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CD276 (CD276 molecule)

Identity

Alias_namesCD276 antigen
Alias_symbol (synonym)B7-H3
B7H3
B7RP-2
Other alias4Ig-B7-H3
HGNC (Hugo) CD276
LocusID (NCBI) 80381
Atlas_Id 43652
Location 15q24.1  [Link to chromosome band 15q24]
Location_base_pair Starts at 73684281 and ends at 73714518 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CD276 (15q24.1) / INS-IGF2 (11p15.5)CD276 (15q24.1) / PARP16 (15q22.31)CD276 (15q24.1) / TSPAN15 (10q22.1)
CD276 15q24.1 / PARP16 15q22.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CD276   19137
Cards
Entrez_Gene (NCBI)CD276  80381  CD276 molecule
Aliases4Ig-B7-H3; B7-H3; B7H3; B7RP-2
GeneCards (Weizmann)CD276
Ensembl hg19 (Hinxton)ENSG00000103855 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000103855 [Gene_View]  chr15:73684281-73714518 [Contig_View]  CD276 [Vega]
ICGC DataPortalENSG00000103855
TCGA cBioPortalCD276
AceView (NCBI)CD276
Genatlas (Paris)CD276
WikiGenes80381
SOURCE (Princeton)CD276
Genetics Home Reference (NIH)CD276
Genomic and cartography
GoldenPath hg38 (UCSC)CD276  -     chr15:73684281-73714518 +  15q24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CD276  -     15q24.1   [Description]    (hg19-Feb_2009)
EnsemblCD276 - 15q24.1 [CytoView hg19]  CD276 - 15q24.1 [CytoView hg38]
Mapping of homologs : NCBICD276 [Mapview hg19]  CD276 [Mapview hg38]
OMIM605715   
Gene and transcription
Genbank (Entrez)AF302102 AJ583695 AJ583696 AK074849 AK074997
RefSeq transcript (Entrez)NM_001024736 NM_001329628 NM_001329629 NM_025240
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CD276
Cluster EST : UnigeneHs.744915 [ NCBI ]
CGAP (NCI)Hs.744915
Alternative Splicing GalleryENSG00000103855
Gene ExpressionCD276 [ NCBI-GEO ]   CD276 [ EBI - ARRAY_EXPRESS ]   CD276 [ SEEK ]   CD276 [ MEM ]
Gene Expression Viewer (FireBrowse)CD276 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80381
GTEX Portal (Tissue expression)CD276
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5ZPR3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5ZPR3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5ZPR3
Splice isoforms : SwissVarQ5ZPR3
PhosPhoSitePlusQ5ZPR3
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_C1-set    Ig_sub    Ig_sub2    Ig_V-set   
Domain families : Pfam (Sanger)V-set (PF07686)   
Domain families : Pfam (NCBI)pfam07686   
Domain families : Smart (EMBL)IG (SM00409)  IGc1 (SM00407)  IGc2 (SM00408)  IGv (SM00406)  
Conserved Domain (NCBI)CD276
DMDM Disease mutations80381
Blocks (Seattle)CD276
SuperfamilyQ5ZPR3
Human Protein AtlasENSG00000103855
Peptide AtlasQ5ZPR3
HPRD05756
IPIIPI00410488   IPI00019275   IPI00441094   IPI00719044   IPI00909601   IPI01011941   
Protein Interaction databases
DIP (DOE-UCLA)Q5ZPR3
IntAct (EBI)Q5ZPR3
FunCoupENSG00000103855
BioGRIDCD276
STRING (EMBL)CD276
ZODIACCD276
Ontologies - Pathways
QuickGOQ5ZPR3
Ontology : AmiGOreceptor binding  protein binding  immune response  cell proliferation  external side of plasma membrane  integral component of membrane  positive regulation of T cell proliferation  T cell activation  positive regulation of interferon-gamma biosynthetic process  regulation of immune response  extracellular exosome  
Ontology : EGO-EBIreceptor binding  protein binding  immune response  cell proliferation  external side of plasma membrane  integral component of membrane  positive regulation of T cell proliferation  T cell activation  positive regulation of interferon-gamma biosynthetic process  regulation of immune response  extracellular exosome  
Pathways : KEGGCell adhesion molecules (CAMs)   
NDEx NetworkCD276
Atlas of Cancer Signalling NetworkCD276
Wikipedia pathwaysCD276
Orthology - Evolution
OrthoDB80381
GeneTree (enSembl)ENSG00000103855
Phylogenetic Trees/Animal Genes : TreeFamCD276
HOVERGENQ5ZPR3
HOGENOMQ5ZPR3
Homologs : HomoloGeneCD276
Homology/Alignments : Family Browser (UCSC)CD276
Gene fusions - Rearrangements
Fusion : MitelmanCD276/PARP16 [15q24.1/15q22.31]  
Fusion: TCGACD276 15q24.1 PARP16 15q22.31 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCD276 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CD276
dbVarCD276
ClinVarCD276
1000_GenomesCD276 
Exome Variant ServerCD276
ExAC (Exome Aggregation Consortium)CD276 (select the gene name)
Genetic variants : HAPMAP80381
Genomic Variants (DGV)CD276 [DGVbeta]
DECIPHERCD276 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCD276 
Mutations
ICGC Data PortalCD276 
TCGA Data PortalCD276 
Broad Tumor PortalCD276
OASIS PortalCD276 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCD276  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCD276
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CD276
DgiDB (Drug Gene Interaction Database)CD276
DoCM (Curated mutations)CD276 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CD276 (select a term)
intoGenCD276
Cancer3DCD276(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605715   
Orphanet
MedgenCD276
Genetic Testing Registry CD276
NextProtQ5ZPR3 [Medical]
TSGene80381
GENETestsCD276
Target ValidationCD276
Huge Navigator CD276 [HugePedia]
snp3D : Map Gene to Disease80381
BioCentury BCIQCD276
ClinGenCD276
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD80381
Chemical/Pharm GKB GenePA142672148
Clinical trialCD276
Miscellaneous
canSAR (ICR)CD276 (select the gene name)
Probes
Litterature
PubMed94 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCD276
EVEXCD276
GoPubMedCD276
iHOPCD276
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:01:16 CEST 2017

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