Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CD36 (CD36 molecule)

Identity

Alias_namesCD36 antigen (collagen type I receptor, thrombospondin receptor)
CD36 molecule (thrombospondin receptor)
Alias_symbol (synonym)SCARB3
GPIV
FAT
GP4
GP3B
Other aliasBDPLT10
CHDS7
PASIV
HGNC (Hugo) CD36
LocusID (NCBI) 948
Atlas_Id 976
Location 7q21.11  [Link to chromosome band 7q21]
Location_base_pair Starts at 80602207 and ends at 80674418 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CD36 (7q21.11) / DCN (12q21.33)CD36 (7q21.11) / TRANK1 (3p22.2)NCOA3 (20q13.12) / CD36 (7q21.11)
SEMA3C (7q21.11) / CD36 (7q21.11)SEMA3C 7q21.11 / CD36 7q21.11

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  SEMA3C/CD36 (7q21)


External links

Nomenclature
HGNC (Hugo)CD36   1663
Cards
Entrez_Gene (NCBI)CD36  948  CD36 molecule
AliasesBDPLT10; CHDS7; FAT; GP3B; 
GP4; GPIV; PASIV; SCARB3
GeneCards (Weizmann)CD36
Ensembl hg19 (Hinxton)ENSG00000135218 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000135218 [Gene_View]  ENSG00000135218 [Sequence]  chr7:80602207-80674418 [Contig_View]  CD36 [Vega]
ICGC DataPortalENSG00000135218
TCGA cBioPortalCD36
AceView (NCBI)CD36
Genatlas (Paris)CD36
WikiGenes948
SOURCE (Princeton)CD36
Genetics Home Reference (NIH)CD36
Genomic and cartography
GoldenPath hg38 (UCSC)CD36  -     chr7:80602207-80674418 +  7q21.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CD36  -     7q21.11   [Description]    (hg19-Feb_2009)
EnsemblCD36 - 7q21.11 [CytoView hg19]  CD36 - 7q21.11 [CytoView hg38]
Mapping of homologs : NCBICD36 [Mapview hg19]  CD36 [Mapview hg38]
OMIM173510   608404   610938   611162   
Gene and transcription
Genbank (Entrez)AA846141 AK057690 AK096858 AK129899 AK300101
RefSeq transcript (Entrez)NM_000072 NM_001001547 NM_001001548 NM_001127443 NM_001127444 NM_001289908 NM_001289909 NM_001289911
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CD36
Cluster EST : UnigeneHs.120949 [ NCBI ]
CGAP (NCI)Hs.120949
Alternative Splicing GalleryENSG00000135218
Gene ExpressionCD36 [ NCBI-GEO ]   CD36 [ EBI - ARRAY_EXPRESS ]   CD36 [ SEEK ]   CD36 [ MEM ]
Gene Expression Viewer (FireBrowse)CD36 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)948
GTEX Portal (Tissue expression)CD36
Human Protein AtlasENSG00000135218-CD36 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP16671   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP16671  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP16671
Splice isoforms : SwissVarP16671
PhosPhoSitePlusP16671
Domains : Interpro (EBI)CD36/SCARB1/SNMP1    CD36_chordates    CD36_fam   
Domain families : Pfam (Sanger)CD36 (PF01130)   
Domain families : Pfam (NCBI)pfam01130   
Conserved Domain (NCBI)CD36
DMDM Disease mutations948
Blocks (Seattle)CD36
PDB (SRS)5LGD   
PDB (PDBSum)5LGD   
PDB (IMB)5LGD   
PDB (RSDB)5LGD   
Structural Biology KnowledgeBase5LGD   
SCOP (Structural Classification of Proteins)5LGD   
CATH (Classification of proteins structures)5LGD   
SuperfamilyP16671
Human Protein Atlas [tissue]ENSG00000135218-CD36 [tissue]
Peptide AtlasP16671
HPRD01430
IPIIPI00418495   IPI00927433   IPI01015458   IPI00927926   IPI00745287   IPI00977670   IPI00926723   IPI01008866   IPI01012524   IPI00924451   IPI00924653   IPI00982787   IPI01008888   IPI01010516   
Protein Interaction databases
DIP (DOE-UCLA)P16671
IntAct (EBI)P16671
FunCoupENSG00000135218
BioGRIDCD36
STRING (EMBL)CD36
ZODIACCD36
Ontologies - Pathways
QuickGOP16671
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  amyloid-beta binding  positive regulation of cell-matrix adhesion  toll-like receptor signaling pathway  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  platelet degranulation  MyD88-dependent toll-like receptor signaling pathway  low-density lipoprotein particle receptor activity  low-density lipoprotein particle receptor activity  scavenger receptor activity  protein binding  extracellular space  intracellular  Golgi apparatus  plasma membrane  plasma membrane  integral component of plasma membrane  lipid metabolic process  receptor-mediated endocytosis  phagocytosis, recognition  cell adhesion  positive regulation of cytosolic calcium ion concentration  nitric oxide mediated signal transduction  blood coagulation  high-density lipoprotein particle binding  lipid binding  external side of plasma membrane  cell surface  cell surface  positive regulation of gene expression  positive regulation of macrophage derived foam cell differentiation  positive regulation of cholesterol storage  positive regulation of cell death  membrane  apical plasma membrane  regulation of lipid metabolic process  cytokine-mediated signaling pathway  lipid storage  cGMP-mediated signaling  low-density lipoprotein particle binding  positive regulation of blood coagulation  intestinal cholesterol absorption  cholesterol transport  endocytic vesicle membrane  platelet alpha granule membrane  brush border membrane  receptor internalization  positive regulation of interleukin-12 production  positive regulation of interleukin-6 production  positive regulation of tumor necrosis factor production  response to lipid  regulation of toll-like receptor signaling pathway  triglyceride transport  plasma lipoprotein particle clearance  low-density lipoprotein particle clearance  Toll-like receptor binding  specific granule membrane  response to stilbenoid  toll-like receptor TLR6:TLR2 signaling pathway  negative regulation of protein import into nucleus  lipoprotein transport  lipoprotein transport  positive regulation of I-kappaB kinase/NF-kappaB signaling  receptor complex  apoptotic cell clearance  neutrophil degranulation  regulation of protein heterodimerization activity  negative regulation of growth of symbiont in host  long-chain fatty acid import  membrane raft  phagocytic vesicle  positive regulation of nitric oxide biosynthetic process  transforming growth factor beta binding  interleukin-1 beta secretion  positive regulation of peptidyl-tyrosine phosphorylation  defense response to Gram-positive bacterium  intestinal absorption  sensory perception of taste  positive regulation of NF-kappaB transcription factor activity  low-density lipoprotein particle mediated signaling  positive regulation of phagocytosis, engulfment  positive regulation of macrophage cytokine production  thrombospondin receptor activity  positive regulation of ERK1 and ERK2 cascade  cholesterol import  response to fatty acid  response to linoleic acid  lipoteichoic acid receptor activity  cellular response to lipopolysaccharide  cellular response to lipoteichoic acid  cellular response to low-density lipoprotein particle stimulus  cellular response to hydroperoxide  cellular response to diacyl bacterial lipopeptide  lipoprotein particle binding  energy homeostasis  cellular response to oxidised low-density lipoprotein particle stimulus  oxidised low-density lipoprotein particle clearance  oxidised low-density lipoprotein particle receptor activity  positive regulation of NLRP3 inflammasome complex assembly  positive regulation of reactive oxygen species biosynthetic process  cellular response to amyloid-beta  amyloid fibril formation  regulation of removal of superoxide radicals  positive regulation of blood microparticle formation  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  amyloid-beta binding  positive regulation of cell-matrix adhesion  toll-like receptor signaling pathway  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  platelet degranulation  MyD88-dependent toll-like receptor signaling pathway  low-density lipoprotein particle receptor activity  low-density lipoprotein particle receptor activity  scavenger receptor activity  protein binding  extracellular space  intracellular  Golgi apparatus  plasma membrane  plasma membrane  integral component of plasma membrane  lipid metabolic process  receptor-mediated endocytosis  phagocytosis, recognition  cell adhesion  positive regulation of cytosolic calcium ion concentration  nitric oxide mediated signal transduction  blood coagulation  high-density lipoprotein particle binding  lipid binding  external side of plasma membrane  cell surface  cell surface  positive regulation of gene expression  positive regulation of macrophage derived foam cell differentiation  positive regulation of cholesterol storage  positive regulation of cell death  membrane  apical plasma membrane  regulation of lipid metabolic process  cytokine-mediated signaling pathway  lipid storage  cGMP-mediated signaling  low-density lipoprotein particle binding  positive regulation of blood coagulation  intestinal cholesterol absorption  cholesterol transport  endocytic vesicle membrane  platelet alpha granule membrane  brush border membrane  receptor internalization  positive regulation of interleukin-12 production  positive regulation of interleukin-6 production  positive regulation of tumor necrosis factor production  response to lipid  regulation of toll-like receptor signaling pathway  triglyceride transport  plasma lipoprotein particle clearance  low-density lipoprotein particle clearance  Toll-like receptor binding  specific granule membrane  response to stilbenoid  toll-like receptor TLR6:TLR2 signaling pathway  negative regulation of protein import into nucleus  lipoprotein transport  lipoprotein transport  positive regulation of I-kappaB kinase/NF-kappaB signaling  receptor complex  apoptotic cell clearance  neutrophil degranulation  regulation of protein heterodimerization activity  negative regulation of growth of symbiont in host  long-chain fatty acid import  membrane raft  phagocytic vesicle  positive regulation of nitric oxide biosynthetic process  transforming growth factor beta binding  interleukin-1 beta secretion  positive regulation of peptidyl-tyrosine phosphorylation  defense response to Gram-positive bacterium  intestinal absorption  sensory perception of taste  positive regulation of NF-kappaB transcription factor activity  low-density lipoprotein particle mediated signaling  positive regulation of phagocytosis, engulfment  positive regulation of macrophage cytokine production  thrombospondin receptor activity  positive regulation of ERK1 and ERK2 cascade  cholesterol import  response to fatty acid  response to linoleic acid  lipoteichoic acid receptor activity  cellular response to lipopolysaccharide  cellular response to lipoteichoic acid  cellular response to low-density lipoprotein particle stimulus  cellular response to hydroperoxide  cellular response to diacyl bacterial lipopeptide  lipoprotein particle binding  energy homeostasis  cellular response to oxidised low-density lipoprotein particle stimulus  oxidised low-density lipoprotein particle clearance  oxidised low-density lipoprotein particle receptor activity  positive regulation of NLRP3 inflammasome complex assembly  positive regulation of reactive oxygen species biosynthetic process  cellular response to amyloid-beta  amyloid fibril formation  regulation of removal of superoxide radicals  positive regulation of blood microparticle formation  
Pathways : KEGGPPAR signaling pathway    Phagosome    ECM-receptor interaction    Hematopoietic cell lineage    Adipocytokine signaling pathway    Fat digestion and absorption    Malaria   
NDEx NetworkCD36
Atlas of Cancer Signalling NetworkCD36
Wikipedia pathwaysCD36
Orthology - Evolution
OrthoDB948
GeneTree (enSembl)ENSG00000135218
Phylogenetic Trees/Animal Genes : TreeFamCD36
HOVERGENP16671
HOGENOMP16671
Homologs : HomoloGeneCD36
Homology/Alignments : Family Browser (UCSC)CD36
Gene fusions - Rearrangements
Fusion : MitelmanSEMA3C/CD36 [7q21.11/7q21.11]  [t(7;7)(q21;q21)]  
Fusion PortalSEMA3C 7q21.11 CD36 7q21.11 LUSC
Fusion : QuiverCD36
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCD36 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CD36
dbVarCD36
ClinVarCD36
1000_GenomesCD36 
Exome Variant ServerCD36
ExAC (Exome Aggregation Consortium)ENSG00000135218
GNOMAD BrowserENSG00000135218
Varsome BrowserCD36
Genetic variants : HAPMAP948
Genomic Variants (DGV)CD36 [DGVbeta]
DECIPHERCD36 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCD36 
Mutations
ICGC Data PortalCD36 
TCGA Data PortalCD36 
Broad Tumor PortalCD36
OASIS PortalCD36 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCD36  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCD36
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CD36
DgiDB (Drug Gene Interaction Database)CD36
DoCM (Curated mutations)CD36 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CD36 (select a term)
intoGenCD36
Cancer3DCD36(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM173510    608404    610938    611162   
Orphanet
DisGeNETCD36
MedgenCD36
Genetic Testing Registry CD36
NextProtP16671 [Medical]
TSGene948
GENETestsCD36
Target ValidationCD36
Huge Navigator CD36 [HugePedia]
snp3D : Map Gene to Disease948
BioCentury BCIQCD36
ClinGenCD36
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD948
Chemical/Pharm GKB GenePA26212
Clinical trialCD36
Miscellaneous
canSAR (ICR)CD36 (select the gene name)
Probes
Litterature
PubMed399 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCD36
EVEXCD36
GoPubMedCD36
iHOPCD36
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Aug 27 11:14:04 CEST 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.