Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CD3G (CD3g molecule)

Identity

Alias_namesCD3g antigen, gamma polypeptide (TiT3 complex)
CD3g molecule, gamma (CD3-TCR complex)
Other aliasCD3-GAMMA
IMD17
T3G
HGNC (Hugo) CD3G
LocusID (NCBI) 917
Atlas_Id 52425
Location 11q23.3  [Link to chromosome band 11q23]
Location_base_pair Starts at 118344344 and ends at 118353782 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CD3G (11q23.3) / TRIM10 (6p22.1)FXYD6 (11q23.3) / CD3G (11q23.3)FXYD6 11q23.3 / CD3G 11q23.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CD3G   1675
LRG (Locus Reference Genomic)LRG_39
Cards
Entrez_Gene (NCBI)CD3G  917  CD3g molecule
AliasesCD3-GAMMA; IMD17; T3G
GeneCards (Weizmann)CD3G
Ensembl hg19 (Hinxton)ENSG00000160654 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000160654 [Gene_View]  chr11:118344344-118353782 [Contig_View]  CD3G [Vega]
ICGC DataPortalENSG00000160654
TCGA cBioPortalCD3G
AceView (NCBI)CD3G
Genatlas (Paris)CD3G
WikiGenes917
SOURCE (Princeton)CD3G
Genetics Home Reference (NIH)CD3G
Genomic and cartography
GoldenPath hg38 (UCSC)CD3G  -     chr11:118344344-118353782 +  11q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CD3G  -     11q23.3   [Description]    (hg19-Feb_2009)
EnsemblCD3G - 11q23.3 [CytoView hg19]  CD3G - 11q23.3 [CytoView hg38]
Mapping of homologs : NCBICD3G [Mapview hg19]  CD3G [Mapview hg38]
OMIM186740   615607   
Gene and transcription
Genbank (Entrez)AK223314 AK299997 AK310578 AK310622 AK313966
RefSeq transcript (Entrez)NM_000073
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CD3G
Cluster EST : UnigeneHs.2259 [ NCBI ]
CGAP (NCI)Hs.2259
Alternative Splicing GalleryENSG00000160654
Gene ExpressionCD3G [ NCBI-GEO ]   CD3G [ EBI - ARRAY_EXPRESS ]   CD3G [ SEEK ]   CD3G [ MEM ]
Gene Expression Viewer (FireBrowse)CD3G [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)917
GTEX Portal (Tissue expression)CD3G
Protein : pattern, domain, 3D structure
UniProt/SwissProtP09693   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP09693  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP09693
Splice isoforms : SwissVarP09693
PhosPhoSitePlusP09693
Domaine pattern : Prosite (Expaxy)ITAM_1 (PS51055)   
Domains : Interpro (EBI)CD3_esu/gsu/dsu    Ig-like_dom    Ig-like_fold    Ig_4    Ig_sub2    Phos_immunorcpt_sig_ITAM   
Domain families : Pfam (Sanger)Ig_4 (PF16680)    ITAM (PF02189)   
Domain families : Pfam (NCBI)pfam16680    pfam02189   
Domain families : Smart (EMBL)IGc2 (SM00408)  ITAM (SM00077)  
Conserved Domain (NCBI)CD3G
DMDM Disease mutations917
Blocks (Seattle)CD3G
PDB (SRS)1SY6   
PDB (PDBSum)1SY6   
PDB (IMB)1SY6   
PDB (RSDB)1SY6   
Structural Biology KnowledgeBase1SY6   
SCOP (Structural Classification of Proteins)1SY6   
CATH (Classification of proteins structures)1SY6   
SuperfamilyP09693
Human Protein AtlasENSG00000160654
Peptide AtlasP09693
HPRD07037
IPIIPI00016020   IPI00984896   IPI00974083   
Protein Interaction databases
DIP (DOE-UCLA)P09693
IntAct (EBI)P09693
FunCoupENSG00000160654
BioGRIDCD3G
STRING (EMBL)CD3G
ZODIACCD3G
Ontologies - Pathways
QuickGOP09693
Ontology : AmiGOtransmembrane signaling receptor activity  plasma membrane  integral component of plasma membrane  protein complex assembly  establishment or maintenance of cell polarity  cell surface receptor signaling pathway  protein transport  receptor signaling complex scaffold activity  clathrin-coated vesicle membrane  T cell costimulation  Fc-gamma receptor signaling pathway involved in phagocytosis  T cell receptor complex  alpha-beta T cell receptor complex  T cell activation  T cell receptor binding  protein homodimerization activity  protein heterodimerization activity  regulation of immune response  T cell receptor signaling pathway  protein homooligomerization  membrane organization  regulation of lymphocyte apoptotic process  
Ontology : EGO-EBItransmembrane signaling receptor activity  plasma membrane  integral component of plasma membrane  protein complex assembly  establishment or maintenance of cell polarity  cell surface receptor signaling pathway  protein transport  receptor signaling complex scaffold activity  clathrin-coated vesicle membrane  T cell costimulation  Fc-gamma receptor signaling pathway involved in phagocytosis  T cell receptor complex  alpha-beta T cell receptor complex  T cell activation  T cell receptor binding  protein homodimerization activity  protein heterodimerization activity  regulation of immune response  T cell receptor signaling pathway  protein homooligomerization  membrane organization  regulation of lymphocyte apoptotic process  
Pathways : BIOCARTA [Genes]   
Pathways : KEGGHematopoietic cell lineage    T cell receptor signaling pathway    Chagas disease (American trypanosomiasis)    Measles    HTLV-I infection   
NDEx NetworkCD3G
Atlas of Cancer Signalling NetworkCD3G
Wikipedia pathwaysCD3G
Orthology - Evolution
OrthoDB917
GeneTree (enSembl)ENSG00000160654
Phylogenetic Trees/Animal Genes : TreeFamCD3G
HOVERGENP09693
HOGENOMP09693
Homologs : HomoloGeneCD3G
Homology/Alignments : Family Browser (UCSC)CD3G
Gene fusions - Rearrangements
Fusion : MitelmanFXYD6/CD3G [11q23.3/11q23.3]  [t(11;11)(q23;q23)]  
Fusion: TCGAFXYD6 11q23.3 CD3G 11q23.3 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCD3G [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CD3G
dbVarCD3G
ClinVarCD3G
1000_GenomesCD3G 
Exome Variant ServerCD3G
ExAC (Exome Aggregation Consortium)CD3G (select the gene name)
Genetic variants : HAPMAP917
Genomic Variants (DGV)CD3G [DGVbeta]
DECIPHERCD3G [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCD3G 
Mutations
ICGC Data PortalCD3G 
TCGA Data PortalCD3G 
Broad Tumor PortalCD3G
OASIS PortalCD3G [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCD3G  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCD3G
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)**PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database
BioMutasearch CD3G
DgiDB (Drug Gene Interaction Database)CD3G
DoCM (Curated mutations)CD3G (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CD3G (select a term)
intoGenCD3G
Cancer3DCD3G(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM186740    615607   
Orphanet17816   
MedgenCD3G
Genetic Testing Registry CD3G
NextProtP09693 [Medical]
TSGene917
GENETestsCD3G
Target ValidationCD3G
Huge Navigator CD3G [HugePedia]
snp3D : Map Gene to Disease917
BioCentury BCIQCD3G
ClinGenCD3G
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD917
Chemical/Pharm GKB GenePA26217
Clinical trialCD3G
Miscellaneous
canSAR (ICR)CD3G (select the gene name)
Probes
Litterature
PubMed109 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCD3G
EVEXCD3G
GoPubMedCD3G
iHOPCD3G
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:01:19 CEST 2017

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