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CD33 (CD33 molecule)

Identity

Alias_namesCD33 antigen (gp67)
Alias_symbol (synonym)SIGLEC3
SIGLEC-3
p67
FLJ00391
Other alias
HGNC (Hugo) CD33
LocusID (NCBI) 945
Atlas_Id 974
Location 19q13.41  [Link to chromosome band 19q13]
Location_base_pair Starts at 51728335 and ends at 51743274 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CD33 (19q13.41) / LOC100507412 (-)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CD33   1659
Cards
Entrez_Gene (NCBI)CD33  945  CD33 molecule
AliasesSIGLEC-3; SIGLEC3; p67
GeneCards (Weizmann)CD33
Ensembl hg19 (Hinxton)ENSG00000105383 [Gene_View]  chr19:51728335-51743274 [Contig_View]  CD33 [Vega]
Ensembl hg38 (Hinxton)ENSG00000105383 [Gene_View]  chr19:51728335-51743274 [Contig_View]  CD33 [Vega]
ICGC DataPortalENSG00000105383
TCGA cBioPortalCD33
AceView (NCBI)CD33
Genatlas (Paris)CD33
WikiGenes945
SOURCE (Princeton)CD33
Genetics Home Reference (NIH)CD33
Genomic and cartography
GoldenPath hg19 (UCSC)CD33  -     chr19:51728335-51743274 +  19q13.41   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CD33  -     19q13.41   [Description]    (hg38-Dec_2013)
EnsemblCD33 - 19q13.41 [CytoView hg19]  CD33 - 19q13.41 [CytoView hg38]
Mapping of homologs : NCBICD33 [Mapview hg19]  CD33 [Mapview hg38]
OMIM159590   
Gene and transcription
Genbank (Entrez)AK090470 AK293934 AK304810 AK309558 AW007749
RefSeq transcript (Entrez)NM_001082618 NM_001177608 NM_001772
RefSeq genomic (Entrez)NC_000019 NC_018930 NT_011109 NW_004929415
Consensus coding sequences : CCDS (NCBI)CD33
Cluster EST : UnigeneHs.83731 [ NCBI ]
CGAP (NCI)Hs.83731
Alternative Splicing GalleryENSG00000105383
Gene ExpressionCD33 [ NCBI-GEO ]   CD33 [ EBI - ARRAY_EXPRESS ]   CD33 [ SEEK ]   CD33 [ MEM ]
Gene Expression Viewer (FireBrowse)CD33 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)945
GTEX Portal (Tissue expression)CD33
Protein : pattern, domain, 3D structure
UniProt/SwissProtP20138   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP20138  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP20138
Splice isoforms : SwissVarP20138
PhosPhoSitePlusP20138
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_sub    Ig_V-set    Immunoglobulin   
Domain families : Pfam (Sanger)ig (PF00047)    V-set (PF07686)   
Domain families : Pfam (NCBI)pfam00047    pfam07686   
Domain families : Smart (EMBL)IG (SM00409)  
Conserved Domain (NCBI)CD33
DMDM Disease mutations945
Blocks (Seattle)CD33
SuperfamilyP20138
Human Protein AtlasENSG00000105383
Peptide AtlasP20138
HPRD01165
IPIIPI00022203   IPI00910723   IPI00168720   IPI00844575   IPI00964702   
Protein Interaction databases
DIP (DOE-UCLA)P20138
IntAct (EBI)P20138
FunCoupENSG00000105383
BioGRIDCD33
STRING (EMBL)CD33
ZODIACCD33
Ontologies - Pathways
QuickGOP20138
Ontology : AmiGOreceptor activity  protein binding  plasma membrane  integral component of plasma membrane  cell adhesion  signal transduction  cell-cell signaling  negative regulation of cell proliferation  external side of plasma membrane  carbohydrate binding  regulation of immune response  extracellular exosome  
Ontology : EGO-EBIreceptor activity  protein binding  plasma membrane  integral component of plasma membrane  cell adhesion  signal transduction  cell-cell signaling  negative regulation of cell proliferation  external side of plasma membrane  carbohydrate binding  regulation of immune response  extracellular exosome  
Pathways : BIOCARTADendritic cells in regulating TH1 and TH2 Development [Genes]   
Pathways : KEGGHematopoietic cell lineage   
NDEx NetworkCD33
Atlas of Cancer Signalling NetworkCD33
Wikipedia pathwaysCD33
Orthology - Evolution
OrthoDB945
GeneTree (enSembl)ENSG00000105383
Phylogenetic Trees/Animal Genes : TreeFamCD33
HOVERGENP20138
HOGENOMP20138
Homologs : HomoloGeneCD33
Homology/Alignments : Family Browser (UCSC)CD33
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCD33 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CD33
dbVarCD33
ClinVarCD33
1000_GenomesCD33 
Exome Variant ServerCD33
ExAC (Exome Aggregation Consortium)CD33 (select the gene name)
Genetic variants : HAPMAP945
Genomic Variants (DGV)CD33 [DGVbeta]
DECIPHER (Syndromes)19:51728335-51743274  ENSG00000105383
CONAN: Copy Number AnalysisCD33 
Mutations
ICGC Data PortalCD33 
TCGA Data PortalCD33 
Broad Tumor PortalCD33
OASIS PortalCD33 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCD33  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCD33
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CD33
DgiDB (Drug Gene Interaction Database)CD33
DoCM (Curated mutations)CD33 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CD33 (select a term)
intoGenCD33
Cancer3DCD33(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM159590   
Orphanet
MedgenCD33
Genetic Testing Registry CD33
NextProtP20138 [Medical]
TSGene945
GENETestsCD33
Huge Navigator CD33 [HugePedia]
snp3D : Map Gene to Disease945
BioCentury BCIQCD33
ClinGenCD33
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD945
Chemical/Pharm GKB GenePA26210
Clinical trialCD33
Miscellaneous
canSAR (ICR)CD33 (select the gene name)
Probes
Litterature
PubMed75 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCD33
EVEXCD33
GoPubMedCD33
iHOPCD33
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 14:55:39 CEST 2017

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