3; B7RP-2
GeneCards (Weizmann)CD276
Ensembl hg19 (Hinxton)ENSG00000103855 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000103855 [Gene_View]  ENSG00000103855 [Sequence]  chr15:73684281-73714518 [Contig_View]  CD276 [Vega]
ICGC DataPortalENSG00000103855
TCGA cBioPortalCD276
AceView (NCBI)CD276
Genatlas (Paris)CD276
SOURCE (Princeton)CD276
Genetics Home Reference (NIH)CD276
Genomic and cartography
GoldenPath hg38 (UCSC)CD276  -     chr15:73684281-73714518 +  15q24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CD276  -     15q24.1   [Description]    (hg19-Feb_2009)
GoldenPathCD276 - 15q24.1 [CytoView hg19]  CD276 - 15q24.1 [CytoView hg38]
ImmunoBaseENSG00000103855
Genome Data Viewer NCBICD276 [Mapview hg19]  
OMIM605715   
Gene and transcription
Genbank (Entrez)AF302102 AJ583695 AJ583696 AK074849 AK074997
RefSeq transcript (Entrez)NM_001024736 NM_001329628 NM_001329629 NM_025240
Consensus coding sequences : CCDS (NCBI)CD276
Gene ExpressionCD276 [ NCBI-GEO ]   CD276 [ EBI - ARRAY_EXPRESS ]   CD276 [ SEEK ]   CD276 [ MEM ]
Gene Expression Viewer (FireBrowse)CD276 [ Firebrowse - Broad ]
GenevisibleExpression of CD276 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80381
GTEX Portal (Tissue expression)CD276
Human Protein AtlasENSG00000103855-CD276 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5ZPR3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5ZPR3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5ZPR3
PhosPhoSitePlusQ5ZPR3
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_dom_sf    Ig-like_fold    Ig_C1-set    Ig_sub    Ig_sub2    Ig_V-set   
Domain families : Pfam (Sanger)V-set (PF07686)   
Domain families : Pfam (NCBI)pfam07686   
Domain families : Smart (EMBL)IG (SM00409)  IGc1 (SM00407)  IGc2 (SM00408)  IGv (SM00406)  
Conserved Domain (NCBI)CD276
SuperfamilyQ5ZPR3
AlphaFold pdb e-kbQ5ZPR3   
Human Protein Atlas [tissue]ENSG00000103855-CD276 [tissue]
HPRD05756
Protein Interaction databases
DIP (DOE-UCLA)Q5ZPR3
IntAct (EBI)Q5ZPR3
BioGRIDCD276
STRING (EMBL)CD276
ZODIACCD276
Ontologies - Pathways
QuickGOQ5ZPR3
Ontology : AmiGOregulation of cytokine production  signaling receptor binding  signaling receptor binding  protein binding  external side of plasma membrane  external side of plasma membrane  integral component of membrane  positive regulation of interferon-gamma production  positive regulation of T cell proliferation  T cell activation  regulation of immune response  T cell receptor signaling pathway  
Ontology : EGO-EBIregulation of cytokine production  signaling receptor binding  signaling receptor binding  protein binding  external side of plasma membrane  external side of plasma membrane  integral component of membrane  positive regulation of interferon-gamma production  positive regulation of T cell proliferation  T cell activation  regulation of immune response  T cell receptor signaling pathway  
Pathways : KEGGCell adhesion molecules (CAMs)   
NDEx NetworkCD276
Atlas of Cancer Signalling NetworkCD276
Wikipedia pathwaysCD276
Orthology - Evolution
OrthoDB80381
GeneTree (enSembl)ENSG00000103855
Phylogenetic Trees/Animal Genes : TreeFamCD276
Homologs : HomoloGeneCD276
Homology/Alignments : Family Browser (UCSC)CD276
Gene fusions - Rearrangements
Fusion : MitelmanCD276/PARP16 [15q24.1/15q22.31]  
Fusion : QuiverCD276
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCD276 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CD276
dbVarCD276
ClinVarCD276
MonarchCD276
1000_GenomesCD276 
Exome Variant ServerCD276
GNOMAD BrowserENSG00000103855
Varsome BrowserCD276
ACMGCD276 variants
VarityQ5ZPR3
Genomic Variants (DGV)CD276 [DGVbeta]
DECIPHERCD276 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCD276 
Mutations
ICGC Data PortalCD276 
TCGA Data PortalCD276 
Broad Tumor PortalCD276
OASIS PortalCD276 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCD276  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCD276
Mutations and Diseases : HGMDCD276
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaCD276
DgiDB (Drug Gene Interaction Database)CD276
DoCM (Curated mutations)CD276
CIViC (Clinical Interpretations of Variants in Cancer)CD276
Cancer3DCD276
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605715   
Orphanet
DisGeNETCD276
MedgenCD276
Genetic Testing Registry CD276
NextProtQ5ZPR3 [Medical]
GENETestsCD276
Target ValidationCD276
Huge Navigator CD276 [HugePedia]
ClinGenCD276
Clinical trials, drugs, therapy
MyCancerGenomeCD276
Protein Interactions : CTDCD276
Pharm GKB GenePA142672148
PharosQ5ZPR3
Clinical trialCD276
Miscellaneous
canSAR (ICR)CD276
HarmonizomeCD276
DataMed IndexCD276
Probes
Litterature
PubMed163 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCD276
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:02:57 CEST 2021

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